Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study

Kendrick, Denise; Baker, Ruth; Hill, Trevor; Beckett, Kate; Coupland, Carol; Kellezi, Blerina; Joseph, Stephen; Barnes, Jo; Sleney, Judith; Christie, Nicola; Morriss, Richard

Abstract

Objective: To quantify psychological morbidity and identify baseline factors associated with depression, anxiety and post-traumatic distress symptoms up to 12 months post-injury.

Methods: Multicentre cohort study of 668 adults, aged 16 to 70, admitted to 4 UK NHS hospital trusts. Data on injury, socio-demographic characteristics and health status was collected at recruitment. Depression, anxiety and post-traumatic distress were measured at 1, 2, 4 and 12 months post-injury. Multilevel linear regression assessed associations between patient and injury characteristics and psychological outcomes over 12 months follow-up.

Results: Depression, anxiety and post-traumatic distress scores were highest 1 month post-injury, and remained above baseline at 2, 4 and 12 months post-injury.

Moderate or severe injuries, previous psychiatric diagnoses, higher pre-injury depression and anxiety scores, middle age (45-64 years), greater deprivation and lower pre-injury quality of life (QoL) were associated with higher depression scores post-injury.

Previous psychiatric diagnoses, higher pre-injury depression and anxiety scores, middle age, greater deprivation and lower pre-injury QoL were associated with higher anxiety scores post-injury.

Traffic injuries or injuries from being struck by objects, multiple injures (≥ 3), being female, previous psychiatric diagnoses, higher pre-injury anxiety scores and greater deprivation were associated with higher post-traumatic distress scores post-injury.

Conclusion: A range of risk factors, identifiable shortly after injury, are associated with psychological morbidity occurring up to 12 months post-injury in a general trauma population. Further research is required to explore the utility of these, and other risk factors in predicting psychological morbidity on an individual patient basis.

Citation

Kendrick, D., Baker, R., Hill, T., Beckett, K., Coupland, C., Kellezi, B., Joseph, S., Barnes, J., Sleney, J., Christie, N., & Morriss, R. (2018). Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study. Journal of Psychosomatic Research, 112, 15-24. https://doi.org/10.1016/j.jpsychores.2018.06.008

• Journal Article Type: Article
• Acceptance Date: Jun 11, 2018
• Online Publication Date: Jun 12, 2018
• Publication Date: Sep 30, 2018
• Deposit Date: Jun 20, 2018
• Publicly Available Date: Jun 13, 2019
• Journal: Journal of Psychosomatic Research
• Print ISSN: 0022-3999
• Electronic ISSN: 1879-1360
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 112
• Pages: 15-24
• DOI: https://doi.org/10.1016/j.jpsychores.2018.06.008
• Keywords: Depression; Anxiety; PTSD; Injury; Trauma
• Public URL: https://nottingham-repository.worktribe.com/output/950431
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S0022399917312254
• Related Public URLs: https://creativecommons.org/licenses/by-nc-nd/4.0/
• Contract Date: Jun 20, 2018