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Regulation of auditory plasticity during critical periods and following hearing loss (2020)
Journal Article
Persic, D., Thomas, M. E., Pelekanos, V., Ryugo, D. K., Takesian, A. E., Krumbholz, K., & Pyott, S. J. (2020). Regulation of auditory plasticity during critical periods and following hearing loss. Hearing Research, 397, Article 107976. https://doi.org/10.1016/j.heares.2020.107976

Sensory input has profound effects on neuronal organization and sensory maps in the brain. The mechanisms regulating plasticity of the auditory pathway have been revealed by examining the consequences of altered auditory input during both development... Read More about Regulation of auditory plasticity during critical periods and following hearing loss.

Noise-Induced Changes of the Auditory Brainstem Response to Speech: a Measure of Neural Desynchronisation? (2020)
Journal Article
de Boer, J., Nuttall, H. E., & Krumbholz, K. (2020). Noise-Induced Changes of the Auditory Brainstem Response to Speech: a Measure of Neural Desynchronisation?. Journal of the Association for Research in Otolaryngology, 21, 183–197. https://doi.org/10.1007/s10162-020-00750-7

It is commonly assumed that difficulty in listening to speech in noise is at least partly due to deficits in neural temporal processing. Given that noise reduces the temporal fidelity of the auditory brainstem response (ABR) to speech, it has been su... Read More about Noise-Induced Changes of the Auditory Brainstem Response to Speech: a Measure of Neural Desynchronisation?.

Is human auditory cortex organization compatible with the monkey model? Contrary evidence from ultra-high-field functional and structural MRI (2018)
Journal Article
Besle, J., Mougin, O., Sánchez-Panchuelo, R.-M., Lanting, C., Gowland, P., Bowtell, R., …Krumbholz, K. (2018). Is human auditory cortex organization compatible with the monkey model? Contrary evidence from ultra-high-field functional and structural MRI. Cerebral Cortex, 29(1), 410-428. https://doi.org/10.1093/cercor/bhy267

It is commonly assumed that the human auditory cortex is organized similarly to that of macaque monkeys, where the primary region, or “core,” is elongated parallel to the tonotopic axis (main direction of tonotopic gradients), and subdivided across t... Read More about Is human auditory cortex organization compatible with the monkey model? Contrary evidence from ultra-high-field functional and structural MRI.

Auditory attention causes gain enhancement and frequency sharpening at successive stages of cortical processing: evidence from human EEG (2018)
Journal Article
de Boer, J., & Krumbholz, K. (2018). Auditory attention causes gain enhancement and frequency sharpening at successive stages of cortical processing: evidence from human EEG. Journal of Cognitive Neuroscience, 30(6), 785-798. https://doi.org/10.1162/jocn_a_01245

Previous findings have suggested that auditory attention causes not only enhancement in neural processing gain, but also sharpening in neural frequency tuning in human auditory cortex. The current study was aimed to reexamine these findings, and inve... Read More about Auditory attention causes gain enhancement and frequency sharpening at successive stages of cortical processing: evidence from human EEG.

Effect of contralateral medial olivocochlear feedback on perceptual estimates of cochlear gain and compression (2016)
Journal Article
Fletcher, M. D., Krumbholz, K., & de Boer, J. (2016). Effect of contralateral medial olivocochlear feedback on perceptual estimates of cochlear gain and compression. Journal of the Association for Research in Otolaryngology, 17(6), 559-575. https://doi.org/10.1007/s10162-016-0574-8

The active cochlear mechanism amplifies responses to low-intensity sounds, compresses the range of input sound intensities to a smaller output range, and increases cochlear frequency selectivity. The gain of the active mechanism can be modulated by t... Read More about Effect of contralateral medial olivocochlear feedback on perceptual estimates of cochlear gain and compression.

Are Interaural Time and Level Differences Represented by Independent or Integrated Codes in the Human Auditory Cortex? (2013)
Journal Article
Edmonds, B. A., & Krumbholz, K. (2014). Are Interaural Time and Level Differences Represented by Independent or Integrated Codes in the Human Auditory Cortex?. Journal of the Association for Research in Otolaryngology, 15(1), 103-114. https://doi.org/10.1007/s10162-013-0421-0

Sound localization is important for orienting and focusing attention and for segregating sounds from different sources in the environment. In humans, horizontal sound localization mainly relies on interaural differences in sound arrival time and soun... Read More about Are Interaural Time and Level Differences Represented by Independent or Integrated Codes in the Human Auditory Cortex?.

Is Overshoot Caused by an Efferent Reduction in Cochlear Gain?
Presentation / Conference Contribution
Fletcher, M., de Boer, J., & Krumbholz, K. (2012, July). Is Overshoot Caused by an Efferent Reduction in Cochlear Gain?. Presented at International Symposium on Hearing, Cambridge, UK

Under certain conditions, detection of a masked tone is improved by a preceding sound ("precursor"). This phenomenon is referred to as the "temporal effect" or "overshoot". A prevalent model of overshoot, referred to as the "gain reduction model", po... Read More about Is Overshoot Caused by an Efferent Reduction in Cochlear Gain?.