Outputs (2)

Optimisation of additively manufactured coiled flow inverters for continuous viral inactivation processes (2024)
Journal Article
Barrera, M. C., Leech, D., Josifovic, A., Tolouei, A., Alford, G., Wallace, M. J., Bennett, N., Wildman, R., Irvine, D. J., Croft, A., Özcan, E., Florence, A. J., Johnston, B., Robertson, J., & Brown, C. J. (2025). Optimisation of additively manufactured coiled flow inverters for continuous viral inactivation processes. Chemical Engineering Research and Design, 213, 126-136. https://doi.org/10.1016/j.cherd.2024.11.040

This article reports the development and utilisation of an adaptive design workflow methodology for use as a platform technology for the printing, testing, and optimisation of biopharmaceutical processing reactors. This design strategy was developed... Read More about Optimisation of additively manufactured coiled flow inverters for continuous viral inactivation processes.

Innate immune cell instruction using micron-scale 3D objects of varied architecture and polymer chemistry: The ChemoArchiChip (2023)
Journal Article
Vassey, M., Ma, L., Kämmerling, L., Mbadugha, C., Trindade, G. F., Figueredo, G. P., Pappalardo, F., Hutchinson, J., Markus, R., Rajani, S., Hu, Q., Winkler, D. A., Irvine, D. J., Hague, R., Ghaemmaghami, A. M., Wildman, R., & Alexander, M. R. (2023). Innate immune cell instruction using micron-scale 3D objects of varied architecture and polymer chemistry: The ChemoArchiChip. Matter, 6(3), 887-906. https://doi.org/10.1016/j.matt.2023.01.002

To design effective immunomodulatory implants, innate immune cell interactions at the surface of biomaterials need to be controlled and understood. The architectural design freedom of two-photon polymerization is used to produce arrays of surface-mou... Read More about Innate immune cell instruction using micron-scale 3D objects of varied architecture and polymer chemistry: The ChemoArchiChip.