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The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review (2023)
Journal Article
Phillips, O., Baguley, D., Pearson, S., & Akeroyd, M. A. (2023). The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review. Journal of Cancer Survivorship, 17(1), 40-58. https://doi.org/10.1007/s11764-022-01314-9

Purpose: To elucidate the long-term impacts of hearing loss, tinnitus and balance in people living with and beyond cancer (LWBC) treated with platinum-based chemotherapy (PBCT). Methods: A literature search was conducted between March and June 2022 u... Read More about The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review.

A Systematic Review and Meta-Analysis of Extended High-Frequency Hearing Thresholds in Tinnitus With a Normal Audiogram (2022)
Journal Article
Jafari, Z., Baguley, D., Kolb, B. E., & Mohajerani, M. H. (2022). A Systematic Review and Meta-Analysis of Extended High-Frequency Hearing Thresholds in Tinnitus With a Normal Audiogram. Ear and Hearing, 43(6), 1643-1652. https://doi.org/10.1097/AUD.0000000000001229

OBJECTIVES: Current evidence supports the growing application of extended high-frequency (EHF: 9 to 20 kHz) audiometry in hearing research, which likely results from the high vulnerability of this frequency region to damage induced by known auditory... Read More about A Systematic Review and Meta-Analysis of Extended High-Frequency Hearing Thresholds in Tinnitus With a Normal Audiogram.

Consensus Definition of Misophonia: A Delphi Study (2022)
Journal Article
Swedo, S., Baguley, D. M., Denys, D., Dixon, L. J., Erfanian, M., Fioretti, A., …Raver, S. M. (2022). Consensus Definition of Misophonia: A Delphi Study. Frontiers in Neuroscience, 16, Article 841816. https://doi.org/10.3389/fnins.2022.841816

Misophonia is a disorder of decreased tolerance to specific sounds or their associated stimuli that has been characterized using different language and methodologies. The absence of a common understanding or foundational definition of misophonia hind... Read More about Consensus Definition of Misophonia: A Delphi Study.

An Exploratory Investigation of Pupillometry As a Measure of Tinnitus Intrusiveness on a Test of Auditory Short-Term Memory (2022)
Journal Article
Barrett, D. J., Souto, D., Pilling, M., & Baguley, D. M. (2022). An Exploratory Investigation of Pupillometry As a Measure of Tinnitus Intrusiveness on a Test of Auditory Short-Term Memory. Ear and Hearing, 43(5), 1540-1548. https://doi.org/10.1097/AUD.0000000000001214

Objectives: The purpose of the current study was to investigate the potential of pupillometry to provide an objective measure of competition between tinnitus and external sounds during a test of auditory short-term memory. Design: Twelve participants... Read More about An Exploratory Investigation of Pupillometry As a Measure of Tinnitus Intrusiveness on a Test of Auditory Short-Term Memory.

Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study (2021)
Journal Article
Maxwell, K., Robinson, J. M., Hoffmann, I., Hou, H. J., Searchfield, G., Baguley, D. M., …Anderson, J. J. (2021). Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study. Otology and Neurotology, 42(10), e1625-e1633. https://doi.org/10.1097/mao.0000000000003369

Objective: To evaluate the safety and exploratory efficacy of intratympanic administration of OTO-313 in patients with tinnitus. Study Design: Single intratympanic injection of OTO-313 evaluated in a randomized, double-blind, placebo-controlle... Read More about Intratympanic Administration of OTO-313 Reduces Tinnitus in Patients With Moderate to Severe, Persistent Tinnitus: A Phase 1/2 Study.

Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study (2021)
Journal Article
Evans, R. A., McAuley, H., Harrison, E. M., Shikotra, A., Singapuri, A., Sereno, M., …Zongo, O. (2021). Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study. Lancet Respiratory Medicine, 9(11), 1275-1287. https://doi.org/10.1016/S2213-2600%2821%2900383-0

Background: The impact of COVID-19 on physical and mental health and employment after hospitalisation with acute disease is not well understood. The aim of this study was to determine the effects of COVID-19-related hospitalisation on health and empl... Read More about Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis (2021)
Journal Article
Garinis, A. C., Poling, G. L., Rubenstein, R. C., Konrad-Martin, D., Hullar, T. E., Baguley, D. M., …Brewer, C. C. (2021). Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis. American Journal of Audiology, 30(3S), 800-809. https://doi.org/10.1044/2021_aja-21-00031

Purpose Specific classes of antibiotics, such as aminoglycosides, have well-established adverse events producing permanent hearing loss, tinnitus, and balance and/or vestibular problems (i.e., ototoxicity). Although these antibiotics are frequently u... Read More about Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis.

The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study (2021)
Journal Article
Pearson, S. E., Caimino, C., Shabbir, M., & Baguley, D. M. (2022). The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study. Journal of Cancer Survivorship, 16, 976-987. https://doi.org/10.1007/s11764-021-01089-5

Purpose: This study aimed to explore the burden of inner ear damage (ototoxicity) on adults living with and beyond cancer treated with chemotherapy and the impact on their quality of life (QoL). Furthermore, this study aimed to explore patient awaren... Read More about The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study.

Investigating tinnitus subgroups based on hearing-related difficulties (2021)
Journal Article
Beukes, E. W., Baguley, D. M., Manchaiah, V., Andersson, G., Allen, P. M., Kaldo, V., …Maidment, D. W. (2021). Investigating tinnitus subgroups based on hearing-related difficulties. International Journal of Clinical Practice, 75(10), Article e14684. https://doi.org/10.1111/ijcp.14684

Purpose Meaningfully grouping individuals with tinnitus who share a common characteristics (ie, subgrouping, phenotyping) may help tailor interventions to certain tinnitus subgroups and hence reduce outcome variability. The purpose of this study was... Read More about Investigating tinnitus subgroups based on hearing-related difficulties.

Preferential Cochleotoxicity of Cisplatin (2021)
Journal Article
Prayuenyong, P., Baguley, D. M., Kros, C. J., & Steyger, P. S. (2021). Preferential Cochleotoxicity of Cisplatin. Frontiers in Neuroscience, 15, Article 695268. https://doi.org/10.3389/fnins.2021.695268

Cisplatin-induced ototoxicity in humans is more predominant in the cochlea than in the vestibule. Neither definite nor substantial vestibular dysfunction after cisplatin treatment has been consistently reported in the current literature. Inner ear ha... Read More about Preferential Cochleotoxicity of Cisplatin.