Outputs (27)

Real world evidence for public health decision-making on vaccination policies: perspectives from an expert roundtable (2023)
Journal Article
de Waure, C., Gärtner, B. C., Lopalco, P. L., Puig-Barbera, J., & Nguyen-Van-Tam, J. S. (2024). Real world evidence for public health decision-making on vaccination policies: perspectives from an expert roundtable. Expert Review of Vaccines, 23(1), 27-38. https://doi.org/10.1080/14760584.2023.2290194

INTRODUCTION: Influenza causes significant morbidity and mortality, but influenza vaccine uptake remains below most countries' targets. Vaccine policy recommendations vary, as do procedures for reviewing and appraising the evidence. AREAS COVERED: Du... Read More about Real world evidence for public health decision-making on vaccination policies: perspectives from an expert roundtable.

Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity (2023)
Journal Article
Swets, M. C., Kerr, S., Scott-Brown, J., Brown, A. B., Gupta, R., Millar, J. E., Spata, E., McCurrach, F., Bretherick, A. D., Docherty, A., Harrison, D., Rowan, K., Young, N., Groeneveld, G. H., Dunning, J., Nguyen-Van-Tam, J. S., Openshaw, P., Horby, P. W., Harrison, E., Staplin, N., …ISARIC4C Investigators. (2023). Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity. Nature Communications, 14(1), Article 7374. https://doi.org/10.1038/s41467-023-42205-6

Choosing optimal outcome measures maximizes statistical power, accelerates discovery and improves reliability in early-phase trials. We devised and evaluated a modification to a pragmatic measure of oxygenation function, the S/F ratio. Because of the... Read More about Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity.

Synthesis and Characterization of Doped Magnesium Hydroxide for Medium Heat Storage Application (2023)
Journal Article
Albeladi, N., Kur, A., Mokaya, R., Darkwa, J., Roger-Lund, S., Worall, M., Calautit, J., & Boukhanouf, R. (2023). Synthesis and Characterization of Doped Magnesium Hydroxide for Medium Heat Storage Application. Materials, 16(18), Article 6296. https://doi.org/10.3390/ma16186296

The amount of waste heat generated annually in the UK exceeds the total annual electricity demand. Hence, it is crucial to effectively harness all available sources of waste heat based on their varying temperatures. Through suitable technologies, a s... Read More about Synthesis and Characterization of Doped Magnesium Hydroxide for Medium Heat Storage Application.

Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease (2023)
Journal Article
Gbinigie, O., Ogburn, E., Allen, J., Dorward, J., Dobson, M., Madden, T.-A., Yu, L.-M., Lowe, D. M., Rahman, N., Petrou, S., Richards, D., Hood, K., Patel, M., Saville, B. R., Marion, J., Holmes, J., Png, M. E., Hayward, G., Lown, M., Harris, V., …Butler, C. C. (2023). Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease. BMJ Open, 13(8), Article e069176. https://doi.org/10.1136/bmjopen-2022-069176

Introduction: There is an urgent need to determine the safety, effectiveness and cost-effectiveness of novel antiviral treatments for COVID-19 in vaccinated patients in the community at increased risk of morbidity and mortality from COVID-19.

Met... Read More about Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease.

A simple, sustainable route to flexible microporous carbon cloth for energy storage applications (2023)
Journal Article
Alkhaldi, T., Blankenship, L. S., & Mokaya, R. (2023). A simple, sustainable route to flexible microporous carbon cloth for energy storage applications. Materials Advances, 4(16), 3559-3571. https://doi.org/10.1039/d3ma00157a

Activated carbon cloth (ACC) has the potential to be extremely useful in gas capture and storage applications as it combines high porosity, robustness, and flexibility with ease of handling. While it has been produced by a few researchers, the synthe... Read More about A simple, sustainable route to flexible microporous carbon cloth for energy storage applications.

Solvothermal synthesis of organoclay/Cu-MOF composite and its application in film modified GCE for simultaneous electrochemical detection of deoxyepinephrine, acetaminophen and tyrosine (2023)
Journal Article
Mouafo-Tchinda, E., Kemmegne-Mbouguen, J. C., Nanseu-Njiki, C. P., Langmi, H. W., Kowenje, C., Musyoka, N. M., & Mokaya, R. (2023). Solvothermal synthesis of organoclay/Cu-MOF composite and its application in film modified GCE for simultaneous electrochemical detection of deoxyepinephrine, acetaminophen and tyrosine. RSC Advances, 13(30), 20816-20829. https://doi.org/10.1039/d3ra03850e

An organoclay/copper-based metal-organic framework (MOF) composite was synthesized using a solvothermal method by growing a Cu-BTC (copper(ii) benzene-1,3,5-tricarboxylate) MOF from a mixture of the MOF precursor solution in which various amounts of... Read More about Solvothermal synthesis of organoclay/Cu-MOF composite and its application in film modified GCE for simultaneous electrochemical detection of deoxyepinephrine, acetaminophen and tyrosine.

Risk prediction of covid-19 related death or hospital admission in adults testing positive for SARS-CoV-2 infection during the omicron wave in England (QCOVID4): cohort study (2023)
Journal Article
Hippisley-Cox, J., Khunti, K., Sheikh, A., Nguyen-Van-Tam, J. S., & Coupland, C. A. (2023). Risk prediction of covid-19 related death or hospital admission in adults testing positive for SARS-CoV-2 infection during the omicron wave in England (QCOVID4): cohort study. British Medical Journal, 381, Article e072976. https://doi.org/10.1136/bmj-2022-072976

Objectives To derive and validate risk prediction algorithms (QCOVID4) to estimate the risk of covid-19 related death and hospital admission in people with a positive SARS-CoV-2 test result during the period when the omicron variant of the virus was... Read More about Risk prediction of covid-19 related death or hospital admission in adults testing positive for SARS-CoV-2 infection during the omicron wave in England (QCOVID4): cohort study.

Reactogenicity, immunogenicity and breakthrough infections following heterologous or fractional second dose COVID-19 vaccination in adolescents (Com-COV3): A randomised controlled trial (2023)
Journal Article
Kelly, E., Greenland, M., de Whalley, P. C., Aley, P. K., Plested, E. L., Singh, N., Koleva, S., Tonner, S., Macaulay, G. C., Read, R. C., Ramsay, M., Cameron, J. C., Turner, D. P., Heath, P. T., Bernatoniene, J., Connor, P., Cathie, K., Faust, S. N., Banerjee, I., Cantrell, L., …Com-COV3 Study Group, C.-C. S. G. (2023). Reactogenicity, immunogenicity and breakthrough infections following heterologous or fractional second dose COVID-19 vaccination in adolescents (Com-COV3): A randomised controlled trial. Journal of Infection, 87(3), 230-241. https://doi.org/10.1016/j.jinf.2023.06.007

Background: This was the first study to investigate the reactogenicity and immunogenicity of heterologous or fractional second dose COVID-19 vaccine regimens in adolescents. Methods: A phase II, single-blind, multi-centre, randomised-controlled trial... Read More about Reactogenicity, immunogenicity and breakthrough infections following heterologous or fractional second dose COVID-19 vaccination in adolescents (Com-COV3): A randomised controlled trial.

Hydrothermal synthesis of zeolites using silica extracted from tropical volcanic ash (2023)
Journal Article
Otieno, S. O., Kengara, F. O., Kowenje, C. O., & Mokaya, R. (2023). Hydrothermal synthesis of zeolites using silica extracted from tropical volcanic ash. Materials Advances, 4(10), 2292-2300. https://doi.org/10.1039/d3ma00065f

This study addresses the reliance on costly aluminosilicate sources for the synthesis of zeolites by exploring the use of silica extracted from tropical volcanic ash. The volcanic ash contained CaO, in the form of calcite polymorph of CaCO3, and sili... Read More about Hydrothermal synthesis of zeolites using silica extracted from tropical volcanic ash.

Changing water quality and thermocline depth along an aquaculture gradient in six tropical crater lakes (2022)
Journal Article
Briddon, C. L., Metcalfe, S., Taylor, D., Bannister, W., Cunanan, M., Santos-Borja, A. C., Papa, R. D., & McGowan, S. (2023). Changing water quality and thermocline depth along an aquaculture gradient in six tropical crater lakes. Hydrobiologia, 850(2), 283-299. https://doi.org/10.1007/s10750-022-05065-7

Understanding how lakes respond to changes in nutrient loading along a productivity gradient can help identify key drivers of aquatic change, thereby allowing appropriate mitigation strategies to be developed. Physical, chemical and biological water... Read More about Changing water quality and thermocline depth along an aquaculture gradient in six tropical crater lakes.