Characterisation of dysplastic liver nodules using low-pass DNA sequencing and detection of chromosome arm-level abnormalities in blood-derived cell-free DNA
(2021)
Journal Article
Fateen, W., Johnson, P. J., Wood, H. M., Zhang, H., He, S., El-Meteini, M., Wyatt, J. I., Aithal, G. P., & Quirke, P. (2021). Characterisation of dysplastic liver nodules using low-pass DNA sequencing and detection of chromosome arm-level abnormalities in blood-derived cell-free DNA. Journal of Pathology, 255(1), 30-40. https://doi.org/10.1002/path.5734
High grade dysplasia carries significant risk of transformation to hepatocellular carcinoma (HCC). Despite this, at the current standard of care, all non-malignant hepatic nodules including high grade dysplastic nodules are managed similarly. This is... Read More about Characterisation of dysplastic liver nodules using low-pass DNA sequencing and detection of chromosome arm-level abnormalities in blood-derived cell-free DNA.