All Outputs (9)

Investor clientele and intraday patterns in the cross section of stock returns (2024)
Journal Article
Chen, J., Haboub, A., Khan, A., & Mahmud, S. (2024). Investor clientele and intraday patterns in the cross section of stock returns. Review of Quantitative Finance and Accounting, https://doi.org/10.1007/s11156-024-01319-8

This paper examines the existence of a well documented (Heston et al. in J Finance 65:1369–1407) (hereafter HKS 2010) intraday momentum pattern in the cross section of stock returns for three previously un-examined markets outside the US—UK, China an... Read More about Investor clientele and intraday patterns in the cross section of stock returns.

Limits of arbitrage and their impact on market efficiency: Evidence from China (2023)
Journal Article
Chen, J., Haboub, A., & Khan, A. (2024). Limits of arbitrage and their impact on market efficiency: Evidence from China. Global Finance Journal, 59, Article 100916. https://doi.org/10.1016/j.gfj.2023.100916

This paper examines the impact of limits of arbitrage (LOA) on market efficiency by considering a large sample of Chinese stocks. Intraday market efficiency is measured using two widely used measures: the intraday return predictability measure and th... Read More about Limits of arbitrage and their impact on market efficiency: Evidence from China.

Synthesis and bioevaluation of novel stilbene-based derivatives as tubulin/HDAC dual-target inhibitors with potent antitumor activities in vitro and in vivo (2023)
Journal Article
Zhu, H., Zhu, W., Liu, Y., Gao, T., Zhu, J., Tan, Y., Hu, H., Liang, W., Zhao, L., Chen, J., Zhu, Z., Chen, J., Xu, J., & Xu, S. (2023). Synthesis and bioevaluation of novel stilbene-based derivatives as tubulin/HDAC dual-target inhibitors with potent antitumor activities in vitro and in vivo. European Journal of Medicinal Chemistry, 257, Article 115529. https://doi.org/10.1016/j.ejmech.2023.115529

A series of novel stilbene-based derivatives were designed and synthesized as tubulin/HDAC dual-target inhibitors. Among forty-three target compounds, compound II-19k not only exhibited considerable antiproliferative activity in the hematological cel... Read More about Synthesis and bioevaluation of novel stilbene-based derivatives as tubulin/HDAC dual-target inhibitors with potent antitumor activities in vitro and in vivo.

Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation (2023)
Journal Article
Xue, S., Li, Z., Ze, X., Wu, X., He, C., Shuai, W., Marlow, M., Chen, J., Scurr, D., Zhu, Z., Xu, J., & Xu, S. (2023). Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation. Journal of Medicinal Chemistry, 66(7), 5099–5117. https://doi.org/10.1021/acs.jmedchem.3c00012

Excessive melanin deposition may lead to a series of skin disorders. The production of melanin is carried out by melanocytes, in which the enzyme tyrosinase performs a key role. In this work, we identified a series of novel tyrosinase inhibitor hybri... Read More about Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation.

Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation (2023)
Journal Article
Xie, S., Zhan, F., Zhu, J., Sun, Y., Zhu, H., Liu, J., Chen, J., Zhu, Z., Yang, D.-H., Chen, Z.-S., Yao, H., Xu, J., & Xu, S. (2023). Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation. Angewandte Chemie International Edition, 62(13), Article e202217246. https://doi.org/10.1002/anie.202217246

Hydrophobic tagging (HyT) is a potential therapeutic strategy for targeted protein degradation (TPD). Norbornene was discovered as an unprecedented hydrophobic tag in this study and was used to degrade the anaplastic lymphoma kinase (ALK) fusion prot... Read More about Discovery of Norbornene as a Novel Hydrophobic Tag Applied in Protein Degradation.

Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset? (2021)
Journal Article
Schilling, K. G., Rheault, F., Petit, L., Hansen, C. B., Nath, V., Yeh, F. C., Girard, G., Barakovic, M., Rafael-Patino, J., Yu, T., Fischi-Gomez, E., Pizzolato, M., Ocampo-Pineda, M., Schiavi, S., Canales-Rodríguez, E. J., Daducci, A., Granziera, C., Innocenti, G., Thiran, J. P., Mancini, L., …Descoteaux, M. (2021). Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?. NeuroImage, 243, Article 118502. https://doi.org/10.1016/j.neuroimage.2021.118502

White matter bundle segmentation using diffusion MRI fiber tractography has become the method of choice to identify white matter fiber pathways in vivo in human brains. However, like other analyses of complex data, there is considerable variability i... Read More about Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?.

Foreign investment, corporate governance and performance in the Chinese listed A Share companies (2017)
Journal Article
Beatson, S. A., & Chen, J. (2018). Foreign investment, corporate governance and performance in the Chinese listed A Share companies. Journal of Chinese Economic and Business Studies, 16(1), 59-93. https://doi.org/10.1080/14765284.2017.1346931

We present a novel lens on the presence and impact of qualified foreign institutional investors (QFII) in top shareholdings of the non-financial domestically listed Chinese ‘A’ share firms. The initial results suggest that the presence of a QFII as a... Read More about Foreign investment, corporate governance and performance in the Chinese listed A Share companies.

Introduction to China’s new normal economy (2017)
Journal Article
Zhang, J., & Chen, J. (in press). Introduction to China’s new normal economy. Journal of Chinese Economic and Business Studies, 15(1), https://doi.org/10.1080/14765284.2017.1289454

China’s economic reform has been successful, making it become a major economic power. Largely relied on low-cost investment, cheap and abundant labour and use of natural resources to support growth, China has faced a number of challenges including hi... Read More about Introduction to China’s new normal economy.

What determine firms’ capital structure in China? (2014)
Journal Article
Chen, J., Jiang, C., & Lin, Y. (2014). What determine firms’ capital structure in China?. Managerial Finance, 40(10), https://doi.org/10.1108/MF-06-2013-0163

Purpose: The purpose of this paper is to investigate the determinants of capital structure using a cross-section sample of 1,481 non-financial firms listed on the Chinese stock exchanges in 2011.
Design/methodology/approach: Employing four leverage... Read More about What determine firms’ capital structure in China?.