A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data

Bishton, Mark; Stilwell, Peter; Card, Tim R; Lanyon, Peter; Ban, Lu; Elliss-Brookes, Lucy; Manson, Jessica; Nanduri, Vasanta; Earp, Kate; Flower, Luke; Amarnani, Raj; Rankin, Judith; Sen, Ethan S; Tattersall, Rachel S; Crooks, Colin J; Aston, Jeanette; Siskova, Veronika; West, Joe; Bythell, Mary

All Outputs (2)

Temporal trends in the incidence of haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003-2018 (2022)
Working Paper
West, J., Stilwell, P., Liu, H., Ban, L., Bythell, M., Card, T. R., …Crooks, C. J. Temporal trends in the incidence of haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003-2018

Background Haemophagocytic lymphohistiocytosis (HLH) is rare, results in high mortality and is increasingly being diagnosed. Little is known about what is driving the apparent rise in the incidence of this disease. Methods Using national linked el... Read More about Temporal trends in the incidence of haemophagocytic lymphohistiocytosis: a nationwide cohort study from England 2003-2018.

A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data (2021)
Working Paper
Bishton, M., Stilwell, P., Card, T. R., Lanyon, P., Ban, L., Elliss-Brookes, L., …Bythell, M. A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data

We assessed the validity of coded health care data to identify cases of haemophagocytic lymphohistiocytosis (HLH). Hospital Episode Statistics (HES) identified 127 cases within five hospital Trusts 2013-2018 using ICD-10 codes D76.1, D76.2 and D76.3.... Read More about A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data.