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Sox-positive cell population in the adult cerebellum increases upon tissue degeneration (2021)
Journal Article
Salih, S., Nizamudeen, Z. A., De Melo, N., Chakrabarti, L., & Sottile, V. (2022). Sox-positive cell population in the adult cerebellum increases upon tissue degeneration. Experimental Neurology, 348, Article 113950. https://doi.org/10.1016/j.expneurol.2021.113950

Adult neurogenesis is well-described in the subventricular and subgranular zones of the mammalian brain. Recent observations that resident glia express stem cell markers in some areas of the brain not traditionally associated with neurogenesis hint t... Read More about Sox-positive cell population in the adult cerebellum increases upon tissue degeneration.

Diagnostic Armamentarium of Infectious Keratitis: A Comprehensive Review (2021)
Journal Article
Ting, D. S. J., Gopal, B. P., Deshmukh, R., Seitzman, G. D., Said, D. G., & Dua, H. S. (2022). Diagnostic Armamentarium of Infectious Keratitis: A Comprehensive Review. Ocular Surface, 23, 27-39. https://doi.org/10.1016/j.jtos.2021.11.003

Infectious keratitis (IK) represents the leading cause of corneal blindness worldwide, particularly in developing countries. A good outcome of IK is contingent upon timely and accurate diagnosis followed by appropriate interventions. Currently, IK is... Read More about Diagnostic Armamentarium of Infectious Keratitis: A Comprehensive Review.

Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA (2021)
Journal Article
Wang, Y., Meng, X., Wang, A., Xie, X., Pan, Y., Johnston, S. C., …CHANCE-2 Investigators. (2021). Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA. New England Journal of Medicine, 385(27), 2520-2530. https://doi.org/10.1056/NEJMoa2111749

BACKGROUND Comparisons between ticagrelor and clopidogrel for the secondary prevention of stroke in CYP2C19 loss-of-function carriers have not been extensively performed. METHODS We conducted a randomized, double-blind, placebo-controlled trial at 20... Read More about Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA.

Guillain–Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination (2021)
Journal Article
Allen, C. M., Ramsamy, S., Tarr, A. W., Tighe, P. J., Irving, W. L., Tanasescu, R., & Evans, J. R. (2021). Guillain–Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination. Annals of Neurology, 90(2), 315-318. https://doi.org/10.1002/ana.26144

Although SARS-CoV-2 vaccines are very safe, we report 4 cases of the bifacial weakness with paresthesias variant of Guillain–Barré syndrome (GBS) occurring within 3 weeks of vaccination with the Oxford–AstraZeneca SARS-CoV-2 vaccine. This rare neurol... Read More about Guillain–Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination.

A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial (2021)
Journal Article
Shaw, D., Martin, M. J., Sutherland, L., Shaw, K., Parrish, C., Singleton, N., …Harrison, T. (2021). A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial. Respirology, 26(7), 666-672. https://doi.org/10.1111/resp.14055

Background and objective: Fractional exhaled nitric oxide (FeNO) is a non-invasive biomarker that reflects IL-4/IL-13 production and therefore represents T2 allergic inflammation. FeNO has previously been used to guide inhaled corticosteroid (ICS) tr... Read More about A low exhaled nitric oxide level excludes a short-term benefit from inhaled corticosteroids in suspected asthma: A randomized placebo-controlled trial.

Opioid prescription at postoperative discharge: a retrospective observational cohort study (2021)
Journal Article
Daliya, P., Adiamah, A., Roslan, F., Theophilidou, E., Knaggs, R., Levy, N., & Lobo, D. (2021). Opioid prescription at postoperative discharge: a retrospective observational cohort study. Anaesthesia, 76(10), 1367-1376. https://doi.org/10.1111/anae.15460

Opioid misuse is now considered a major public health epidemic in North America, with substantial social and financial consequences. As well as socio-economic and commercial drivers, modifiable risk-factors that have resulted in this crisis have been... Read More about Opioid prescription at postoperative discharge: a retrospective observational cohort study.

A brief acceptance and commitment intervention for work-related stress and burnout amongst frontline homelessness staff: A single case experimental design series (2021)
Journal Article
Reeve, A., Moghaddam, N., Tickle, A., & Young, D. (2021). A brief acceptance and commitment intervention for work-related stress and burnout amongst frontline homelessness staff: A single case experimental design series. Clinical Psychology and Psychotherapy, 28(5), 1001-1019. https://doi.org/10.1002/cpp.2555

Purpose Recent intervention research for burnout amongst those working in health and social care contexts has found acceptance and commitment therapy (ACT) interventions to be of use but has provided less clarity on the role of psychological flexibi... Read More about A brief acceptance and commitment intervention for work-related stress and burnout amongst frontline homelessness staff: A single case experimental design series.

Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery (2021)
Journal Article
Lizio, M. G., Liao, Z., Shipp, D. W., Boitor, R., Mihai, R., Sharp, J. S., …Notingher, I. (2021). Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery. Biomedical Optics Express, 12(2), 940-954. https://doi.org/10.1364/boe.411648

The standard treatment for breast cancer is surgical removal mainly through breast conserving surgey (BCS). We developed a new technique based on auto-fluorescence (AF) spectral imaging and Raman spectroscopy for fast intraoperative assessment of exc... Read More about Combined total internal reflection AF spectral-imaging and Raman spectroscopy for fast assessment of surgical margins during breast cancer surgery.