All Outputs (3)

Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices (2021)
Journal Article
He, Y., Abdi, M., Trindade, G. F., Begines, B., Dubern, J. F., Prina, E., Hook, A. L., Choong, G. Y., Ledesma, J., Tuck, C. J., Rose, F. R., Hague, R. J., Roberts, C. J., De Focatiis, D. S., Ashcroft, I. A., Williams, P., Irvine, D. J., Alexander, M. R., & Wildman, R. D. (2021). Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices. Advanced Science, 8(15), Article 2100249. https://doi.org/10.1002/advs.202100249

As the understanding of disease grows, so does the opportunity for personalization of therapies targeted to the needs of the individual. To bring about a step change in the personalization of medical devices it is shown that multi-material inkjet-bas... Read More about Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices.

The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells (2020)
Journal Article
Ruiter, F. A., Sidney, L. E., Kiick, K. L., Segal, J. I., Alexander, C., & Rose, F. R. A. J. (2020). The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells. Biomaterials Science, 8(9), 2611-2626. https://doi.org/10.1039/c9bm01965k

Current cell expansion methods for tissue engineering and regenerative medicine applications rely on the use of enzymatic digestion passaging and 2D platforms. However, this enzymatic treatment significantly reduces cell quality, due to the destructi... Read More about The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells.

A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants (2020)
Journal Article
He, Y., Foralosso, R., Ferraz Trindade, G., Ilchev, A., Cantu, L. R., Clark, E., Khaled, S., Hague, R. J. M., Tuck, C. J., Rose, F. R. A. J., Mantovani, G., Irvine, D., Roberts, C. J., & Wildman, R. D. (2020). A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants. Advanced Therapeutics, 3(6), Article 1900187. https://doi.org/10.1002/adtp.201900187

We propose a strategy for creating tuneable 3D printed drug delivery devices. 3D printing offers the opportunity for improved compliance and patient treatment outcomes through personalisation, but bottlenecks include finding formulations that provide... Read More about A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants.