Outputs (9)

Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells (2019)
Journal Article
Ahmed, M., Jinks, N., Babaei-Jadidi, R., Kashfi, H., Castellanos-Uribe, M., May, S. T., …Nateri, A. S. (2019). Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells. Cancers, 12(1), Article 106. https://doi.org/10.3390/cancers12010106

Tumour-promoting inflammation is involved in colorectal cancer (CRC) development and therapeutic resistance. However, the antibiotics and antibacterial drugs and signalling that regulate the potency of anticancer treatment upon forced differentiation... Read More about Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells.

A cross-species gene expression marker-based genetic map and QTL analysis in bambara groundnut (2017)
Journal Article
Chai, H., Ho, W., Graham, N., May, S., Massawe, F., & Mayes, S. (2017). A cross-species gene expression marker-based genetic map and QTL analysis in bambara groundnut. Genes, 8(3), https://doi.org/10.3390/genes8020084

Bambara groundnut (Vigna subterranea (L.) Verdc.) is an underutilised legume crop, which has long been recognised as a protein-rich and drought-tolerant crop, used extensively in Sub-Saharan Africa. The aim of the study was to identify quantitative t... Read More about A cross-species gene expression marker-based genetic map and QTL analysis in bambara groundnut.

Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner (2016)
Journal Article
Kroes, A., Broekgaarden, C., Castellanos Uribe, M., May, S., van Loon, J. J., & Dicke, M. (2017). Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner. Oecologia, 183(1), 107-120. https://doi.org/10.1007/s00442-016-3758-3

Plants are commonly attacked by multiple herbivorous species. Yet, little is known about transcriptional patterns underlying plant responses to multiple insect attackers feeding simultaneously. Here, we assessed= transcriptomic responses of Arabidops... Read More about Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner.

Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants (2016)
Journal Article
Eremina, M., Unterholzner, S. J., Rathnayake, A. I., Castellanos, M., Khan, M., Kugler, K. G., …Poppenberger, B. (2016). Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants. Proceedings of the National Academy of Sciences, 113(40), Article E5982-E5991. https://doi.org/10.1073/pnas.1611477113

Brassinosteroids (BRs) are growth-promoting plant hormones that play a role in abiotic stress responses, but molecular modes that enable this activity remain largely unknown. Here we show that BRs participate in the regulation of freezing tolerance.... Read More about Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants.

Teaching Data Science and Cloud Computing in Low and Middle Income Countries (2015)
Journal Article
Shanahan, H., Harrison, A., & May, S. T. (2015). Teaching Data Science and Cloud Computing in Low and Middle Income Countries. Advanced Techniques in Biology & Medicine, 3(3), Article 150. https://doi.org/10.4172/2379-1764.1000150

Large, publicly available data sets present a challenge and an opportunity for researchers based in Low and Middle Income Countries (LMIC). The challenge for these researchers is how they can make use of such data sets given their poor connectivity a... Read More about Teaching Data Science and Cloud Computing in Low and Middle Income Countries.

The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana (2015)
Journal Article
Seguela-Arnaud, M., Smith, C., Castellanos Uribe, M., May, S., Fischl, H., McKenzie, N., & Bevan, M. W. (2015). The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana. BMC Plant Biology, 15(1), Article 215. https://doi.org/10.1186/s12870-015-0592-4

Background: Plant cell walls are dynamic structures involved in all aspects of plant growth, environmental interactions and defense responses, and are the most abundant renewable source of carbon-containing polymers on the planet. To balance rigidity... Read More about The mediator complex subunits MED25/PFT1 and MED8 are required for transcriptional responses to changes in cell wall arabinose composition and glucose treatment in Arabidopsis thaliana.

Pigeons: a novel GUI software for analysing and parsing high density heterologous oligonucleotide microarray probe level data (2014)
Journal Article
Lai, H., May, S., & Mayes, S. (2014). Pigeons: a novel GUI software for analysing and parsing high density heterologous oligonucleotide microarray probe level data. Microarrays, 3(1), https://doi.org/10.3390/microarrays3010001

Genomic DNA-based probe selection by using high density oligonucleotide arrays has recently been applied to heterologous species (Xspecies). With the advent of this new approach, researchers are able to study the genome and transcriptome of a non-mod... Read More about Pigeons: a novel GUI software for analysing and parsing high density heterologous oligonucleotide microarray probe level data.

Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray (2012)
Journal Article
Fabi, J. P., Seymour, G. B., Graham, N. S., Broadley, M. R., May, S., Lajolo, F. M., …Oliveira do Nascimento, J. R. (in press). Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray. BMC Plant Biology, 12, Article 242. https://doi.org/10.1186/1471-2229-12-242

Background Papaya (Carica papaya L.) is a commercially important crop that produces climacteric fruits with a soft and sweet pulp that contain a wide range of health promoting phytochemicals. Despite its importance, little is known about transcrip... Read More about Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray.

Adenosine methylation in Arabidopsis mRNA is associated with the 3? end and reduced levels cause developmental defects (2012)
Journal Article
Bodi, Z., Zhong, S., Mehra, S., Song, J., Graham, N., Li, H., …Fray, R. G. (2012). Adenosine methylation in Arabidopsis mRNA is associated with the 3′ end and reduced levels cause developmental defects. Frontiers in Plant Science, 3(48), Article 48. https://doi.org/10.3389/fpls.2012.00048

We previously showed that the N6-methyladenosine (m6A) mRNA methylase is essential during Arabidopsis thaliana embryonic development. We also demonstrated that this modification is present at varying levels in all mature tissues. However, the require... Read More about Adenosine methylation in Arabidopsis mRNA is associated with the 3? end and reduced levels cause developmental defects.