Outputs (7)

Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors (2025)
Journal Article
Sabri, A. H., Smith, F., Cater, Z., Gurnani, P., Nash, A., Brentville, V., Durrant, L., McKenna, J., Segal, J., Scurr, D. J., & Marlow, M. (2025). Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors. Drug Delivery, 32(1), Article 2527824. https://doi.org/10.1080/10717544.2025.2527824

Topical therapy with imiquimod in a cream [5% w/w imiquimod cream (Aldara™)] for the treatment of nodular basal cell carcinoma (BCC) currently results in low cure rates, attributed to low imiquimod permeation. Herein we have developed novel microneed... Read More about Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors.

Polyglycerol Resin Towards Sustainable 3D-Printing (2025)
Journal Article
George, K., Krumins, E., Tan, E., He, Y., Wildman, R. D., Owen, R., Segal, J., Cuzzucoli Crucitti, V., & Taresco, V. (2025). Polyglycerol Resin Towards Sustainable 3D-Printing. Faraday Discussions, https://doi.org/10.1039/d5fd00043b

Additive manufacturing (AM) techniques, also named as three-dimensional 3D-printing, have been widely recognised as promising technologies for rapid production of novel, personalised drug-delivery systems, scaffolds for biofabrication, food applicati... Read More about Polyglycerol Resin Towards Sustainable 3D-Printing.

A design of experiments (DoE) approach to identify the influencing parameters that determine poly-D,L-lactic acid (PDLLA) electrospun scaffold morphologies (2017)
Journal Article
Ruiter, F. A. A., Alexander, C., Rose, F. R., & Segal, J. (2017). A design of experiments (DoE) approach to identify the influencing parameters that determine poly-D,L-lactic acid (PDLLA) electrospun scaffold morphologies. Biomedical Materials, 12(5), Article 055009. https://doi.org/10.1088/1748-605X/aa7b54

Electrospun fibrous materials have increasing applications in regenerative medicine due to the similarity of fibre constructs to the morphology of certain extracellular matrices. Although experimentally the electrospinning method is relatively simple... Read More about A design of experiments (DoE) approach to identify the influencing parameters that determine poly-D,L-lactic acid (PDLLA) electrospun scaffold morphologies.

Cyclic pressure on compression-moulded bioresorbable phosphate glass fibre reinforced composites (2016)
Journal Article
Barrera Betanzos, F., Gimeno-Fabra, M., Segal, J., Grant, D., & Ahmed, I. (2016). Cyclic pressure on compression-moulded bioresorbable phosphate glass fibre reinforced composites. Materials and Design, 100, https://doi.org/10.1016/j.matdes.2016.03.108

The use of thermoplastic composites based on poly(lactic) acid and phosphate glass fibres over metallic alloys for clinical restorative treatment is highly beneficial due to their biocompatibility and biodegradability. However, difficulties in achiev... Read More about Cyclic pressure on compression-moulded bioresorbable phosphate glass fibre reinforced composites.

Degradation and Characterization of Resorbable Phosphate-Based Glass Thin-Film Coatings Applied by Radio-Frequency Magnetron Sputtering (2015)
Journal Article
Stuart, B. W., Stuart, B., Gimeno-Fabra, M., Segal, J., Ahmed, I., & Grant, D. M. (2015). Degradation and Characterization of Resorbable Phosphate-Based Glass Thin-Film Coatings Applied by Radio-Frequency Magnetron Sputtering. ACS Applied Materials and Interfaces, 7(49), 27362-27372. https://doi.org/10.1021/acsami.5b08957

Quinternary phosphate-based glasses of up to 2.67 μm, deposited by radio-frequency magnetron sputtering, were degraded in distilled water and phosphate-buffered saline (PBS) to investigate their degradation characteristics. Magnetron- sputtered coati... Read More about Degradation and Characterization of Resorbable Phosphate-Based Glass Thin-Film Coatings Applied by Radio-Frequency Magnetron Sputtering.

Apparent beam size definition of focused ion beams based on scanning electron microscopy images of nanodots (2015)
Journal Article
Vladov, N., Segal, J., & Ratchev, S. (2015). Apparent beam size definition of focused ion beams based on scanning electron microscopy images of nanodots. Journal of Vacuum Science and Technology B Microelectronics and Nanometer Structures, 33, Article 041803. https://doi.org/10.1116/1.4926388

In this paper the new term apparent beam size of Focused Ion Beam (FIB) is introduced and an original method of its evaluation is demonstrated. Traditional methods of measuring the beam size, like the knife edge method, provide information about the... Read More about Apparent beam size definition of focused ion beams based on scanning electron microscopy images of nanodots.

Focused ion beam milling of brass for microinjection mould fabrication
Presentation / Conference Contribution
Vladov, N., Ratchev, S., & Segal, J. Focused ion beam milling of brass for microinjection mould fabrication. Presented at International Conference on Micromanufacturing (ICOMM 2011)

In this paper focused ion beam (FIB) milling (sputtering) is demonstrated for the fabrication of brass microinjection moulding inserts which have been previously conventionally milled. It is found that FIB milling of the α phase of the material resul... Read More about Focused ion beam milling of brass for microinjection mould fabrication.