Professor MARK VAN ROSSUM's Outputs (2)

Fluctuations in the open time of synaptic channels: an application to noise analysis based on charge (2011)
Journal Article
Feldwisch-Drentrup, H., Barrett, A. B., Smith, M. T., & van Rossum, M. C. (2012). Fluctuations in the open time of synaptic channels: an application to noise analysis based on charge. Journal of Neuroscience Methods, 210(1), https://doi.org/10.1016/j.jneumeth.2011.11.004

Synaptic channels are stochastic devices. Even recording from large ensembles of channels, the fluctuations, described by Markov transition matrices, can be used to extract single channel properties. Here we study fluctuations in the open time of cha... Read More about Fluctuations in the open time of synaptic channels: an application to noise analysis based on charge.

Dendritic spine dynamics regulate the long-term stability of synaptic plasticity (2011)
Journal Article
O'Donnell, C., Nolan, M. F., & van Rossum, M. C. (2011). Dendritic spine dynamics regulate the long-term stability of synaptic plasticity. Journal of Neuroscience, 31(45), https://doi.org/10.1523/JNEUROSCI.2520-11.2011

Long-term synaptic plasticity requires postsynaptic influx of Ca²⁺ and is accompanied by changes in dendritic spine size. Unless Ca²⁺ influx mechanisms and spine volume scale proportionally, changes in spine size will modify spine Ca²⁺ concentrations... Read More about Dendritic spine dynamics regulate the long-term stability of synaptic plasticity.