Professor CLIVE ROBERTS's Outputs (2)

Cetuximab-conjugated chitosan-pectinate (modified) composite nanoparticles for targeting colon cancer (2019)
Journal Article
Sabra, R., Billa, N., & Roberts, C. J. (2019). Cetuximab-conjugated chitosan-pectinate (modified) composite nanoparticles for targeting colon cancer. International Journal of Pharmaceutics, 572, Article 118775. https://doi.org/10.1016/j.ijpharm.2019.118775

© 2019 Elsevier B.V. In the present study, we successfully developed a cetuximab-conjugated modified citrus pectin-chitosan nanoparticles for targeted delivery of curcumin (Cet-MCPCNPs) for the treatment of colorectal cancer. In vitro analyses reveal... Read More about Cetuximab-conjugated chitosan-pectinate (modified) composite nanoparticles for targeting colon cancer.

Nanofibrous scaffolds support a 3D in vitro permeability model of the human intestinal epitheleum (2019)
Journal Article
Patient, J. D., Hajiali, H., Harris, K., Abrahamsson, B., Tannergreen, C., White, L. J., Ghaemmaghami, A. M., Williams, P. M., Roberts, C. J., & Rose, F. R. (2019). Nanofibrous scaffolds support a 3D in vitro permeability model of the human intestinal epitheleum. Frontiers in Pharmacology, 10, Article 456. https://doi.org/10.3389/fphar.2019.00456

Advances in drug research not only depend on high throughput screening to evaluate large numbers of lead compounds but also on the development of in vitro models which can simulate human tissues in terms of drug permeability and functions. Potential... Read More about Nanofibrous scaffolds support a 3D in vitro permeability model of the human intestinal epitheleum.