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Outputs (488)

Expression of voltage-dependent potassium channels in first trimester human placentae (2014)
Journal Article
Mistry, H. D., Kurlak, L., Whitley, G. S., Cartwright, J. E., Broughton Pipkin, F., & Tribe, R. M. (2014). Expression of voltage-dependent potassium channels in first trimester human placentae. Placenta, 35(5), https://doi.org/10.1016/j.placenta.2014.02.008

Potassium channel α-subunits encoded by KCNQ1-5 genes form voltage-dependent channels (Kv7), modulated by KCNE1-5 encoded accessory proteins. The aim was to determine KCNQ and KCNE mRNA expression and assess protein expression/localisation of the KCN... Read More about Expression of voltage-dependent potassium channels in first trimester human placentae.

Antepartum fetal health (2014)
Journal Article
Tsang, J. C., Tsang, J. C. K., & Jones, N. W. (2014). Antepartum fetal health. Obstetrics, Gynaecology and Reproductive Medicine, 24(3), 80-84. https://doi.org/10.1016/j.ogrm.2014.01.002

Delivery of a healthy full term baby following an uneventful antenatal period occurs in the majority of pregnancies. These are classified as a low-risk pregnancy group. There are, however, some pregnancies that are complicated due to maternal or feta... Read More about Antepartum fetal health.

Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis (2014)
Journal Article
Smyth, A. R., & Bhatt, J. (2014). Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. Cochrane Library, https://doi.org/10.1002/14651858.CD002009.pub5

Background: People with cystic fibrosis, who are chronically colonised with the organism Pseudomonas aeruginosa, often require multiple courses of intravenous aminoglycoside antibiotics for the management of pulmonary exacerbations. The properties of... Read More about Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis.

Effect of ethnicity on live birth rates after in vitro fertilisation or intracytoplasmic sperm injection treatment (2014)
Journal Article
Jayaprakasan, K., Pandian, D., Hopkisson, J., Campbell, B., & Maalouf, W. (2014). Effect of ethnicity on live birth rates after in vitro fertilisation or intracytoplasmic sperm injection treatment. BJOG: An International Journal of Obstetrics and Gynaecology, 121(3), https://doi.org/10.1111/1471-0528.12504

Objective
To assess the relationship between the ethnicity of women and the clinical success of in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) treatment.
Design
Observational cohort study.
Setting
Nottingham University R... Read More about Effect of ethnicity on live birth rates after in vitro fertilisation or intracytoplasmic sperm injection treatment.

Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding on diet-induced thermogenesis in adult mouse offspring (2014)
Journal Article
Sellayah, D., Dib, L., Anthony, F., Watkins, A., Fleming, T., Hanson, M., & Cagampang, F. (2014). Effect of maternal protein restriction during pregnancy and postweaning high-fat feeding on diet-induced thermogenesis in adult mouse offspring. European Journal of Nutrition, 53(7), 1523-1531. https://doi.org/10.1007/s00394-014-0657-4

Overcoming multiple drug resistance mechanisms in medulloblastoma (2014)
Journal Article
Othman, R., Coyle, B., Kimishi, I., Bradshaw, T. D., Storer, L., Korshunov, A., Pfister, S., Grundy, R., & Kerr, I. D. (2014). Overcoming multiple drug resistance mechanisms in medulloblastoma. Acta Neuropathologica Communications, 2(1), Article 57. https://doi.org/10.1186/2051-5960-2-57

© 2014 Othman et al.; licensee BioMed Central Ltd. Introduction: Medulloblastoma (MB) is the most common malignant paediatric brain tumour. Recurrence and progression of disease occurs in 15-20% of standard risk and 30-40% of high risk patients. We a... Read More about Overcoming multiple drug resistance mechanisms in medulloblastoma.

RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells (2014)
Journal Article
Lagah, S., Tan, I.-L., Radhakrishnan, P., Hirst, R. A., Ward, J. H., O'Callaghan, C., Smith, S. J., Stevens, M. F., Grundy, R. G., & Rahman, R. (2014). RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells. PLoS ONE, 9(1), Article e86187. https://doi.org/10.1371/journal.pone.0086187

Background
Telomeric 3’ overhangs can fold into a four-stranded DNA structure termed G-quadruplex (G4), a formation which inhibits telomerase. As telomerase activation is crucial for telomere maintenance in most cancer cells, several classes of G4... Read More about RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells.

Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study (2014)
Journal Article
Hurley, M., McKeever, T. M., Prayle, A. P., Smyth, A. R., & Fogarty, A. W. (2014). Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study. Journal of Cystic Fibrosis, 13(4), https://doi.org/10.1016/j.jcf.2013.12.002

Background: It is unclear why cystic fibrosis (CF) survival has improved. We wished to quantify increases in CF median age of death in the context of general population survival improvement.
Method: Death registration data analysis (US, England & Wa... Read More about Rate of improvement of CF life expectancy exceeds that of general population: observational death registration study.