Molecular insights into an ancient form of Paget's disease of bone
(2019)
Journal Article
Shaw, B., Burrell, C. L., Green, D., Navarro-Martinez, A., Scott, D., Daroszewska, A., van't Hof, R., Smith, L., Hargrave, F., Mistry, S., Bottrill, A., Kessler, B., Fisher, R., Singh, A., Dalmay, T., Fraser, W. D., Henneberger, K., King, T., Gonzalez, S., & Layfield, R. (2019). Molecular insights into an ancient form of Paget's disease of bone. Proceedings of the National Academy of Sciences, 116(21), 10463-10472. https://doi.org/10.1073/pnas.1820556116
We identify an ancient and atypical form of Paget’s disease of bone (PDB) in a collection of medieval skeletons exhibiting unusually extensive pathological changes, high disease prevalence, and low age-at-death estimations. Proteomic analysis of anci... Read More about Molecular insights into an ancient form of Paget's disease of bone.