Outputs (2228)

One Year of Gluten Free Diet Impacts Gut Function and Microbiome in Celiac Disease (2024)
Journal Article
Costigan, C. M., Warren, F. J., Duncan, A. P., Hoad, C. L., Lewis, N., Hill, T., Crooks, C. J., Morgan, P. S., Ciacci, C., Iovino, P., Sanders, D. S., Hildebrand, F., Gowland, P. A., Spiller, R. C., & Marciani, L. (2024). One Year of Gluten Free Diet Impacts Gut Function and Microbiome in Celiac Disease. Clinical Gastroenterology and Hepatology, https://doi.org/10.1016/j.cgh.2024.11.006

BACKGROUND & AIMS: Currently, the main treatment for celiac disease (CD) is gluten free diet (GFD). This observational cohort study investigated the impact of CD and 1 year of GFD on gut function and microbiome.

METHODS: 36 newly diagnosed pat... Read More about One Year of Gluten Free Diet Impacts Gut Function and Microbiome in Celiac Disease.

Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo-controlled Trial in Constipation (2024)
Journal Article
Aliyu, A., Dellschaft, N., Hoad, C., Williams, H., Gaudoin, E., Sulaiman, S., Crooks, C., Gowland, P., Alexia, A., Lange, R., Bois de Fer, B., Corsetti, M., Marciani, L., & Spiller, R. (2024). Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo-controlled Trial in Constipation. Clinical Pharmacology and Therapeutics, https://doi.org/10.1002/cpt.3532

Bisacodyl is a widely used laxative that stimulates both motility and secretion. Our aim was to exploit the unique capabilities of MRI to define bisacodyl's mode of action. Two placebo-controlled cross-over trials were performed, one using a single d... Read More about Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo-controlled Trial in Constipation.

Nanoscale imaging and control of altermagnetism in MnTe (2024)
Journal Article
Amin, O. J., Dal Din, A., Golias, E., Niu, Y., Zakharov, A., Fromage, S. C., Fields, C. J. B., Heywood, S. L., Cousins, R. B., Maccherozzi, F., Krempasky, J., Dil, J. H., Kriegner, D., Kiraly, B., Campion, R. .., Rushforth, A. W., Edmonds, K. .., Dhesi, S. S., Šmejkal, L. .., Jungwirth, T., & Wadley, P. (2024). Nanoscale imaging and control of altermagnetism in MnTe. Nature, 636(8042), 348-353. https://doi.org/10.1038/s41586-024-08234-x

Nanoscale detection and control of the magnetic order underpins a spectrum of condensed-matter research and device functionalities involving magnetism. The key principle involved is the breaking of time-reversal symmetry, which in ferromagnets is gen... Read More about Nanoscale imaging and control of altermagnetism in MnTe.

Polariton-induced transparency in multiple quantum wells probed by time domain Brillouin scattering (2024)
Journal Article
Karzel, M., Samusev, A. K., Linnik, T. L., Littmann, M., Reuter, D., Bayer, M., Scherbakov, A. V., & Akimov, A. V. (2024). Polariton-induced transparency in multiple quantum wells probed by time domain Brillouin scattering. ACS Photonics, https://doi.org/10.1021/acsphotonics.4c01357

The interference of the incident light reflected from the surface of a medium and from a picosecond strain pulse propagating through it results in temporal oscillations of the reflected intensity. This phenomenon, called time-domain Brillouin scatter... Read More about Polariton-induced transparency in multiple quantum wells probed by time domain Brillouin scattering.

Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception (2024)
Journal Article
McGing, J. J., Serres, S., Nicholas, R., Gupta, A., Radford, S. J., Nixon, A. V., Mallinson, J., Bradley, C., Bawden, S., Francis, S. T., Greenhaff, P. L., & Moran, G. W. (in press). Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception. Journal of Crohn's and Colitis,

Background & Objective
IBD fatigue aetiology is poorly understood. This study quantified body composition and physical function alongside proton magnetic resonance imaging (1H MRI) and spectroscopy (31P MRS) measures of organ structure and function... Read More about Deconditioning in quiescent Crohn’s Disease patients with heightened fatigue perception.

Novel Use of Manganese Gluconate as a Marker for Visualization of Tablet Dissolution in the Fed Human Stomach Using Magnetic Resonance Imaging (2024)
Journal Article
Akbar, T., Gershkovich, P., Stamatopoulos, K., Gowland, P., Stolnik, S., Butler, J., & Marciani, L. (2024). Novel Use of Manganese Gluconate as a Marker for Visualization of Tablet Dissolution in the Fed Human Stomach Using Magnetic Resonance Imaging. Molecular Pharmaceutics, https://doi.org/10.1021/acs.molpharmaceut.4c00854

Magnetic resonance imaging (MRI) of dry or solid materials in the gastrointestinal (GI) tract requires the use of contrast agents to enhance visualisation of the dosage forms. In this study, we explore the novel use of manganese gluconate added to ta... Read More about Novel Use of Manganese Gluconate as a Marker for Visualization of Tablet Dissolution in the Fed Human Stomach Using Magnetic Resonance Imaging.

Spin–Phonon Relaxation Dynamics from a Conical Intersection of Trapped Rydberg Ions (2024)
Journal Article
Chaudhary, M., Nath, R., & Li, W. (2024). Spin–Phonon Relaxation Dynamics from a Conical Intersection of Trapped Rydberg Ions. Photonics, 11(12), Article 1135. https://doi.org/10.3390/photonics11121135

Non-adiabatic processes near conical intersections are rooted in the stronger coupling between electronic and nuclear degrees of freedom. Using a system of two trapped Rydberg ions, their high polarizability and strong dipolar interactions allow to f... Read More about Spin–Phonon Relaxation Dynamics from a Conical Intersection of Trapped Rydberg Ions.

Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo-controlled Trial in Constipation (2024)
Journal Article
Aliyu, A., Dellschaft, N., Hoad, C., Williams, H., Gaudoin, E., Sulaiman, S., Crooks, C., Gowland, P., Aran, A., Lange, R., Bois De Fer, B., Corsetti, M., Marciani, L., & Spiller, R. (in press). Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo-controlled Trial in Constipation. Clinical Pharmacology and Therapeutics, https://doi.org/10.1002/cpt.3532

Background and aims: Bisacodyl is a widely used laxative which stimulates both motility and secretion. Our aim was to exploit the unique capabilities of MRI to define bisacodyl’s mode of action.
Methods: 2 placebo-controlled cross-over trials, one... Read More about Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo-controlled Trial in Constipation.

Exact results on the dynamics of the stochastic Floquet-East model (2024)
Journal Article
De Fazio, C., Garrahan, J. P., & Klobas, K. (2024). Exact results on the dynamics of the stochastic Floquet-East model. Journal of Physics A: Mathematical and Theoretical, 57(50), Article 505002. https://doi.org/10.1088/1751-8121/ad8e1c

We introduce a stochastic generalisation of the classical deterministic Floquet-East model, a discrete circuit with the same kinetic constraint as the East model of glasses. We prove exactly that, in the limit of long time and large size, this model... Read More about Exact results on the dynamics of the stochastic Floquet-East model.

New tools for studying planarity in galaxy satellite systems: Milky Way satellite planes are consistent with ΛCDM (2024)
Journal Article
Uzeirbegovic, E., Martin, G., Kaviraj, S., Jackson, R., Kraljic, K., Dubois, Y., Pichon, C., Devriendt, J., Peirani, S., Silk, J., & Yi, S. (2024). New tools for studying planarity in galaxy satellite systems: Milky Way satellite planes are consistent with ΛCDM. Monthly Notices of the Royal Astronomical Society, 535(4), 3775-3784. https://doi.org/10.1093/mnras/stae2632

We introduce a new concept – termed ‘planarity’ – which aims to quantify planar structure in galaxy satellite systems without recourse to the number or thickness of planes. We use positions and velocities from the Gaia EDR3 to measure planarity in Mi... Read More about New tools for studying planarity in galaxy satellite systems: Milky Way satellite planes are consistent with ΛCDM.