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Outputs (6)

Is routine laboratory testing in healthy young patients taking isotretinoin necessary – a critically appraised topic (2022)
Journal Article
Affleck, A., Jackson, D., Williams, H. C., Chavez, P., & Albrecht, J. (2022). Is routine laboratory testing in healthy young patients taking isotretinoin necessary – a critically appraised topic. British Journal of Dermatology, 187(6), 857-865. https://doi.org/10.1111/bjd.21840

Clinical question: Is monitoring of liver function, lipids and full blood count necessary in healthy people taking isotretinoin?

Background: Routine blood testing was recommended in the original licence for Roaccutane™ (isotretinoin) in 1983. In r... Read More about Is routine laboratory testing in healthy young patients taking isotretinoin necessary – a critically appraised topic.

Interventions for basal cell carcinoma of the skin (2020)
Journal Article
Thomson, J., Hogan, S., Leonardi-Bee, J., Williams, H. C., & Bath-Hextall, F. J. (2020). Interventions for basal cell carcinoma of the skin. Cochrane Library, 2020, Article CD003412. https://doi.org/10.1002/14651858.CD003412.pub3

Background: Basal cell carcinoma (BCC) is the commonest cancer affecting white-skinned individuals, and worldwide incidence is increasing. Although rarely fatal, BCC is associated with significant morbidity and costs. First-line treatment is usually... Read More about Interventions for basal cell carcinoma of the skin.

Personalised prediction of daily eczema severity scores using a mechanistic machine learning model (2020)
Journal Article
Hurault, G., Domínguez‐Hüttinger, E., Langan, S. M., Williams, H. C., & Tanaka, R. J. (2020). Personalised prediction of daily eczema severity scores using a mechanistic machine learning model. Clinical and Experimental Allergy, 50(11), 1258-1266. https://doi.org/10.1111/cea.13717

Background

Atopic dermatitis (AD) is a chronic inflammatory skin disease with periods of flares and remission. Designing personalised treatment strategies for AD is challenging, given the apparent unpredictability and large variation in AD symptom... Read More about Personalised prediction of daily eczema severity scores using a mechanistic machine learning model.

A behaviour change package to prevent hand dermatitis in nurses working in health care: the SCIN cluster RCT (2019)
Journal Article
Madan, I., Parsons, V., Ntani, G., Wright, A., English, J., Coggon, D., McCrone, P., Smedley, J., Rushton, L., Murphy, C., Cookson, B., Lavender, T., & Williams, H. (2019). A behaviour change package to prevent hand dermatitis in nurses working in health care: the SCIN cluster RCT. Health Technology Assessment, 23(58), 1-92. https://doi.org/10.3310/hta23580

BACKGROUND: Although strategies have been developed to minimise the risk of occupational hand dermatitis in nurses, their clinical effectiveness and cost-effectiveness remain unclear. OBJECTIVES: The Skin Care Intervention in Nurses trial tested the... Read More about A behaviour change package to prevent hand dermatitis in nurses working in health care: the SCIN cluster RCT.

Interventions to reduce Staphylococcus aureus in the management of eczema (2019)
Journal Article
George, S. M., Karanovic, S., Harrison, D. A., Rani, A., Birnie, A. J., Bath-Hextall, F. J., Ravenscroft, J. C., & Williams, H. C. (2019). Interventions to reduce Staphylococcus aureus in the management of eczema. Cochrane Database of Systematic Reviews, 2019(10), 145. https://doi.org/10.1002/14651858.cd003871.pub3

© 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background Staphylococcus aureus (S. aureus) can cause secondary infection in eczema, and may promote inflammation in eczema that does not look infected. There is no standard i... Read More about Interventions to reduce Staphylococcus aureus in the management of eczema.