Outputs (1403)

Exposure to blue light reduces antimicrobial resistant Pseudomonas aeruginosa isolated from dog ear infections (2024)
Journal Article

Introduction: Pseudomonas aeruginosa is a leading cause of canine otitis externa. Enrofloxacin is often applied topically to treat this condition, although recalcitrant and recurring infections are common. There is evidence that exposure to blue ligh... Read More about Exposure to blue light reduces antimicrobial resistant Pseudomonas aeruginosa isolated from dog ear infections.

Role of pseudotyped viruses in understanding epidemiology, pathogenesis and immunity of viral diseases affecting both horses and humans (2024)
Journal Article

In this review, we explore how pseudotyped viruses (PVs) are being applied to the study of viruses affecting both humans and horses. For the purposes of this review, we define PVs as non-replicative viruses with the core of one virus and the surface... Read More about Role of pseudotyped viruses in understanding epidemiology, pathogenesis and immunity of viral diseases affecting both horses and humans.

UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic (2024)
Journal Article

Background The survival of horses diagnosed with critical colic (requiring referral or euthanasia) relies on rapid and effective decision-making by the owner and veterinary practitioner. Objectives To explore UK horse owners' and veterinary prac... Read More about UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic.

Altered landscape of total RNA, tRNA and sncRNA modifications in the liver and spleen of mice infected by Toxoplasma gondii (2024)
Journal Article

Background Pathogens can impact host RNA modification machinery to establish a favorable cellular environment for their replication. In the present study, we investigated the effect of Toxoplasma gondii infection on host RNA modification profiles... Read More about Altered landscape of total RNA, tRNA and sncRNA modifications in the liver and spleen of mice infected by Toxoplasma gondii.

Comparative cytotoxicity of Acanthamoeba castellanii-derived conditioned medium on human corneal epithelial and stromal cells (2024)
Journal Article

Soluble factors in the secretome of Acanthamoeba castellanii play crucial roles in the pathogenesis of Acanthamoeba keratitis (AK). Investigating the pathological effects of A. castellanii-derived conditioned medium (ACCM) on ocular cells can provide... Read More about Comparative cytotoxicity of Acanthamoeba castellanii-derived conditioned medium on human corneal epithelial and stromal cells.

The importance of 3D fibre architecture in cancer and implications for biomaterial model design (2024)
Journal Article

The need for improved prediction of clinical response is driving the development of cancer models with enhanced physiological relevance. A new concept of ‘precision biomaterials’ is emerging, encompassing patient-mimetic biomaterial models that seek... Read More about The importance of 3D fibre architecture in cancer and implications for biomaterial model design.

Root-soil-microbiome management is key to the success of Regenerative Agriculture (2024)
Journal Article

Building soil health and manipulating the soil microbiome, alongside targeted plant breeding that prioritizes preferential root architectural development, hold the key to the future success of regenerative agriculture. Greater integration is needed b... Read More about Root-soil-microbiome management is key to the success of Regenerative Agriculture.

Multicenter study investigating long‐term survival after synovial lavage of contaminated and septic synovial structures in horses presented to 10 UK referral hospitals (2024)
Journal Article

Objective To report the long-term survival of adult horses that were subjected to synovial lavage for treatment of contaminated and septic synovial structures. Study design Multicenter, prospective observational trial. Animals Horses (n = 24... Read More about Multicenter study investigating long‐term survival after synovial lavage of contaminated and septic synovial structures in horses presented to 10 UK referral hospitals.

Using Object-Oriented Simulation to Assess the Impact of the Frequency and Accuracy of Mobility Scoring on the Estimation of Epidemiological Parameters for Lameness in Dairy Herds (2024)
Journal Article

Mobility scoring data can be used to estimate the prevalence, incidence, and duration of lameness in dairy herds. Mobility scoring is often performed infrequently with variable sensitivity, but how this impacts the estimation of lameness parameters i... Read More about Using Object-Oriented Simulation to Assess the Impact of the Frequency and Accuracy of Mobility Scoring on the Estimation of Epidemiological Parameters for Lameness in Dairy Herds.

The characteristics and prognostic significance of histone H1 expression in breast cancer (2024)
Journal Article

Histone H1 (H.H1) is involved in chromatin organisation and gene regulation and is overexpressed in many malignant tumours, including breast cancer (BC). This study proposed and evaluated the prognostic role of H.H1 expression in BC. H.H1 mRNA exp... Read More about The characteristics and prognostic significance of histone H1 expression in breast cancer.