Skip to main content

Research Repository

Advanced Search

Dr Ruth Griffin's Outputs (3)

Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages (2006)
Journal Article
Rosas-Magallanes, V., Stadthagen-Gomez, G., Rauzier, J., Barreiro, L. B., Tailleux, L., Boudou, F., Griffin, R., Nigou, J., Jackson, M., Gicquel, B., & Neyrolles, O. (2007). Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages. Infection and Immunity, 75(1), 504-507. https://doi.org/10.1128/IAI.00058-06

Using signature-tagged transposon mutagenesis, we isolated 23 Mycobacterium tuberculosis mutants, corresponding to 21 genes or genetic regions, attenuated in their ability to parasitize human macrophages. Mutants disrupted in the ABC transporter-enco... Read More about Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages.

The future of tuberculosis vaccinology (2006)
Book Chapter
Griffin, R., & Young, D. (2006). The future of tuberculosis vaccinology. In M. C. Raviglione (Ed.), Reichman and Hershfield's tuberculosis : a comprehensive, international approach (1153-1168). (3rd ed.). Informa Healthcare

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives (2006)
Journal Article
Stadthagen, G., Jackson, M., Charles, P., Boudoua, F., Barilonea, N., Huerree, M., Constant, P., Liav, A., Bottova, I., Nigou, J., Brandod, T., Puzo, G., Daffé, M., Benjamin, P., Coade, S., Buxton, R. S., Tascon, R. E., Rae, A., Robertson, B. D., Lowrie, D. B., …Griffin, R. (in press). Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives. Microbes and Infection, 8(8), https://doi.org/10.1016/j.micinf.2006.04.008

p-Hydroxybenzoic acid derivatives (p-HBADs) are glycoconjugates secreted by all Mycobacterium tuberculosis isolates whose contribution to pathogenicity remains to be determined. The pathogenicity of three transposon mutants of M. tuberculosis deficie... Read More about Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives.