Dr JON HOBMAN's Outputs (5)

Draft genome sequences of 14 Escherichia coli phages isolated from cattle slurry (2015)
Journal Article
Smith, R., O'Hara, M., Hobman, J. L., & Millard, A. (2015). Draft genome sequences of 14 Escherichia coli phages isolated from cattle slurry. Genome Announcements, 3(6), Article e01364-15. https://doi.org/10.1128/genomeA.01364-15

The diversity of bacteriophages in slurry from dairy cows remains largely unknown. Here, we report the draft genome sequences of 14 bacteriophages isolated from dairy cow slurry using Escherichia coli K-12 MG1655 as a host.

Survival in amoeba: a major selection pressure on the presence of bacterial copper and zinc resistance determinants?: identification of a "copper pathogenicity island" (2015)
Journal Article
Hao, X., Luthje, F. L., Qin, Y., McDevitt, S. F., Lutay, N., Hobman, J. L., Asiani, K., Soncini, F. C., German, N., Zhang, S., Zhu, Y.-G., & Rensing, C. (2015). Survival in amoeba: a major selection pressure on the presence of bacterial copper and zinc resistance determinants?: identification of a "copper pathogenicity island". Applied Microbiology and Biotechnology, 99(14), https://doi.org/10.1007/s00253-015-6749-0

The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. Whi... Read More about Survival in amoeba: a major selection pressure on the presence of bacterial copper and zinc resistance determinants?: identification of a "copper pathogenicity island".

Bacterial antimicrobial metal ion resistance (2015)
Journal Article
Hobman, J. L., & Crossman, L. (2015). Bacterial antimicrobial metal ion resistance. Journal of Medical Microbiology, 64, https://doi.org/10.1099/jmm.0.023036-0

Metals such as mercury, arsenic, copper and silver have been used in various forms as antimicrobials for thousands of years with until recently, little understanding of their mode of action. The discovery of antibiotics and new organic antimicrobial... Read More about Bacterial antimicrobial metal ion resistance.

The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress (2015)
Journal Article
Takahashi, H., Oshima, T., Hobman, J. L., Doherty, N., Clayton, S. R., Iqbal, M., Hill, P. J., Tobe, T., Ogasawara, N., Kanaya, S., & Stekel, D. J. (2015). The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress. Interface, 12(106), Article 20150069. https://doi.org/10.1098/rsif.2015.0069

Zinc is essential for life, but toxic in excess. Thus all cells must control their internal zinc concentration. We used a systems approach, alternating rounds of experiments and models, to further elucidate the zinc control systems in Escherichia col... Read More about The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress.

Response of Cupriavidus metallidurans CH34 to metals (2015)
Book Chapter
Monsieurs, P., Hobman, J. L., Vandenbussche, G., Mergeay, M., & Van Hoult, R. (2015). Response of Cupriavidus metallidurans CH34 to metals. In M. Mergay, & R. Van Houdt (Eds.), Metal response in Cupriavidus metallidurans Volume 1: From habitats to genes and proteins. Springer. https://doi.org/10.1007/978-3-319-20594-6

Cupriavidus metallidurans CH34 displays resistance to a plethora of metals. Its response and underlying genetic determinants are dissected and detailed metal by metal (from arsenic to zinc). An important role for its megaplasmids pMOL28 and pMOL30 is... Read More about Response of Cupriavidus metallidurans CH34 to metals.