Outputs (25)

The incidence of Kawasaki disease using hospital admissions data for England 2006-2021 (2023)
Journal Article
Odingo, M., Rutter, M., Bowley, J., Peach, E. J., Lanyon, P. C., Grainge, M. J., Stillwell, P., McPhail, S., Bythell, M., Aston, J., Stevens, S., McCormack, R., Brogan, P., & Pearce, F. A. (2023). The incidence of Kawasaki disease using hospital admissions data for England 2006-2021. Rheumatology, 62(9), 3117–3125. https://doi.org/10.1093/rheumatology/kead051

Objective: To describe the incidence of Kawasaki Disease (kDa) between 2006 and 2021 in England. Methods: We identified all cases in hospital episode statistics with an ICD-10 diagnostic code M303 (for kDa) between 1 April 2006 and 31 March 2021. We... Read More about The incidence of Kawasaki disease using hospital admissions data for England 2006-2021.

Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination (2022)
Journal Article
Gumber, L., Gomez, N., Hopkins, G., Tucis, D., Bartlett, L., Ayling, K., Vedhara, K., Steers, G., Chakravorty, M., Rutter, M., Jackson, H., Tighe, P., Ferraro, A., Power, S., Pradère, M.-J., Onion, D., Lanyon, P. C., Pearce, F. A., & Fairclough, L. (2023). Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination. Rheumatology, 62(6), 2294-2303. https://doi.org/10.1093/rheumatology/keac574

Objectives: COVID-19 vaccine responses in rare autoimmune rheumatic diseases (RAIRD) remain poorly understood, in particular there is little known about whether people develop effective T-cell responses. We conducted a prospective cohort study to eva... Read More about Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination.

COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis (2022)
Journal Article
Cordtz, R., Kristensen, S., Westermann, R., Duch, K., Pearce, F., Lindhardsen, J., Torp-Pedersen, C., Andersen, M. P., & Dreyer, L. (2023). COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis. Rheumatology, 62(1), 77-88. https://doi.org/10.1093/rheumatology/keac241

Objectives: The objectives of this study were to investigate the incidence of COVID-19 hospitalization in unvaccinated and vaccinated patients with RA compared with matched controls, and in patients with RA according to DMARD treatment.

Methods: T... Read More about COVID-19 infection and hospitalization risk according to vaccination status and DMARD treatment in patients with rheumatoid arthritis.

COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project (2021)
Journal Article
Rutter, M., Lanyon, P. C., Grainge, M. J., Hubbard, R., Peach, E., Bythell, M., Stilwell, P., Aston, J., Stevens, S., & Pearce, F. A. (2022). COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project. Rheumatology, 61(8), 3161-3171. https://doi.org/10.1093/rheumatology/keab794

Objectives: To calculate the rates of COVID-19 infection and COVID-19-related death among people with rare autoimmune rheumatic diseases (RAIRD) during the first wave of the COVID-19 pandemic in England compared to the general population.

Methods... Read More about COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project.

Estimating the clinical prevalence of Wilson’s disease in the UK (2021)
Journal Article
Wijayasiri, P., Hayre, J., Nicholson, E. S., Kaye, P., Wilkes, E. A., Evans, J., Aithal, G. P., Jones, G., Pearce, F., & Aravinthan, A. D. (2021). Estimating the clinical prevalence of Wilson’s disease in the UK. JHEP Reports, 3(5), Article 100329. https://doi.org/10.1016/j.jhepr.2021.100329

Background and Aim
The clinical prevalence of Wilson’s disease (WD) in the UK remains unknown. The estimated genetic prevalence in the UK, 142/million, is higher than the clinical prevalence (15/million) reported in other European studies. The aim o... Read More about Estimating the clinical prevalence of Wilson’s disease in the UK.

A Systematic Review and Meta-Analysis of the Incidence Rate of Takayasu Arteritis (2021)
Journal Article
Grainge, M. J., Rutter, M., Lanyon, P. C., Pearce, F. A., Bowley, J., & Claringburn, T. (2021). A Systematic Review and Meta-Analysis of the Incidence Rate of Takayasu Arteritis. Rheumatology, 60(11), 4982-4990. https://doi.org/10.1093/rheumatology/keab406

Objectives:
Takayasu arteritis (TAK), is a rare autoimmune rheumatic disease causing large vessel vasculitis. Onset is typically between the ages of 20-30. It is associated with substantial morbidity and mortality, notably due to its effects on the... Read More about A Systematic Review and Meta-Analysis of the Incidence Rate of Takayasu Arteritis.

Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink (2021)
Journal Article
Peach, E., Pearce, F., Gibson, J., Cooper, A., Chen, L.-C., & Knaggs, R. (2021). Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink. American Journal of Epidemiology, 190(7), 1324-1331. https://doi.org/10.1093/aje/kwab042

Self-controlled study designs can be used to assess the association between exposures and acute outcomes while controlling for important confounders. Using routinely collected health data, a self-controlled case series design was used to investigate... Read More about Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink.

Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink (2021)
Journal Article
Peach, E. J., Pearce, F. A., Gibson, J., Andrew J. Cooper, A. J., Chen, L.-C., & Knaggs, R. D. (2021). Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink. American Journal of Epidemiology, 190(7), 1324-1331. https://doi.org/10.1093/aje/kwab042

Self-controlled study designs can be used to assess the association between exposures and acute outcomes while controlling for important confounders. Using routinely collected health data, a self-controlled case series design was used to investigate... Read More about Opioids and the risk of fracture: a self-controlled case series study in the Clinical Practice Research Datalink.

Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis (2021)
Journal Article
Johnston, P. I., Wright, S. W., Orr, M., Pearce, F. A., Stevens, J. W., Hubbard, R. B., & Collini, P. J. (2021). Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis. AIDS, 35(6), 957-970. https://doi.org/10.1097/QAD.0000000000002815

Objective and design: People living with HIV (PLH) suffer disproportionately from the chronic diseases exacerbated by smoking tobacco. We performed a systematic review and meta-analysis to establish the relative prevalence of smoking among PLH.

M... Read More about Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis.

BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK (2020)
Journal Article
Pearce, F. A., Rutter, M., Sandhu, R., Batten, R. L., Garner, R., Little, J., Narayan, N., Sharp, C. A., Bruce, I. N., Erb, N., Griffiths, B., Guest, H., Macphie, E., Packham, J., Hiley, C., Obrenovic, K., Rivett, A., Gordon, C., & Lanyon, P. C. (2021). BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK. Rheumatology, 60(3), 1480-1490. https://doi.org/10.1093/rheumatology/keaa759

Objectives: To assess the baseline care provided to patients with SLE attending UK Rheumatology units, audited against standards derived from the recently published BSR guideline for the management of adults with SLE, the NICE technology appraisal fo... Read More about BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK.