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The phosphoenolpyruvate carboxykinase (PEPCK) inhibitor, 3-mercaptopicolinic acid (3-MPA), induces myogenic differentiation in C2C12 cells (2020)
Journal Article
Brearley, M. C., Daniel, Z. C., Loughna, P. T., Parr, T., & Brameld, J. M. (2020). The phosphoenolpyruvate carboxykinase (PEPCK) inhibitor, 3-mercaptopicolinic acid (3-MPA), induces myogenic differentiation in C2C12 cells. Scientific Reports, 10, Article 22177. https://doi.org/10.1038/s41598-020-79324-9

Phosphoenolpyruvate carboxykinase (PEPCK) is a gluconeogenic enzyme with a cytosolic (Pck1/PEPCK-C) and mitochondrial (Pck2/PEPCK-M) isoform. Here we investigate the effect of 3-mercaptopicolinic acid (3-MPA), a PEPCK inhibitor, on C2C12 muscle cells... Read More about The phosphoenolpyruvate carboxykinase (PEPCK) inhibitor, 3-mercaptopicolinic acid (3-MPA), induces myogenic differentiation in C2C12 cells.

A stable isotope approach to accurately determine iron and zinc bioaccessibility in cereals and legumes based on a modified INFOGEST static in vitro digestion method (2020)
Journal Article
Muleya, M., Young, S. D., & Bailey, E. H. (2021). A stable isotope approach to accurately determine iron and zinc bioaccessibility in cereals and legumes based on a modified INFOGEST static in vitro digestion method. Food Research International, 139, Article 109948. https://doi.org/10.1016/j.foodres.2020.109948

© 2020 Elsevier Ltd The establishment of the INFOGEST in vitro static digestion method, a standardized international consensus, was an important milestone in the field of food digestion. We evaluated the contribution of iron and zinc in reagents used... Read More about A stable isotope approach to accurately determine iron and zinc bioaccessibility in cereals and legumes based on a modified INFOGEST static in vitro digestion method.

Analysis of bovine blastocysts indicates ovarian stimulation does not induce chromosome errors, nor discordance between inner-cell mass and trophectoderm lineages (2020)
Journal Article
Tutt, D. A., Silvestri, G., Serrano-Albal, M., Simmons, R. J., Kwong, W. Y., Guven-Ates, G., Canedo-Ribeiro, C., Labrecque, R., Blondin, P., Handyside, A. H., Griffin, D. .., & Sinclair, K. D. (2021). Analysis of bovine blastocysts indicates ovarian stimulation does not induce chromosome errors, nor discordance between inner-cell mass and trophectoderm lineages. Theriogenology, 161, 108-119. https://doi.org/10.1016/j.theriogenology.2020.11.021

© 2020 The Authors Contemporary systems for oocyte retrieval and culture of both cattle and human embryos are suboptimal with respect to pregnancy outcomes following transfer. In humans, chromosome abnormalities are the leading cause of early pregnan... Read More about Analysis of bovine blastocysts indicates ovarian stimulation does not induce chromosome errors, nor discordance between inner-cell mass and trophectoderm lineages.

Arabidopsis antibody resources for functional studies in plants (2020)
Journal Article
Oh, J., Wilson, M., Hill, K., Leftley, N., Hodgman, C., Bennett, M. J., & Swarup, R. (2020). Arabidopsis antibody resources for functional studies in plants. Scientific Reports, 10(1), Article 21945. https://doi.org/10.1038/s41598-020-78689-1

© 2020, The Author(s). Here we report creation of a unique and a very valuable resource for Plant Scientific community worldwide. In this era of post-genomics and modelling of multi-cellular systems using an integrative systems biology approach, bett... Read More about Arabidopsis antibody resources for functional studies in plants.

Understanding the lost functionality of ethanol in non-alcoholic beer using sensory evaluation, aroma release and molecular hydrodynamics (2020)
Journal Article
Ramsey, I., Dinu, V., Linforth, R., Yakubov, G. E., Harding, S. E., Yang, Q., Ford, R., & Fisk, I. (2020). Understanding the lost functionality of ethanol in non-alcoholic beer using sensory evaluation, aroma release and molecular hydrodynamics. Scientific Reports, 10(1), Article 20855. https://doi.org/10.1038/s41598-020-77697-5

© 2020, The Author(s). Consumer sensory evaluation, aroma release analysis and biophysical protein analysis were used to investigate the effect of ethanol on the release and perception of flavour in beer (lager and stout) at different ethanol levels... Read More about Understanding the lost functionality of ethanol in non-alcoholic beer using sensory evaluation, aroma release and molecular hydrodynamics.

Thermal taster status: Temperature modulation of cortical response to sweetness perception (2020)
Journal Article
Eldeghaidy, S., Yang, Q., Abualait, T., Williamson, A.-M., Hort, J., & Francis, S. T. (2021). Thermal taster status: Temperature modulation of cortical response to sweetness perception. Physiology and Behavior, 230, Article 113266. https://doi.org/10.1016/j.physbeh.2020.113266

© 2020 Temperature is known to impact taste perception, but its reported effect on sweet taste perception in humans is inconsistent. Here, we assess whether thermal taste phenotype alters the temperature modulation of the brains’ response to sweet sa... Read More about Thermal taster status: Temperature modulation of cortical response to sweetness perception.

Genome-wide association mapping for grain manganese in rice (Oryza sativa L.) using a multi-experiment approach (2020)
Journal Article
Ruang-areerate, P., Travis, A. J., Pinson, S. R. M., Tarpley, L., Eizenga, G. C., Guerinot, M. L., Salt, D. E., Douglas, A., Price, A. H., & Norton, G. J. (2021). Genome-wide association mapping for grain manganese in rice (Oryza sativa L.) using a multi-experiment approach. Heredity, 126(3), 505-520. https://doi.org/10.1038/s41437-020-00390-w

Manganese (Mn) is an essential trace element for plants and commonly contributes to human health; however, the understanding of the genes controlling natural variation in Mn in crop plants is limited. Here, the integration of two of genome-wide assoc... Read More about Genome-wide association mapping for grain manganese in rice (Oryza sativa L.) using a multi-experiment approach.

Coordination between microbiota and root endodermis supports plant mineral nutrient homeostasis (2020)
Journal Article
Salas-González, I., Reyt, G., Flis, P., Custódio, V., Gopaulchan, D., Bakhoum, N., Dew, T. P., Suresh, K., Franke, R. B., Dangl, J. L., Salt, D. E., & Castrillo, G. (2021). Coordination between microbiota and root endodermis supports plant mineral nutrient homeostasis. Science, 371(6525), Article eabd0695. https://doi.org/10.1126/science.abd0695

Copyright © 2021, American Association for the Advancement of Science. Plant roots and animal guts have evolved specialized cell layers to control mineral nutrient homeostasis. These layers must tolerate the resident microbiota while keeping homeosta... Read More about Coordination between microbiota and root endodermis supports plant mineral nutrient homeostasis.

Persistent millennial-scale climate variability in Southern Europe during Marine Isotope Stage 6 (2020)
Journal Article
Wilson, G. P., Frogley, M. R., Hughes, P. D., Roucoux, K. H., Margari, V., Jones, T. D., Leng, M. J., & Tzedakis, P. C. (2021). Persistent millennial-scale climate variability in Southern Europe during Marine Isotope Stage 6. Quaternary Science Advances, 3, Article 100016. https://doi.org/10.1016/j.qsa.2020.100016

Exploring the mode and tempo of millennial-scale climate variability under evolving boundary conditions can provide insights into tipping points in different parts of the Earth system, and can facilitate a more detailed understanding of climate telec... Read More about Persistent millennial-scale climate variability in Southern Europe during Marine Isotope Stage 6.