Outputs (75)

Temporal relationships between systemic lupus erythematosus and comorbidities (2018)
Journal Article
Kuo, C. F., Chou, I.-J., Rees, F., Grainge, M. J., Lanyon, P., Davenport, G., Mallen, C. D., Chung, T. T., Chen, J. S., Zhang, W., & Doherty, M. (2019). Temporal relationships between systemic lupus erythematosus and comorbidities. Rheumatology, 58(5), 840-848. https://doi.org/10.1093/rheumatology/key335

© The Author(s) 2018. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. Objective: To examine the burden of comorbidities prior to and after the diagnosis of SLE and its impact on mortality.... Read More about Temporal relationships between systemic lupus erythematosus and comorbidities.

Interventions for treating wrist fractures in children (Review) (2018)
Journal Article
H.G. Handoll, H., Elliott, J., Iheozor‐Ejiofor, Z., Hunter, J., & Karantana, A. (2018). Interventions for treating wrist fractures in children (Review). Cochrane Database of Systematic Reviews, 2018(12), 1-239. https://doi.org/10.1002/14651858.CD012470.pub2

© 2018 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background: Wrist fractures, involving the distal radius, are the most common fractures in children. Most are buckle fractures, which are stable fractures, unlike greenstick an... Read More about Interventions for treating wrist fractures in children (Review).

Cochrane reviews and dermatological trials outcome concordance: why Core Outcome Sets could make trial results more usable (2018)
Journal Article
Schmitt, J., Lange, T., Kottner, J., Prinsen, C. A. C., Weberschock, T., Hahnel, E., Apfelbacher, C., Brandstetter, S., Dreher, A., Stevens, G., Burden-Teh, E., Rogers, N., Spuls, P., Grainge, M. J., Williams, H. C., Jacobi, L., & Cochrane Skin Core Outcome Set Initiative (CS-COUSIN). (2019). Cochrane reviews and dermatological trials outcome concordance: why Core Outcome Sets could make trial results more usable. Journal of Investigative Dermatology, 139(5), 1045-1053. https://doi.org/10.1016/j.jid.2018.11.019

Evidence-based healthcare requires that relevant outcomes for patients are included in clinical trials which investigating treatment effects allowing subsequent systematic reviews to summarize all relevant evidence to guide clinical practice. Current... Read More about Cochrane reviews and dermatological trials outcome concordance: why Core Outcome Sets could make trial results more usable.

Computer assisted diagnosis techniques (dermoscopy and spectroscopy-based) for diagnosing skin cancer in adults (2018)
Journal Article
Ferrante di Ruffano, L., Takwoingi, Y., Dinnes, J., Chuchu, N., Bayliss, S. E., Davenport, C., Matin, R. N., Godfrey, K., O'Sullivan, C., Gulati, A., Chan, S. A., Durack, A., O'Connell, S., Gardiner, M. D., Bamber, J., Deeks, J. J., & Williams, H. C. (2018). Computer assisted diagnosis techniques (dermoscopy and spectroscopy-based) for diagnosing skin cancer in adults. Cochrane Database of Systematic Reviews, 2018(12), Article CD013186. https://doi.org/10.1002/14651858.CD013186

Background: Early accurate detection of all skin cancer types is essential to guide appropriate management and to improve morbidity and survival. Melanoma and cutaneous squamous cell carcinoma (cSCC) are high‐risk skin cancers which have the potentia... Read More about Computer assisted diagnosis techniques (dermoscopy and spectroscopy-based) for diagnosing skin cancer in adults.

Are environmental factors for atopic eczema in ISAAC Phase Three due to reverse causation? (2018)
Journal Article
Rutter, C., Silverwood, R. J., Williams, H. C., Elwood, P., Asher, I., Garcia-Marcos, L., Strachan, D. P., Pearce, N., Langan, S. M., & ISAAC Phase Three Group. (2019). Are environmental factors for atopic eczema in ISAAC Phase Three due to reverse causation?. Journal of Investigative Dermatology, 139(5), 1023-1036. https://doi.org/10.1016/j.jid.2018.08.035

Some previously described environmental associations for atopic eczema (AE) may be due to reverse causation. We explored the role of reverse causation by comparing individual- and school-level results for multiple AE risk factors.

ISAAC Phase Thre... Read More about Are environmental factors for atopic eczema in ISAAC Phase Three due to reverse causation?.

A trans-atlantic perspective on stagnation in clinical translation of antimicrobial strategies for the control of biomaterial-implant associated infection (2018)
Journal Article
Busscher, H. J., Alt, V., Van Der Mei, H. C., Fagette, P. H., Zimmerli, W., Moriarty, T. F., Parvizi, J., Schmidmaier, G., Raschke, M. J., Gehrke, T., Bayston, R., Baddour, L. M., Winterton, L. C., Darouiche, R. O., & Grainger, D. W. (2019). A trans-atlantic perspective on stagnation in clinical translation of antimicrobial strategies for the control of biomaterial-implant associated infection. ACS Biomaterials Science and Engineering, 5(2), 402-406. https://doi.org/10.1021/acsbiomaterials.8b01071

Current regulatory requirements impede clinical translation and market introduction of many new antimicrobial combination implants and devices, causing unnecessary patient suffering, doctor frustration, and costs to healthcare payers. Regulatory requ... Read More about A trans-atlantic perspective on stagnation in clinical translation of antimicrobial strategies for the control of biomaterial-implant associated infection.

The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation (2018)
Journal Article
Burston, J. J., Valdes, A. M., Woodhams, S. G., Mapp, P. I., Stocks, J., Watson, D. J. G., Gowler, P. R. W., Xu, L., Sagar, D. R., Fernandes, G., Frowd, N., Marshall, L., Zhang, W., Doherty, M., David, D. A., & Chapman, V. (2019). The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation. PAIN, 160(3), 658-669. https://doi.org/10.1097/j.pain.0000000000001445

© 2018 International Association for the Study of Pain. Anxiety and depression are associated with increased pain responses in chronic pain states. The extent to which anxiety drives chronic pain, or vice versa, remains an important question that has... Read More about The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation.

Patients’ understanding of cellulitis and views about how best to prevent recurrent episodes: mixed-methods study in primary and secondary care (2018)
Journal Article
Teasdale, E. J., Lalonde, A., Muller, I., Chalmers, J., Smart, P., Hooper, J., El-Gohary, M., Thomas, K. S., & Santer, M. (2019). Patients’ understanding of cellulitis and views about how best to prevent recurrent episodes: mixed-methods study in primary and secondary care. British Journal of Dermatology, 180(4), 810-820. https://doi.org/10.1111/bjd.17445

Background: Cellulitis is a common painful infection of the skin and underlying tissues that recurs in approximately one-third of cases. The only proven strategy to reduce the risk of recurrence is long-term, low-dose antibiotics. Given current conce... Read More about Patients’ understanding of cellulitis and views about how best to prevent recurrent episodes: mixed-methods study in primary and secondary care.

Thresholds of ultrasound synovial abnormalities for knee osteoarthritis: a cross sectional study in the general population (2018)
Journal Article
Sarmanova, A., Hall, M., Fernandes, G., Valdes, A., Walsh, D., Doherty, M., & Zhang, W. (2019). Thresholds of ultrasound synovial abnormalities for knee osteoarthritis: a cross sectional study in the general population. Osteoarthritis and Cartilage, 27(3), 435-443. https://doi.org/10.1016/j.joca.2018.09.018

Objective

To establish “normal” ranges for synovial thickness and effusion detected by ultrasound (US) and to determine cut-offs associated with knee pain (KP) and radiographic knee osteoarthritis (RKOA) in the community.

Methods

147 women a... Read More about Thresholds of ultrasound synovial abnormalities for knee osteoarthritis: a cross sectional study in the general population.

The red leg dilemma: a scoping review of the challenges of diagnosing lower limb cellulitis (2018)
Journal Article
Patel, M., Kai, J., Lee, S., & Thomas, K. (2019). The red leg dilemma: a scoping review of the challenges of diagnosing lower limb cellulitis. British Journal of Dermatology, 180(5), 993-1000. https://doi.org/10.1111/bjd.17415

Background: Suspected lower limb cellulitis presentations are commonly misdiagnoses, resulting in avoidable antibiotic prescribing or hospital admissions. Understanding the challenges posed in diagnosing cellulitis may help enhance future care.

Ob... Read More about The red leg dilemma: a scoping review of the challenges of diagnosing lower limb cellulitis.