Professor SIMON PRESTON's Outputs (2)

Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution (2013)
Journal Article
White, S. R., Kypraios, T., & Preston, S. P. (2015). Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution. Statistics and Computing, 25(2), 289-301. https://doi.org/10.1007/s11222-013-9432-2

© 2013, The Author(s). Many modern statistical applications involve inference for complicated stochastic models for which the likelihood function is difficult or even impossible to calculate, and hence conventional likelihood-based inferential techni... Read More about Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution.

Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs (2013)
Journal Article
Hirt, B. V., Wattis, J. A., & Preston, S. P. (2014). Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs. Journal of Mathematical Biology, 68(6), 1521-1552. https://doi.org/10.1007/s00285-013-0678-2

Telomeres are guanine-rich sequences at the end of chromosomes which shorten during each replication event and trigger cell cycle arrest and/or controlled death (apoptosis) when reaching a threshold length. The enzyme telomerase replenishes the ends... Read More about Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs.