Do Mutations Turn p53 into an Oncogene?
(2019)
Journal Article
Pitolli, C., Wang, Y., Mancini, M., Shi, Y., Melino, G., & Amelio, I. (2019). Do Mutations Turn p53 into an Oncogene?. International Journal of Molecular Sciences, 20(24), https://doi.org/10.3390/ijms20246241
Outputs (16)
p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms (2019)
Journal Article
Pitolli, C., Wang, Y., Candi, E., Shi, Y., Melino, G., & Amelio, I. (2019). p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms. Cancers, 11(12), https://doi.org/10.3390/cancers11121983© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The tumor suppressor p53 regulates different cellular pathways involved in cell survival, DNA repair, apoptosis, and senescence. However, according to an increasing number of studies, the p53-... Read More about p53-Mediated Tumor Suppression: DNA-Damage Response and Alternative Mechanisms.
The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress (2019)
Journal Article
Al-Ghafari, A., Elmorsy, E., Fikry, E., Alrowaili, M., & Carter, W. G. (2019). The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress. PLoS ONE, 14(11), https://doi.org/10.1371/journal.pone.0225341The heavy metals (HMs) lead and cadmium are persistent environmental pollutants capable of inducing ill-health in exposed individuals. One of the primary sites of accumulation and potential damage from HMs is bone, and we therefore examined the acute... Read More about The heavy metals lead and cadmium are cytotoxic to human bone osteoblasts via induction of redox stress.
Move-It ???: Digital worksite exercise in China - outcome and process evaluation (2019)
Conference Proceeding
Blake, H., Lai, B., Houdmont, J., & Griffiths, A. (2019). Move-It ???: Digital worksite exercise in China - outcome and process evaluation. In 5th International Clinical Trials Methodology Conference (ICTMC 2019) Book of Abstracts
Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging (2019)
Journal Article
Chou, I., Tanasescu, R., Mougin, O. E., Gowland, P. A., Tench, C. R., Whitehouse, W. P., …Constantinescu, C. S. (2019). Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging. Scientific Reports, 9, Article 14378. https://doi.org/10.1038/s41598-019-50928-0Whether the integrity of normal-appearing white matter (NAWM) is preserved in neuromyelitis optica spectrum disorders (NMOSD) is open to debate. To examine whether the tissue integrity of NAWM in NMOSD is compromised compared to that in healthy contr... Read More about Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging.
Antenatal infection and intraventricular hemorrhage in preterm infants: a meta-analysis (2019)
Journal Article
Huang, J., Meng, J., Choonara, I., Xiong, T., Wang, Y., Wang, H., …Mu, D. (2019). Antenatal infection and intraventricular hemorrhage in preterm infants: a meta-analysis. Medicine, 98(31), Article e16665. https://doi.org/10.1097/md.0000000000016665
Clinical update on head and neck cancer: molecular biology and ongoing challenges (2019)
Journal Article
Alsahafi, E., Begg, K., Amelio, I., Raulf, N., Lucarelli, P., Sauter, T., & Tavassoli, M. (2019). Clinical update on head and neck cancer: molecular biology and ongoing challenges. Cell Death and Disease, 10(8), Article 540. https://doi.org/10.1038/s41419-019-1769-9
Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis (2019)
Journal Article
Li, Y., Reeves, R. M., Wang, X., Bassat, Q., Brooks, W. A., Cohen, C., …Zar, H. J. (2019). Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis. Lancet Global Health, 7(8), e1031-e1045. https://doi.org/10.1016/s2214-109x%2819%2930264-5Background: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (
Collagen (XI) alpha-1 chain (COL11A1) is an independent prognostic factor in breast ductal carcinoma in situ (2019)
Journal Article
Toss, M. S., Miligy, I. M., Gorringe, K. L., Aleskandarany, M. A., Alkawaz, A., Mittal, K., …Rakha, E. A. (2019). Collagen (XI) alpha-1 chain (COL11A1) is an independent prognostic factor in breast ductal carcinoma in situ. Modern Pathology,Collagen11A1 (COL11A1) is a fibrillary type collagen constituting a minor component of the extracellular matrix and plays role in tissue tensile strength. Overexpression of COL11A1 expression is associated with aggressive behavior and poor outcome in... Read More about Collagen (XI) alpha-1 chain (COL11A1) is an independent prognostic factor in breast ductal carcinoma in situ.
Switching from linear to macrocyclic gadolinium‐based contrast agents halts the relative T 1 ‐Weighted signal increase in deep gray matter of children with brain tumors: A retrospective study (2019)
Journal Article
Rowe, S. K., Rodriguez, D., Cohen, E., Grundy, R., Morgan, P. S., Jaspan, T., & Dineen, R. A. (2019). Switching from linear to macrocyclic gadolinium‐based contrast agents halts the relative T 1 ‐Weighted signal increase in deep gray matter of children with brain tumors: A retrospective study. Journal of Magnetic Resonance Imaging, https://doi.org/10.1002/jmri.26831Background Studies have shown signal intensity (SI) changes in the brains of children exposed to repeated doses of a gadolinium‐based contrast agent (GBCA). Hypothesis The trajectory of changes in relative dentate nucleus (DN) and globus pal... Read More about Switching from linear to macrocyclic gadolinium‐based contrast agents halts the relative T 1 ‐Weighted signal increase in deep gray matter of children with brain tumors: A retrospective study.