Interspecific introgression mediates adaptation to whole genome duplication

Marburger, Sarah; Monnahan, Patrick; Seear, Paul J.; Martin, Simon H.; Koch, Jordan; Paajanen, Pirita; Bohut�nsk�, Magdalena; Higgins, James D.; Schmickl, Roswitha; Yant, Levi

Abstract

Adaptive gene flow is a consequential phenomenon across all kingdoms. While recognition is increasing, examples lack of bidirectional gene flow mediating adaptations at loci that manage core processes. We previously discovered concerted molecular changes among interacting members of meiotic machinery controlling crossover number upon adaptation to whole genome duplication (WGD) in Arabidopsis arenosa. Here we conduct a population genomic study to test the hypothesis that adaptation to WGD has been mediated by adaptive gene flow between A. arenosa and A. lyrata. We find that A. lyrata underwent WGD more recently than A. arenosa, suggesting that pre-adapted alleles have rescued nascent A. lyrata, but we also detect gene flow in the opposite direction at functionally interacting loci under the most extreme levels of selection. These data indicate that bidirectional gene flow allowed for survival after WGD and that the merger of these species is greater than the sum of their parts.

Citation

Marburger, S., Monnahan, P., Seear, P. J., Martin, S. H., Koch, J., Paajanen, P., Bohutínská, M., Higgins, J. D., Schmickl, R., & Yant, L. (2019). Interspecific introgression mediates adaptation to whole genome duplication. Nature Communications, 10, Article 5218. https://doi.org/10.1038/s41467-019-13159-5

• Journal Article Type: Article
• Acceptance Date: Oct 24, 2019
• Online Publication Date: Nov 18, 2019
• Publication Date: Nov 18, 2019
• Deposit Date: Oct 31, 2019
• Publicly Available Date: Nov 18, 2019
• Journal: Nature Communications
• Electronic ISSN: 2041-1723
• Publisher: Nature Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 10
• Article Number: 5218
• DOI: https://doi.org/10.1038/s41467-019-13159-5
• Keywords: General Biochemistry, Genetics and Molecular Biology; General Physics and Astronomy; General Chemistry
• Public URL: https://nottingham-repository.worktribe.com/output/2999532
• Publisher URL: https://www.nature.com/articles/s41467-019-13159-5
• Additional Information: Received: 1 May 2019; Accepted: 24 October 2019; First Online: 18 November 2019; : The authors declare no competing interests.
• Contract Date: Oct 31, 2019