Gallium incorporation into phosphate based glasses: Bulk and thin film properties

Stuart, Bryan W.; Grant, Colin A.; Stan, George E.; Popa, Adrian C.; Titman, Jeremy J.; Grant, David M.

Abstract

The osteogenic ions Ca2+, P5+, Mg2+, and antimicrobial ion Ga3+ were homogenously dispersed into a 1.45 mum thick phosphate glass coating by plasma assisted sputtering onto CP grade titanium. The objective was to deliver therapeutic ions in orthopedic/dental implants such as hip prosthesis or dental screws. The hardness 4.7 GPa and elastic modulus 69.7 GPa, of the coating were comparable to plasma sprayed hydroxyapatite/dental enamel, whilst superseding femoral cortical bone. To investigate the manufacturing challenge of translation from a target to vapour condensed coating, structural/compositional properties of the target (P51MQ) were compared to the coating (P40PVD) and a melt-quenched equivalent (P40MQ). Following condensation from P51MQ to P40PVD, P2O5 content reduced from 48.9 to 40.5 mol%. This depolymerisation and reduction in the P-O-P bridging oxygen content as determined by 31P-NMR, FTIR and Raman spectroscopy techniques was attributed to a decrease in the P2O5 network former and increases in alkali/alkali-earth cations. P40PVD appeared denser (3.47 vs. 2.70 g cm-3) and more polymerised than it’s compositionally equivalent P40MQ, showing that structure/ mechanical properties were affected by manufacturing route.

Citation

Stuart, B. W., Grant, C. A., Stan, G. E., Popa, A. C., Titman, J. J., & Grant, D. M. (2018). Gallium incorporation into phosphate based glasses: Bulk and thin film properties. Journal of the Mechanical Behavior of Biomedical Materials, 82, 371-382. https://doi.org/10.1016/j.jmbbm.2018.03.041

• Journal Article Type: Article
• Acceptance Date: Mar 29, 2018
• Online Publication Date: Mar 30, 2018
• Publication Date: Jun 30, 2018
• Deposit Date: Jun 14, 2018
• Publicly Available Date: Mar 31, 2019
• Journal: Journal of the Mechanical Behavior of Biomedical Materials
• Print ISSN: 1751-6161
• Electronic ISSN: 1878-0180
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 82
• Pages: 371-382
• DOI: https://doi.org/10.1016/j.jmbbm.2018.03.041
• Keywords: Phosphate glass ; Sputtering ; Coating ; Osseointegration ; Antimicrobial
• Public URL: https://nottingham-repository.worktribe.com/output/944262
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S1751616118302856
• Contract Date: Jun 14, 2018