Professor Roshan Nair's Outputs (158)

Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial (2023)
Preprint / Working Paper
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., Hoare, Z., Hancox, J., Bajwa, R., Burgon, C., Howe, L., Cowley, A., Bramley, T., Long, A., Lock, J., Tucker, R., Adams, E., O’Brien, R., Kearney, F., Kowalewska, K., …Masud, T. Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial

Background Dementia is associated with frailty leading to increased risks of falls and hospitalisations. Interventions are required to maintain functional ability, strength and balance.

Design Multi-centre parallel group randomised controlled tria... Read More about Promoting Activity, Independence and Stability in early dementia and mild cognitive impairment (PrAISED): A randomised controlled trial.

The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia (2022)
Preprint / Working Paper
Di Lorito, C., van der Wardt, V., Pollock, K., Howe, L., Booth, V., Logan, P., Gladman, J., Masud, T., das Nair, R., Goldberg, S., vedhara, K., O'Brien, R., Adams, E., Cowley, A., Bosco, A., Hancox, J., Burgon, C., Bajwa, R., Lock, J., Long, A., …Harwood, R. (2022). The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia

Background The PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise and functional activity programme to participants living with dementia. A Randomised Controlled Trial (RCT) showed no measurable ben... Read More about The facilitators and barriers to improving functional activity and wellbeing in people with dementia: A qualitative study from the Process Evaluation of Promoting Activity, Independence and Stability in Early Dementia.

Reflections on RRI in “TAS for Health at Home” (2022)
Journal Article
Jäger, N., Dowthwaite, L., Barnard, P., Hughes, A.-M., das Nair, R., Crepaz-Keay, D., Cobb, S., Lang, A., Vayani, F., & Benford, S. (2022). Reflections on RRI in “TAS for Health at Home”. Journal of Responsible Technology, 12, Article 100049. https://doi.org/10.1016/j.jrt.2022.100049

We reflect on our experiences using Responsible Research and Innovation (RRI) in the project “TAS for Health at Home”. Driven by a multi-disciplinary research team that consisted of experts in mental health, stroke rehabilitation, management of multi... Read More about Reflections on RRI in “TAS for Health at Home”.

Decentralised clinical trials in multiple sclerosis research (2022)
Journal Article
Garjani, A., Liu, B. J.-Y., Allen, C. M., Gunzler, D. D., Gerry, S. W., Planchon, S. M., das Nair, R., Chataway, J., Tallantyre, E. C., Ontaneda, D., & Evangelou, N. (2023). Decentralised clinical trials in multiple sclerosis research. Multiple Sclerosis Journal, 29(3), 317-325. https://doi.org/10.1177/13524585221100401

Randomised controlled trials (RCTs) play an important role in multiple sclerosis (MS) research, ensuring that new interventions are safe and efficacious before their introduction into clinical practice. Trials have been evolving to improve the robust... Read More about Decentralised clinical trials in multiple sclerosis research.

Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial (2022)
Journal Article
Topcu, G., Smith, L., Mhizha-Murira, J. R., Goulden, N., Hoare, Z., Drummond, A., Fitzsimmons, D., Evangelou, N., Schmierer, K., Tallantyre, E. C., Leighton, P., Allen-Philbey, K., Stennett, A., Bradley, P., Bale, C., Turton, J., das Nair, R., & On behalf of the NEuRoMS Collective. (2022). Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial. Pilot and Feasibility Studies, 8(1), Article 123. https://doi.org/10.1186/s40814-022-01073-5

Background: Cognitive problems affect up to 70% of people with multiple sclerosis (MS), which can negatively impact mood, ability to work, and quality of life. Addressing cognitive problems is a top 10 research priority for people with MS. Our ongoin... Read More about Neuropsychological evaluation and rehabilitation in multiple sclerosis (NEuRoMS): protocol for a mixed-methods, multicentre feasibility randomised controlled trial.

Experiences of people with multiple sclerosis at work: Towards the understanding of the needs for a job retention vocational rehabilitation intervention (2022)
Journal Article
De dios perez, B., Radford, K., & das Nair, R. (2022). Experiences of people with multiple sclerosis at work: Towards the understanding of the needs for a job retention vocational rehabilitation intervention. WORK: A Journal of Prevention, Assessment & Rehabilitation, 72(1), 303-313. https://doi.org/10.3233/wor-210012

Background: Supporting people with multiple sclerosis (MS) at work can be challenging due to the unpredictable nature and myriad of disease-related symptoms, and issues related to the work environment.

Objective: To explore, amongst people with MS... Read More about Experiences of people with multiple sclerosis at work: Towards the understanding of the needs for a job retention vocational rehabilitation intervention.

Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis (2022)
Journal Article
Thompson, B., Moghaddam, N., Evangelou, N., Baufeldt, A., & das Nair, R. (2022). Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders, 63, Article 103862. https://doi.org/10.1016/j.msard.2022.103862

Objective: To review the evidence for the effectiveness of Acceptance and Commitment Therapy (ACT) intervention on quality of life and mood, for individuals with Multiple Sclerosis (MS). Method: A systematic search was conducted of PsycINFO, CINAHL,... Read More about Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis.

UK clinical approaches to address post-stroke fatigue: findings from The Nottingham Fatigue after Stroke study (2022)
Journal Article
Ablewhite, J., Condon, L., das Nair, R., Jones, A., Jones, F., Nouri, F., Sprigg, N., Thomas, S., & Drummond, A. (2022). UK clinical approaches to address post-stroke fatigue: findings from The Nottingham Fatigue after Stroke study. International Journal of Therapy and Rehabilitation, 29(5), 1-12. https://doi.org/10.12968/ijtr.2021.0163

Background/aims Although post-stroke is common and debilitating, there is little published research on how it is managed by clinicians. The aim of this study was to document UK management of post-stroke fatigue and ascertain whether there are any dif... Read More about UK clinical approaches to address post-stroke fatigue: findings from The Nottingham Fatigue after Stroke study.

Relaxation and related therapies for people with multiple sclerosis (MS): A systematic review (2022)
Journal Article
Kneebone, I., Van Zanden, B., Dorstyn, D., Roberts, R., Lord, S., Querstret, D., Theadom, A., Kennedy, D., Raman, J., & Nair, R. D. (2022). Relaxation and related therapies for people with multiple sclerosis (MS): A systematic review. Clinical Rehabilitation, 36(7), 883-899. https://doi.org/10.1177/02692155221091509

Objective: To establish the effectiveness of relaxation and related therapies in treating Multiple Sclerosis related symptoms and sequelae. Data Sources: PsycINFO, PubMed, Embase, CINAHL, ProQuest Dissertations and Theses Global databases were search... Read More about Relaxation and related therapies for people with multiple sclerosis (MS): A systematic review.

Qualitative study exploring factors affecting the implementation of a vocational rehabilitation intervention in the UK major trauma pathway (2022)
Journal Article
Kettlewell, J., Radford, K., Kendrick, D., Patel, P., Bridger, K., Kellezi, B., Das Nair, R., Jones, T., & Timmons, S. (2022). Qualitative study exploring factors affecting the implementation of a vocational rehabilitation intervention in the UK major trauma pathway. BMJ Open, 12(3), Article e060294. https://doi.org/10.1136/bmjopen-2021-060294

Objectives This study aimed to: (1) understand the context for delivering a trauma vocational rehabilitation (VR) intervention; (2) identify potential barriers and enablers to the implementation of a VR intervention post-trauma. Design Qualitative st... Read More about Qualitative study exploring factors affecting the implementation of a vocational rehabilitation intervention in the UK major trauma pathway.

Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial (2022)
Journal Article
Hancox, J., Ayling, K., Bedford, L., Vedhara, K., Robertson, J. F. R., Young, B., das Nair, R., Sullivan, F. M., Schembri, S., Mair, F. S., Littleford, R., & Kendrick., D. (2023). Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial. Journal of Public Health, 45(2), e275–e284. https://doi.org/10.1093/pubmed/fdac032

Background: The Early CDT®-Lung antibody blood test plus serial CT-scans for test-positives reduces late-stage lung cancer presentation. This study assessed psychological outcomes of this approach.

Methods: Randomised controlled trial (n=12,208) c... Read More about Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomised controlled trial.

Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies (2022)
Journal Article
Topcu, G., Mhizha-Murira, J. R., Griffiths, H., Bale, C., Drummond, A., Fitzsimmons, D., Potter, K. J., Evangelou, N., & das Nair, R. (2023). Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies. Disability and Rehabilitation, 45(5), 772-783. https://doi.org/10.1080/09638288.2022.2046187

Purpose: This meta-synthesis aimed to synthesise qualitative evidence on experiences of people with Multiple Sclerosis (MS) in receiving a diagnosis, to derive a conceptual understanding of adjustment to MS diagnosis. Methods: Five electronic databas... Read More about Experiences of receiving a diagnosis of multiple sclerosis: a meta-synthesis of qualitative studies.

Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences (2022)
Journal Article
Nomikos, P. A., Hall, M. C., Fuller, A., Ogollah, R., Valdes, A. M., Doherty, M., Walsh, D. A., das Nair, R., & Abhishek, A. (2022). Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences. PLoS ONE, 17(1), Article e0262422. https://doi.org/10.1371/journal.pone.0262422

Objectives The overall purpose of this research programme is to develop and test the feasibility of a complex intervention for knee pain delivered by a nurse, and comprising both non-pharmacological and pharmacological interventions. In this first ph... Read More about Acceptability of a nurse-led non-pharmacological complex intervention for knee pain: Nurse and patient views and experiences.

Memory rehabilitation for people with multiple sclerosis (2021)
Journal Article
Taylor, L. A., Mhizha-Murira, J. R., Smith, L., Potter, K.-J., Wong, D., Evangelou, N., Lincoln, N. B., & das Nair, R. (2021). Memory rehabilitation for people with multiple sclerosis. Cochrane Library, 2021(10), Article CD008754. https://doi.org/10.1002/14651858.cd008754.pub4

Background
Problems with cognition, particularly memory, are common in people with multiple sclerosis (MS) and can affect their ability to complete daily activities and can negatively affect quality of life. Over the last few years, there has been c... Read More about Memory rehabilitation for people with multiple sclerosis.

COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register (2021)
Journal Article
Middleton, R. M., Craig, E. M., Rodgers, W. J., Tuite-Dalton, K., Garjani, A., Evangelou, N., das Nair, R., Hunter, R., Tallantyre, E. C., Cauchi, M., Cairn, C., Paling, D., Fuller, S., McDonnell, G., Petherham, K., Liu, B., Nock, U., Ingram, G., Brownlee, W., Taylor, J., …UK Multiple Sclerosis Register Research Group. (2021). COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register. Multiple Sclerosis and Related Disorders, 56, Article 103317. https://doi.org/10.1016/j.msard.2021.103317

Background: In March 2020, the United Kingdom Multiple Sclerosis Register (UKMSR) established an electronic case return form, designed collaboratively by MS neurologists, to record data about COVID-19 infections in people with MS (pwMS). Objectives:... Read More about COVID-19 in Multiple Sclerosis: Clinically reported outcomes from the UK Multiple Sclerosis Register.

Improving smoking cessation support for people with multiple sclerosis: A qualitative analysis of clinicians’ views and current practice (2021)
Journal Article
Grech, L. B., Hunter, A., das Nair, R., Borland, R., & Marck, C. H. (2021). Improving smoking cessation support for people with multiple sclerosis: A qualitative analysis of clinicians’ views and current practice. Multiple Sclerosis and Related Disorders, 56, Article 103289. https://doi.org/10.1016/j.msard.2021.103289

Introduction Smoking is a key modifiable risk factor in multiple sclerosis (MS). MS healthcare providers have a central role informing people of the deleterious effects of smoking on MS progression and promote smoking cessation, yet there is limited... Read More about Improving smoking cessation support for people with multiple sclerosis: A qualitative analysis of clinicians’ views and current practice.

Managing post-stroke fatigue: A qualitative study to explore multifaceted clinical perspectives (2021)
Journal Article
Drummond, A., Nouri, F., Ablewhite, J., Condon, L., Das Nair, R., Jones, A., Jones, F., Sprigg, N., & Thomas, S. (2022). Managing post-stroke fatigue: A qualitative study to explore multifaceted clinical perspectives. British Journal of Occupational Therapy, 85(7), 505-512. https://doi.org/10.1177/03080226211042269

Introduction: Post-stroke fatigue (PSF) is common and debilitating. However, while its effective management is a priority for clinicians and stroke survivors, there remains little evidence to provide guidance or underpin practice. Our aim, therefore,... Read More about Managing post-stroke fatigue: A qualitative study to explore multifaceted clinical perspectives.

A single-case experimental evaluation of a new group-based intervention to enhance adjustment to life with acquired brain injury: VaLiANT (valued living after neurological trauma) (2021)
Journal Article
Sathananthan, N., Dimech-Betancourt, B., Morris, E., Vicendese, D., Knox, L., Gillanders, D., Das Nair, R., & Wong, D. (2022). A single-case experimental evaluation of a new group-based intervention to enhance adjustment to life with acquired brain injury: VaLiANT (valued living after neurological trauma). Neuropsychological Rehabilitation, 32(8), 2170-2202. https://doi.org/10.1080/09602011.2021.1971094

Adjustment to life with acquired brain injury (ABI) requires self-identity and behaviour to be updated, incorporating injury-related changes. Identifying and enabling new values-consistent behaviours could facilitate this process. We evaluated the fe... Read More about A single-case experimental evaluation of a new group-based intervention to enhance adjustment to life with acquired brain injury: VaLiANT (valued living after neurological trauma).

Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study (2021)
Journal Article
Nomikos, P. A., Hall, M., Fuller, A., Millar, B., Ogollah, R., Valdes, A., Doherty, M., Walsh, D. A., Das Nair, R., & Abhishek, A. (2021). Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study. BMJ Open, 11(7), Article e045242. https://doi.org/10.1136/bmjopen-2020-045242

Objectives To evaluate fidelity of delivery of a nurse-led non-pharmacological complex intervention for knee pain. Setting Secondary care. Single-centre study. Study design Mixed methods study. Participants Eighteen adults with chronic knee pain. Inc... Read More about Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: A mixed methods study.

Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial (2021)
Journal Article
Meek, C., Moghaddam, N. G., Evangelou, N., Oates, L. L., Topcu, G., Allen, C., & das Nair, R. (2021). Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial. Journal of Contextual Behavioral Science, 21, 158-170. https://doi.org/10.1016/j.jcbs.2021.07.001

Introduction
Transitioning to secondary progressive multiple sclerosis (SPMS) is a difficult time for people, fraught with psychological uncertainty and an increase in physical disability. In parallel, healthcare appointments become less frequent, m... Read More about Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial.