Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative

Leshem, Yael A.; Chalmers, Joanne R.; Apfelbacher, Christian; Furue, Masutaka; Gerbens, Louise A.A.; Prinsen, Cecilia A.C.; Schmitt, Jochen; Spuls, Phyllis I.; Thomas, Kim S.; Williams, Hywel C.; Simpson, Eric L.

Abstract

Background: Measuring patient-centered outcomes in clinical practice is valuable for monitoring patients and advancing real-world research. A new initiative from the Harmonising Outcome Measures for Eczema (HOME) group aims to recommend what might be recorded for atopic eczema patients in routine clinical care. Objectives: Prioritize outcome domains to measure atopic eczema in clinical practice and select valid and practical outcome measurement instruments for the highest-priority domain. Methods: An online survey of HOME members identified and ranked 21 possible health domains. Suitable instruments were then selected for the top-prioritized domain at the HOME VI meeting, using established consensus processes informed by systematic reviews of instrument quality. Results: Patient-reported symptoms was the top-prioritized domain. In accordance with psychometric properties and feasibility, there was consensus that the recommended instruments to measure atopic eczema symptoms in clinical practice are the POEM, the PO-SCORAD index, or both. The numeric rating scale for itch received support pending definition and validation in atopic eczema. Conclusion: Following the first step of the HOME Clinical Practice initiative, we endorse using the POEM, the PO-SCORAD index, or both for measuring atopic eczema symptoms in clinical practice. Additional high-priority domains for clinical practice will be assessed at subsequent HOME meetings.

Citation

Leshem, Y. A., Chalmers, J. R., Apfelbacher, C., Furue, M., Gerbens, L. A., Prinsen, C. A., Schmitt, J., Spuls, P. I., Thomas, K. S., Williams, H. C., & Simpson, E. L. (2020). Measuring atopic eczema symptoms in clinical practice: The first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice initiative. Journal of The American Academy of Dermatology, 82(5), 1181-1186. https://doi.org/10.1016/j.jaad.2019.12.055

• Journal Article Type: Article
• Acceptance Date: Dec 25, 2019
• Online Publication Date: Jan 8, 2020
• Publication Date: May 1, 2020
• Deposit Date: Feb 15, 2021
• Publicly Available Date: Feb 15, 2021
• Journal: Journal of the American Academy of Dermatology
• Print ISSN: 0190-9622
• Electronic ISSN: 1097-6787
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 82
• Issue: 5
• Pages: 1181-1186
• DOI: https://doi.org/10.1016/j.jaad.2019.12.055
• Keywords: Dermatology
• Public URL: https://nottingham-repository.worktribe.com/output/4982223
• Publisher URL: https://www.jaad.org/article/S0190-9622(20)30029-3/fulltext
• Additional Information: Authors on behalf of the Harmonising Outcome Measures for Eczema (HOME) initiative.