The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor
(2016)
Presentation / Conference Contribution
Mistry, S. N., & Baker, J. G. The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor. Presented at British Pharmacological Society - 6th Focused Meeting on Cell Signalling, Spring 2016
Dr SHAILESH MISTRY's Outputs (4)
The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor (2016)
Presentation / Conference Contribution
Mistry, S. N., & Baker, J. G. The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor. Presented at British Pharmacological Society 6th Focused Meeting on Cell Signalling 2016
Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists (2013)
Journal Article
Mistry, S. N., Baker, J. G., Fischer, P. M., Hill, S. J., Gardiner, S. M., & Kellam, B. (2013). Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists. Journal of Medicinal Chemistry, 56(10), https://doi.org/10.1021/jm400348gβ-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β1-... Read More about Synthesis and in vitro and in vivo characterization of highly β1-Selective β-Adrenoceptor partial agonists.
In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist. (2012)
Presentation / Conference Contribution
Baker, J. G., Mistry, S. N., Fischer, P. M., Hill, S. J., Gardiner, S. M., & Kellam, B. In vitro and in vivo analysis of a novel highly selective β1-adrenoceptor partial agonist. Presented at British Pharmacological Society 4th Focused Meeting on Cell Signalling