A model for the compressible, viscoelastic behavior of human amnion addressing tissue variability through a single parameter

Mauri, Arabella; Ehret, Alexander E.; De Focatiis, Davide S.A.; Mazza, Edoardo

Abstract

A viscoelastic, compressible model is proposed to rationalize the recently reported response of human amnion in multiaxial relaxation and creep experiments. The theory includes two viscoelastic contributions responsible for the short- and long-term time- dependent response of the material. These two contributions can be related to physical processes: water flow through the tissue and dissipative characteristics of the collagen fibers, respectively. An accurate agreement of the model with the mean tension and kinematic response of amnion in uniaxial relaxation tests was achieved. By variation of a single linear factor that accounts for the variability among tissue samples, the model provides very sound predictions not only of the uniaxial relaxation but also of the uniaxial creep and strip-biaxial relaxation behavior of individual samples. This suggests that a wide range of viscoelastic behaviors due to patient-specific variations in tissue composition.

Citation

Mauri, A., Ehret, A. E., De Focatiis, D. S., & Mazza, E. (2016). A model for the compressible, viscoelastic behavior of human amnion addressing tissue variability through a single parameter. Biomechanics and Modeling in Mechanobiology, 15(4), 1005-1017. https://doi.org/10.1007/s10237-015-0739-0

• Journal Article Type: Article
• Acceptance Date: Oct 9, 2015
• Online Publication Date: Oct 23, 2015
• Publication Date: Aug 31, 2016
• Deposit Date: Sep 5, 2017
• Publicly Available Date: Sep 5, 2017
• Journal: Biomechanics and Modeling in Mechanobiology
• Print ISSN: 1617-7959
• Electronic ISSN: 1617-7940
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 15
• Issue: 4
• Pages: 1005-1017
• DOI: https://doi.org/10.1007/s10237-015-0739-0
• Keywords: Biological Membrane, Compressible Viscoelastic Model, � Specimen Variability, Human Amnion,� Creep, Stress Relaxation
• Public URL: https://nottingham-repository.worktribe.com/output/803723
• Publisher URL: https://link.springer.com/article/10.1007%2Fs10237-015-0739-0
• Additional Information: The final publication is available at Springer via http://dx.doi.org/10.1007/s10237-015-0739-0.
• Contract Date: Sep 5, 2017