Outputs (193)

Mortality rates among patients successfully treated for hepatitis C in the era of interferon-free antivirals: population based cohort study (2023)
Journal Article
Hamill, V., Wong, S., Benselin, J., Krajden, M., Hayes, P. C., Mutimer, D., Yu, A., Dillon, J. F., Gelson, W., Velásquez García, H. A., Yeung, A., Johnson, P., Barclay, S. T., Alvarez, M., Toyoda, H., Agarwal, K., Fraser, A., Bartlett, S., Aldersley, M., Bathgate, A., …Innes, H. (2023). Mortality rates among patients successfully treated for hepatitis C in the era of interferon-free antivirals: population based cohort study. BMJ, 382, Article e074001. https://doi.org/10.1136/bmj-2022-074001

Objectives To quantify mortality rates for patients successfully treated for hepatitis C in the era of interferon-free, direct acting antivirals and compare these rates with those of the general population.

Design Population based cohort study.... Read More about Mortality rates among patients successfully treated for hepatitis C in the era of interferon-free antivirals: population based cohort study.

Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY (2023)
Journal Article
Pearce, F. A., Lim, S. H., Bythell, M., Lanyon, P., Hogg, R., Taylor, A., Powter, G., Cooke, G. S., Ward, H., Chilcot, J., Thomas, H., Mumford, L., McAdoo, S. P., Pettigrew, G. J., Lightstone, L., & Willicombe, M. (2023). Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY. The Lancet Rheumatology, 5(8), E461-E473. https://doi.org/10.1016/S2665-9913%2823%2900160-1

Background:
In the UK, additional COVID-19 vaccine booster doses and treatments are offered to people who are immunosuppressed to protect against severe COVID-19, but how best to choose the individuals that receive these vaccine booster doses and t... Read More about Antibody prevalence after three or more COVID-19 vaccine doses in individuals who are immunosuppressed in the UK: a cross-sectional study from MELODY.

Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy (2023)
Journal Article
Przulj, D., Pesola, F., Myers Smith, K., McRobbie, H., Coleman, T., Lewis, S., Griffith, C., Walton, R., Whitemore, R., Clark, M., Ussher, M., Sinclair, L., Seager, E., Cooper, S., Bauld, L., Naughton, F., Sasieni, P., Manyonda, I., & Hajek, P. (2023). Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy. Health Technology Assessment, 27(13), https://doi.org/10.3310/AGTH6901

Background
Some pregnant smokers try e-cigarettes, but effectiveness and safety of such use are unknown.

Objectives
To compare effectiveness and safety of nicotine patches and e-cigarettes in pregnancy.

Design
A pragmatic multi-centre random... Read More about Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy.

Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’ (2023)
Journal Article
Shanmugavadivel, D., Liu, J.-F., Ball-Gamble, A., Polanco, A., Vedhara, K., Nathan, P., Walker, D., & Ojha, S. (2023). Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’. British Journal of General Practice, 73(733), 377-379. https://doi.org/10.3399/bjgp23x734673

In 2018, the World Health Organization declared childhood cancer as a global disease burden, launching a Global Initiative to improve survival to 60% worldwide by 2030. If achieved, it is estimated that an extra 1 million children’s lives will be sav... Read More about Childhood bone tumours in primary care: helping GPs to identify ‘the needle in the haystack’.

Managing raised ferritin in primary care (2023)
Journal Article
Stewart, S., Evans, W., Turnbull, I., Bradbury, C., Hayward, J., & Shearman, J. (2023). Managing raised ferritin in primary care. BMJ, 382, Article e076750. https://doi.org/10.1136/bmj-2023-076750

Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England (2023)
Journal Article
Alothman, D., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. W. (2023). Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England. The Lancet Regional Health Europe, 32, Article 100695. https://doi.org/10.1016/j.lanepe.2023.100695

Background: Analgesics prescriptions may provide a marker for identifying individuals at higher risk of suicide. In particular, awareness of which analgesics are implicated may help clinicians assess and modify risk. Method: A case–control study in E... Read More about Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England.

Multinational prescribing trends of lithium from 2001 to 2019: a retrospective observational study using population-based databases from 17 countries and one special administrative region (2023)
Journal Article
Chan, A. Y., Chan, V. K., Bahmanyar, S., Beyene, K., Bushnell, G., Carleton, B., Chan, A., Cook, S., Crystal, S., Furu, K., Gadzhanova, S., Poza, P. G., Giometto, S., Gini, R., Harrison, J., Haug, U., Hayes, J. F., Hsu, C., Jónsdóttir, H. L., Kai, J., …Wong, I. C. K. Multinational prescribing trends of lithium from 2001 to 2019: a retrospective observational study using population-based databases from 17 countries and one special administrative region. Manuscript submitted for publication

Social determinants of health and vaccine uptake during the first wave of the COVID-19 pandemic: A systematic review (2023)
Journal Article
Vardavas, C., Nikitara, K., Aslanoglou, K., Lagou, I., Marou, V., Phalkey, R., Leonardi-Bee, J., Fernandez, E., Vivilaki, V., Kamekis, A., Symvoulakis, E., Noori, T., Wuerz, A., Suk, J. E., & Deogan, C. (2023). Social determinants of health and vaccine uptake during the first wave of the COVID-19 pandemic: A systematic review. Preventive Medicine Reports, 35, Article 102319. https://doi.org/10.1016/j.pmedr.2023.102319

Social determinants of health significantly impact population health status. The aim of this systematic review was to examine which social vulnerability factors or determinants of health at the individual or county level affected vaccine uptake withi... Read More about Social determinants of health and vaccine uptake during the first wave of the COVID-19 pandemic: A systematic review.

Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) (2023)
Journal Article
Ogliari, G., Ryg, J., Andersen-Ranberg, K., Scheel-Hincke, L. L., Collins, J. T., Cowley, A., Di Lorito, C., Booth, V., Smit, R. A. J., Akyea, R. K., Qureshi, N., Walsh, D. A., Harwood, R. H., & Masud, T. (2023). Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE). European Geriatric Medicine, 14(5), 1111-1124. https://doi.org/10.1007/s41999-023-00835-5

Purpose
To investigate the longitudinal associations between pain and depressive symptoms in adults.

Methods
Prospective cohort study on data from 28,515 community-dwelling adults ≥ 50 years, free from depression at baseline (Wave 5), with follo... Read More about Association between pain intensity and depressive symptoms in community-dwelling adults: longitudinal findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).

How frequent is routine use of probiotics in UK neonatal units? (2023)
Journal Article
Patel, N., Evans, K., Berrington, J., Szatkowski, L., Costeloe, K., Ojha, S., Fleming, P., Battersby, C., & NeoTRIPS Collaborative Group. (2023). How frequent is routine use of probiotics in UK neonatal units?. BMJ Paediatrics Open, 7(1), Article e002012. https://doi.org/10.1136/bmjpo-2023-002012

Objective There is a lack of UK guidance regarding routine use of probiotics in preterm infants to prevent necrotising enterocolitis, late-onset sepsis and death. As practices can vary, we aimed to determine the current usage of probiotics within neo... Read More about How frequent is routine use of probiotics in UK neonatal units?.