Outputs (1477)

Plasma and urine pharmacokinetics of long-acting injectable omeprazole following intramuscular administrations to healthy Thoroughbred horses Short running title: Pharmacokinetics of long-acting injectable omeprazole (2024)
Journal Article
Harding, C., Viljanto, M., Hincks, P., Habershon-Butcher, J., & Paine, S. W. (in press). Plasma and urine pharmacokinetics of long-acting injectable omeprazole following intramuscular administrations to healthy Thoroughbred horses Short running title: Pharmacokinetics of long-acting injectable omeprazole. Journal of Veterinary Pharmacology and Therapeutics,

Omeprazole is a gastric acid secretion inhibitor used as an effective anti-ulcer drug. Based on oral administration studies, its International Screening Limit (ISL) was established in plasma and urine at 1 ng/mL with a Detection Time (DT) of 48 hours... Read More about Plasma and urine pharmacokinetics of long-acting injectable omeprazole following intramuscular administrations to healthy Thoroughbred horses Short running title: Pharmacokinetics of long-acting injectable omeprazole.

Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo (2024)
Journal Article
Wang, L., Zhai, B., Wang, C., Elsheikha, H. M., Guo, H., Zheng, X.-N., Zhou, C., & Zhu, X.-Q. (2024). Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo. Parasites and Vectors, 17(1), Article 522. https://doi.org/10.1186/s13071-024-06610-0

Background: Toxoplasma gondii is an obligate protozoan parasite capable of infecting a wide range of warm-blooded animals and humans. Current treatment options, primarily pyrimethamine and sulfadiazine, have limitations, such as high recurrence rates... Read More about Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo.

Should the equine community be concerned about the emergence of the H5N1 subtype of highly pathogenic avian influenza in US cattle? (2024)
Journal Article
Murcia, P. R., Chambers, T. M., Daly, J. M., Pusterla, N., Damdinjav, B., Ankhanbaatar, U., & Mojsiejczuk, L. (in press). Should the equine community be concerned about the emergence of the H5N1 subtype of highly pathogenic avian influenza in US cattle?. Equine Veterinary Journal, https://doi.org/10.1111/evj.14439

A novel single-tube LAMP-CRISPR/Cas12b method for rapid and visual detection of zoonotic Toxoplasma gondii in the environment (2024)
Journal Article
Liang, Y., Xie, S.-C., Lv, Y.-H., He, Y.-H., Zheng, X.-N., Cong, W., Elsheikha, H. M., & Zhu, X.-Q. (2024). A novel single-tube LAMP-CRISPR/Cas12b method for rapid and visual detection of zoonotic Toxoplasma gondii in the environment. Infectious Diseases of Poverty, 13(1), Article 94. https://doi.org/10.1186/s40249-024-01266-5

Background: Toxoplasma gondii oocysts, excreted in cat feces, pose a significant health risk to humans through contaminated soil and water. Rapid and accurate detection of T. gondii in environmental samples is essential for public health protection.... Read More about A novel single-tube LAMP-CRISPR/Cas12b method for rapid and visual detection of zoonotic Toxoplasma gondii in the environment.

Possible sinoatrial node dysfunction in a 6-month-old domestic shorthair cat (2024)
Journal Article
Hillen, F., & Locquet, L. (2024). Possible sinoatrial node dysfunction in a 6-month-old domestic shorthair cat. Journal of Feline Medicine and Surgery Open Reports, 10(2), https://doi.org/10.1177/20551169241291841

Case summary A six-month-old male entire domestic shorthair cat was presented to the ophthalmology department for nasolacrimal duct cannulation and flushing, and castration under general anaesthesia. On preanaesthetic assessment the cat had a heart r... Read More about Possible sinoatrial node dysfunction in a 6-month-old domestic shorthair cat.

Using Oscillation to Improve the Insertion Depth and Consistency of Hollow Microneedles for Transdermal Insulin Delivery with Mechanistic Insights (2024)
Journal Article
Smith, F., Kotowska, A. M., Fiedler, B., Cerny, E., Cheung, K., Rutland, C. S., Chowdhury, F., Segal, J., Rawson, F. J., & Marlow, M. (2025). Using Oscillation to Improve the Insertion Depth and Consistency of Hollow Microneedles for Transdermal Insulin Delivery with Mechanistic Insights. Molecular Pharmaceutics, 22(1), 316-329. https://doi.org/10.1021/acs.molpharmaceut.4c00942

Microneedles (MNs) offer the potential for discrete and painless transdermal drug delivery, yet poor insertion and dosing consistency have hindered their clinical translation. Specifically, hollow MNs are appropriate for the administration of liquid... Read More about Using Oscillation to Improve the Insertion Depth and Consistency of Hollow Microneedles for Transdermal Insulin Delivery with Mechanistic Insights.

Commentary on the Adaptive Significance of Sociality Around Parturition Events, and Conspecific Support of Parturient Females in Some Social Mammals (2024)
Journal Article
Allen Wild, C., & Yon, L. (2024). Commentary on the Adaptive Significance of Sociality Around Parturition Events, and Conspecific Support of Parturient Females in Some Social Mammals. Animals, 14(24), Article 3601. https://doi.org/10.3390/ani14243601

In recent decades, it has become apparent that during parturition events in a number of social mammals, social support behaviours from group mates can be directed to parturient females (and their newborn neonates). Such behaviour has been documented... Read More about Commentary on the Adaptive Significance of Sociality Around Parturition Events, and Conspecific Support of Parturient Females in Some Social Mammals.

Testosterone variation in a semi-captive population of Asian elephants in Myanmar (2024)
Journal Article
Moullec, H., Berger, V., Santos, D. J., Ukonaho, S., Yon, L., Briga, M., Nyein, U. K., Lummaa, V., & Reichert, S. (2024). Testosterone variation in a semi-captive population of Asian elephants in Myanmar. Conservation Physiology, 12(1), Article coae076. https://doi.org/10.1093/conphys/coae076

Hormones are known to be involved in life-history trade-offs as systemic signals that establish functional links among traits and regulate key behavioural and physiological transitions between states in organisms. Although major functions of many ste... Read More about Testosterone variation in a semi-captive population of Asian elephants in Myanmar.

Genomic characterization and cross-species transmission potential of hedgehog coronavirus (2024)
Journal Article
Cruz, A. V., Santos-Silva, S., Queirós-Reis, L., Rodrigues, C., Soeiro, V., Tarlinton, R. E., & Mesquita, J. R. (2024). Genomic characterization and cross-species transmission potential of hedgehog coronavirus. One Health, 19, Article 100940. https://doi.org/10.1016/j.onehlt.2024.100940

In the 21st century, three betacoronaviruses (SARS-CoV, MERS-CoV and SARS-CoV-2) have emerged in humans worldwide as a result of animal spillover, causing severe respiratory infections and resulting in more than seven million deaths. In 2013, a novel... Read More about Genomic characterization and cross-species transmission potential of hedgehog coronavirus.

Communication skills influence horse owners’ trust in their equine veterinarians (2024)
Journal Article
Rutherford, D. J., & England, J. T. (2024). Communication skills influence horse owners’ trust in their equine veterinarians. Veterinary Record, 195(10), Article e4705. https://doi.org/10.1002/vetr.4705

Background: Trust is an essential component of the relationship between veterinarians and horse owners. To what extent do horse owners consider their vets to be trustworthy, what aspects are important to horse owners when evaluating their vet's trust... Read More about Communication skills influence horse owners’ trust in their equine veterinarians.