Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs
(2015)
Journal Article
Dhir, A., Dhir, S., Proudfoot, N. J., & Jopling, C. L. (2015). Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. Nature Structural and Molecular Biology, 22, https://doi.org/10.1038/nsmb.2982
MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. Mammalian miRNA biogenesis begins with co-transcriptional cleavage of RNA polymerase II (Pol II) transcripts by the Microprocessor complex. While most miRNA... Read More about Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs.