Outputs (2)

Kisspeptin-54 Accurately Identifies Hypothalamic Gonadotropin-Releasing Hormone Neuronal Dysfunction in Men with Congenital Hypogonadotropic Hypogonadism (2020)
Journal Article
Abbara, A., Eng, P. C., Phylactou, M., Clarke, S. A., Mills, E., Chia, G., Yang, L., Izzi-Engbeaya, C., Smith, N., Jayasena, C. N., Comninos, A. N., Anand-Ivell, R., Rademaker, J., Xu, C., Quinton, R., Pitteloud, N., & Dhillo, W. S. (2021). Kisspeptin-54 Accurately Identifies Hypothalamic Gonadotropin-Releasing Hormone Neuronal Dysfunction in Men with Congenital Hypogonadotropic Hypogonadism. Neuroendocrinology, 111(12), 1176-1186. https://doi.org/10.1159/000513248

Background: Hypogonadotropic hypogonadism (HH) is hypogonadism due to either hypothalamic or pituitary dysfunction. While gonadotropin-releasing hormone (GnRH) can directly test pituitary function, no specific test of hypothalamic function exists. Ki... Read More about Kisspeptin-54 Accurately Identifies Hypothalamic Gonadotropin-Releasing Hormone Neuronal Dysfunction in Men with Congenital Hypogonadotropic Hypogonadism.

Physiology and evolution of the INSL3/RXFP2 hormone/receptor system in higher vertebrates (2020)
Journal Article
Ivell, R., Alhujaili, W., Kohsaka, T., & Anand-Ivell, R. (2020). Physiology and evolution of the INSL3/RXFP2 hormone/receptor system in higher vertebrates. General and Comparative Endocrinology, 299, Article 113583. https://doi.org/10.1016/j.ygcen.2020.113583

© 2020 Elsevier Inc. Although the insulin-like peptide hormone INSL3 and its cognate receptor RXFP2 (relaxin-family peptide receptor 2) have existed throughout chordate evolution, their physiological diversification appears to be linked closely with... Read More about Physiology and evolution of the INSL3/RXFP2 hormone/receptor system in higher vertebrates.