Outputs (193)

Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data (2023)
Journal Article
Jack, R. H., Joseph, R. M., Hollis, C., Hippisley-Cox, J., Butler, D., Waldram, D., & Coupland, C. (2023). Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data. BMJ Mental Health, 26(1), Article e300855. https://doi.org/10.1136/bmjment-2023-300855

Background There is an increasing demand for mental health services for young people, which may vary across the year.

Objective To determine whether there are seasonal patterns in primary care antidepressant prescribing and mental health issues in... Read More about Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data.

Cost of the COVID-19 pandemic versus the cost-effectiveness of mitigation strategies in EU/UK/OECD: a systematic review (2023)
Journal Article
Vardavas, C., Zisis, K., Nikitara, K., Lagou, I., Marou, V., Aslanoglou, K., Athanasakis, K., Phalkey, R., Leonardi-Bee, J., Fernandez, E., Condell, O., Lamb, F., Sandmann, F., Pharris, A., Deogan, C., & Suk, J. E. (2023). Cost of the COVID-19 pandemic versus the cost-effectiveness of mitigation strategies in EU/UK/OECD: a systematic review. BMJ Open, 13(10), Article e077602. https://doi.org/10.1136/bmjopen-2023-077602

OBJECTIVES: The economic burden of COVID-19 pandemic is substantial, with both direct and indirect costs playing a significant role. DESIGN: A systematic literature review was conducted to estimate the cost of the COVID-19 pandemic and the cost-effec... Read More about Cost of the COVID-19 pandemic versus the cost-effectiveness of mitigation strategies in EU/UK/OECD: a systematic review.

Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study (2023)
Journal Article
Holden, M. A., Hawarden, A., Paskins, Z., Roddy, E., Mallen, C. D., Liddle, J., Bourton, A., & Jinks, C. (2023). Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study. Musculoskeletal Care, 21(4), 1601-1611. https://doi.org/10.1002/msc.1830

Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic or local anaesthetic alone to advice and education among people with hi... Read More about Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study.

Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study (2023)
Journal Article
Szatkowski, L., Sharkey, D., Budge, H., & Ojha, S. (2023). Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study. eClinicalMedicine, 65, Article 102296. https://doi.org/10.1016/j.eclinm.2023.102296

Background: Preterm infants often require mechanical ventilation (MV), which can be a painful experience. Opioids (such as morphine) are used to provide analgesia, despite conflicting evidence about their impact on the developing brain. We aimed to q... Read More about Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study.

Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary Care (2023)
Journal Article
Bailey, J. A., Morton, A. J., Jones, J., Chapman, C. J., Oliver, S., Morling, J. R., Patel, H., Banerjea, A., & Humes, D. J. (2023). Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary Care. British Journal of General Practice, 73(736), e843-e849. https://doi.org/10.3399/bjgp.2023.0033

Background: Faecal Immunochemical Testing (FIT) usage for symptomatic patients is increasing, but variations in use by sociodemographics are unknown. We introduced FIT for symptomatic patients in November 2017. Aim: Identify whether demographics, eth... Read More about Sociodemographic Variations in the Uptake of Faecal Immunochemical Tests in Primary Care.

Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study (2023)
Journal Article
Thompson, W., Swain, S., Zhao, S. S., Kamps, A., Coupland, C., Kuo, C., Bierma-Zeinstra, S., Runhaar, J., Doherty, M., & Zhang, W. (2023). Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study. Osteoarthritis and Cartilage Open, 5(4), Article 100414. https://doi.org/10.1016/j.ocarto.2023.100414

Objective To investigate the causal association between Osteoarthritis (OA) and five comorbidities: depression, tiredness, multisite chronic pain, irritable bowel syndrome (IBS) and gout.... Read More about Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study.

Community-based rehabilitation intervention for people with schizophrenia in Ethiopia (RISE) cluster-randomised controlled trial: An exploratory analysis of impact on food insecurity, underweight, alcohol use disorder and depressive symptoms (2023)
Journal Article
Asher, L., Birhane, R., Weiss, H., Medhin, G., Selamu, M., Patel, V., de Silva, M., Hanlon, C., & Fekadu, A. (2023). Community-based rehabilitation intervention for people with schizophrenia in Ethiopia (RISE) cluster-randomised controlled trial: An exploratory analysis of impact on food insecurity, underweight, alcohol use disorder and depressive symptoms. Cambridge Prisms: Global Mental Health, 10, Article E70. https://doi.org/10.1017/gmh.2023.67

We evaluated the effectiveness of community-based rehabilitation (CBR) in reducing depressive symptoms, alcohol use disorder, food insecurity and underweight in people with schizophrenia. This cluster-randomised controlled trial was conducted in a ru... Read More about Community-based rehabilitation intervention for people with schizophrenia in Ethiopia (RISE) cluster-randomised controlled trial: An exploratory analysis of impact on food insecurity, underweight, alcohol use disorder and depressive symptoms.

Migrants’ living conditions, perceived health needs and implications for the use of antibiotics and antimicrobial resistance in the United Kingdom: a qualitative study (2023)
Journal Article
Nanakali, S. S., Hassan, O., Silva, L., Al-Oraibi, A., Chaloner, J., Gogoi, M., Qureshi, I., Sahare, P., Pareek, M., Chattopadhyay, K., & Nellums, L. B. (2023). Migrants’ living conditions, perceived health needs and implications for the use of antibiotics and antimicrobial resistance in the United Kingdom: a qualitative study. Health Science Reports, 6(10), Article e1655. https://doi.org/10.1002/hsr2.1655

Background and Aims:
Antimicrobial resistance (AMR) is among the top public health concerns around the globe. Migrants, especially forced migrants, could be at higher risk of acquiring and transmitting AMR during their journeys or in host countries.... Read More about Migrants’ living conditions, perceived health needs and implications for the use of antibiotics and antimicrobial resistance in the United Kingdom: a qualitative study.

Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis (2023)
Journal Article
Qureshi, N., Woods, B., Neves de Faria, R., Saramago Goncalves, P., Cox, E., Leonardi Bee, J., Condon, L., Weng, S., Akyea, R. K., Iyen, B., Roderick, P., Humphries, S. E., Rowlands, W., Watson, M., Haralambos, K., Kenny, R., Datta, D., Miedzybrodzka, Z., Byrne, C., & Kai, J. (2023). Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis. Health Technology Assessment, 27(16), 1-140. https://doi.org/10.3310/CTMD0148

Background
Cascade testing the relatives of people with familial hypercholesterolaemia is an efficient approach to identifying familial hypercholesterolaemia. The cascade-testing protocol starts with identifying an index patient with familial hyperc... Read More about Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis.

Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT (2023)
Journal Article
Ridd, M. J., Wells, S., MacNeill, S. J., Sanderson, E., Webb, D., Banks, J., Sutton, E., Shaw, A. R., Wilkins, Z., Clayton, J., Roberts, A., Garfield, K., Liddiard, L., Barrett, T. J., Lane, J. A., Baxter, H., Howells, L., Taylor, J., Hay, A. D., Williams, H. C., …Santer, M. (2023). Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT. Health Technology Assessment, 27(19), 1-120. https://doi.org/10.3310/gzqw6681

Background: Emollients are recommended for children with eczema (atopic eczema/dermatitis). A lack of head-to-head comparisons of the effectiveness and acceptability of the different types of emollients has resulted in a 'trial and error' approach to... Read More about Comparison of lotions, creams, gels and ointments for the treatment of childhood eczema: the BEE RCT.