Outputs (26)

Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation (2023)
Journal Article
Dubern, J. F., Hook, A. L., Carabelli, A. M., Chang, C. Y., Lewis-Lloyd, C. A., Luckett, J. C., Burroughs, L., Dundas, A. A., Humes, D. J., Irvine, D. J., Alexander, M. R., & Williams, P. (2023). Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation. Science Advances, 9(4), Article eadd7474. https://doi.org/10.1126/sciadv.add7474

Innovative approaches to prevent catheter-associated urinary tract infections (CAUTIs) are urgently required. Here, we describe the discovery of an acrylate copolymer capable of resisting single- and multispecies bacterial biofilm formation, swarming... Read More about Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation.

Patient and Public Involvement and Engagement for PhD Students (2023)
Preprint / Working Paper
Gladman, J. R. F., Stocks, J., Phillips, B., Horobin, A., Wragg, A., Mundey, M., Woodcock, R., Braybrooke, R., Junor, A., Hendy, C., Morgan, K., Prior, M., & Humes, D. Patient and Public Involvement and Engagement for PhD Students

This paper aims to provide useful advice regarding the development of skills for patient and public involvement and engagement (PPIE) in research. The authors of this paper comprise experienced PhD supervisors and trainers, researchers leading PPIE a... Read More about Patient and Public Involvement and Engagement for PhD Students.

Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis (2022)
Journal Article
Morton, A. J., Rashid, A., Shim, J. S., West, J., Humes, D. J., & Grainge, M. J. (2023). Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis. ANZ Journal of Surgery, 93(1-2), 42-53. https://doi.org/10.1111/ans.18059

Background: As rectal cancer survival increases, more patients survive with potentially severe, long-term gastrointestinal and genitourinary complications from radiotherapy. The burden of these complications for patients and healthcare services is un... Read More about Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis.

The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy (2022)
Journal Article
Lewis-Lloyd, C. A., Humes, D. J., West, J., Peacock, O., & Crooks, C. J. (2022). The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy. Annals of Surgery, 276(3), E177-E184. https://doi.org/10.1097/SLA.0000000000005563

Objective: To assess the impact of current guidelines by reporting weekly postoperative postdischarge venous thromboembolism (VTE) rates. Summary Background Data: Disparity exists between the postoperative thromboprophylaxis duration colectomy patien... Read More about The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy.

Time Trends in the Incidence Rates of Venous Thromboembolism Following Colorectal Resection by Indication and Operative Technique (2022)
Journal Article
Lewis-Lloyd, C. A., Crooks, C. J., West, J., Peacock, O., & Humes, D. J. (2022). Time Trends in the Incidence Rates of Venous Thromboembolism Following Colorectal Resection by Indication and Operative Technique. Colorectal Disease, 24(11), 1405-1415. https://doi.org/10.1111/codi.16233

Aim
It is important for patient safety to assess if international changes in perioperative care, such as focus on venous thromboembolism (VTE) prevention and minimally invasive surgery have reduced the high post colectomy VTE risks previously report... Read More about Time Trends in the Incidence Rates of Venous Thromboembolism Following Colorectal Resection by Indication and Operative Technique.

Differences in progression by surgical specialty: A national cohort study (2022)
Journal Article
Hope, C., Lund, J., Griffiths, G., & Humes, D. (2022). Differences in progression by surgical specialty: A national cohort study. BMJ Open, 12(2), Article e053391. https://doi.org/10.1136/bmjopen-2021-053391

The aim of surgical training across the 10 surgical specialties is to produce competent day 1 consultants. Progression through training in the UK is assessed by the Annual Review of Competency Progression (ARCP). Objective This study aimed to examine... Read More about Differences in progression by surgical specialty: A national cohort study.

Planned surgery in the COVID-19 pandemic: a prospective cohort study from Nottingham (2021)
Journal Article
Catton, J., Banerjea, A., Gregory, S., Hall, C., Crooks, C., Lewis-Lloyd, C., Marshall, A., & Humes, D. (2021). Planned surgery in the COVID-19 pandemic: a prospective cohort study from Nottingham. Langenbeck's Archives of Surgery, 406, 2469-2477. https://doi.org/10.1007/s00423-021-02207-8

Purpose
Globally planned surgical procedures have been deferred during the current COVID-19 pandemic. The study aimed to report the outcomes of planned urgent and cancer cases during the current pandemic using a multi-disciplinary prioritisation gro... Read More about Planned surgery in the COVID-19 pandemic: a prospective cohort study from Nottingham.

Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation (2021)
Journal Article
Bailey, J. A., Weller, J., Chapman, C., Ford, A., Hardy, K., Oliver, S., Morling, J. R., Simpson, J. A., Humes, D. J., & Banerjea, A. (2021). Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation. BJS Open, 5(2), Article zraa056. https://doi.org/10.1093/bjsopen/zraa056

Background
A novel pathway incorporating faecal immunochemical testing (FIT) for rapid colorectal cancer diagnosis (RCCD) was introduced in 2017. This paper reports on the service evaluation after 2 years of pathway implementation.

Methods
The R... Read More about Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation.

Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study (2021)
Journal Article
Adiamah, A., Ban, L., Otete, H., Crooks, C. J., West, J., & Humes, D. J. (2021). Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study. BJS Open, 5(2), Article zraa073. https://doi.org/10.1093/bjsopen/zraa073

BACKGROUND: The management of perforated diverticular disease has changed in the past 10 years with a move towards less surgical intervention. This population-based cohort study aimed to define the risk of death and readmission following non-operativ... Read More about Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study.

Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessment of patients at high risk of colorectal cancer (2020)
Journal Article
Chapman, C. J., Banerjea, A., Humes, D. J., Allen, J., Oliver, S., Ford, A., Hardy, K., Djedovic, N., Logan, R. F., & Morling, J. R. (2021). Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessment of patients at high risk of colorectal cancer. Clinical Chemistry and Laboratory Medicine, 59(4), 721-728. https://doi.org/10.1515/cclm-2020-1170

Objectives: Currently NICE recommends the use of faecal immunochemical test (FIT) at faecal haemoglobin concentrations (f-Hb) of 10 μg Hb/g faeces to stratify for colorectal cancer (CRC) risk in symptomatic populations. This f-Hb cut-off is advised a... Read More about Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessment of patients at high risk of colorectal cancer.