Increasing value and reducing waste in stroke research

Berge, Eivind; Al-Shahi Salman, Rustam; van der Worp, H. Bart; Stapf, Christian; Sandercock, Peter; Sprigg, Nikola; Macleod, Malcolm R.; Kelly, Peter J.; Nederkoorn, Paul J.; Ford, Gary A.

Abstract

Stroke represents a major burden to patients and society, and resources spent on stroke research must be used efficiently and produce good value in terms of improvements in human health. However, there are many examples of poor value from stroke research funding, which result from the way in which stroke research has been chosen, designed, conducted, analysed, regulated, managed, disseminated, or reported. In a project including a survey and a symposium and involving stroke researchers in the European Stroke Organisation we have sought to identify sources of inefficiency and waste, recommended approaches to increase value, and highlighted examples of best practice in stroke research. Recent evidence suggests that progress has been made, but there is room for much improvement, and stroke researchers, funders and other stakeholders might consider our recommendations when planning new research.

Citation

Berge, E., Al-Shahi Salman, R., van der Worp, H. B., Stapf, C., Sandercock, P., Sprigg, N., Macleod, M. R., Kelly, P. J., Nederkoorn, P. J., & Ford, G. A. (2017). Increasing value and reducing waste in stroke research. Lancet Neurology, 16(5), 399-408. https://doi.org/10.1016/S1474-4422%2817%2930078-9

• Journal Article Type: Article
• Acceptance Date: Feb 21, 2017
• Online Publication Date: Apr 11, 2017
• Publication Date: May 31, 2017
• Deposit Date: Sep 6, 2017
• Publicly Available Date: Sep 6, 2017
• Journal: Lancet Neurology
• Print ISSN: 1474-4422
• Electronic ISSN: 1474-4465
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 16
• Issue: 5
• Pages: 399-408
• DOI: https://doi.org/10.1016/S1474-4422%2817%2930078-9
• Keywords: Stroke research; prioritisation, design, conduct, analysis, regulation, management, accessibility, reporting, REWARD campaign
• Public URL: https://nottingham-repository.worktribe.com/output/863632
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S1474442217300789?via%3Dihub
• Additional Information: Authors on behalf of ESO Trials Network Committee.
• Contract Date: Sep 6, 2017