Geography, altitude, agriculture and hypoxia

Holdsworth, Michael J; Liu, Huanhuan; Castellana, Simone; Abbas, Mohamad; Liu, Jianquan; Perata, Pierdomenico

Abstract

Reduced oxygen availability (hypoxia) represents a key plant abiotic stress in natural and agricultural systems, but conversely it is also an important component of normal growth and development. We review recent advances that demonstrate how genetic adaptations associated with hypoxia impact the known plant oxygen sensing mechanism through the PLANT CYSTEINE OXIDASE (PCO) N-degron pathway. Only three protein substrates of this pathway have been identified, and all adaptations identified to date are associated with the most important of these, the group VII ETHYLENE RESPONSE FACTOR transcription factors (ERFVIIs). We discuss how geography, altitude, and agriculture have all shaped molecular responses to hypoxia, and how these responses have emerged at different taxonomic levels through the evolution of land plants. Understanding how ecological and agricultural genetic variation acts positively to enhance hypoxia tolerance will provide novel tools and concepts to improve the performance of crops in the face of increasing extreme flooding events.

Citation

Holdsworth, M. J., Liu, H., Castellana, S., Abbas, M., Liu, J., & Perata, P. (2025). Geography, altitude, agriculture and hypoxia. Plant Physiology, 197(1), Article kiae535. https://doi.org/10.1093/plphys/kiae535

• Journal Article Type: Article
• Acceptance Date: Oct 3, 2024
• Online Publication Date: Oct 4, 2024
• Publication Date: 2025-01
• Deposit Date: Nov 1, 2024
• Publicly Available Date: Nov 1, 2024
• Journal: Plant Physiology
• Print ISSN: 0032-0889
• Electronic ISSN: 1532-2548
• Publisher: American Society of Plant Biologists
• Peer Reviewed: Peer Reviewed
• Volume: 197
• Issue: 1
• Article Number: kiae535
• DOI: https://doi.org/10.1093/plphys/kiae535
• Public URL: https://nottingham-repository.worktribe.com/output/40295113
• Publisher URL: https://academic.oup.com/plphys/article/197/1/kiae535/7810944