Patient‐reported outcomes in studies of diabetes technology: What matters

Liarakos, Alexandros L.; Crabtree, Thomas S.J.; Wilmot, Emma G.

Abstract

In recent years, diabetes technologies have revolutionized the care of people with type1 diabetes (T1D). Emerging evidence suggests that people with type 2 diabetes (T2D) canexperience similar benefits from these advances in technology. While glycaemic outcomesare often a primary focus, the lived experience of the person with diabetes is equallyimportant. In this review, we describe the impact of diabetes technologies on patient-reported outcome measures (PROMs). We highlight that most of the published studiesinvestigated PROMs as secondary outcomes. Continuous glucose monitoring systems mayhave an important role in improving PROMs in individuals with T1D, which may be drivenby the prevention or proactive management of hypoglycaemia. In people with T2D, con-tinuous glucose monitoring may also have an important role in improving PROMs, particu-larly in those treated with insulin therapy. The impact of insulin pumps on PROMs seemspositive in T1D, while there is limited evidence in T2D. Studies of hybrid closed-loop ther-apies suggest increased treatment satisfaction, improved quality of life and decreaseddiabetes-related distress in T1D, but it is unclear whether these benefits are because of a‘class-effect’ or individual systems. We conclude that PROMs deserve a more central rolein trials and clinical practice, and we discuss directions for future research

Citation

Liarakos, A. L., Crabtree, T. S., & Wilmot, E. G. (2024). Patient‐reported outcomes in studies of diabetes technology: What matters. Diabetes, Obesity and Metabolism, 26(S7), 59-73. https://doi.org/10.1111/dom.15858

• Journal Article Type: Article
• Acceptance Date: Jul 20, 2024
• Online Publication Date: Dec 15, 2024
• Publication Date: 2024-12
• Deposit Date: Dec 31, 2024
• Publicly Available Date: Jan 7, 2025
• Journal: Diabetes, Obesity and Metabolism
• Print ISSN: 1462-8902
• Electronic ISSN: 1463-1326
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 26
• Issue: S7
• Pages: 59-73
• DOI: https://doi.org/10.1111/dom.15858
• Keywords: continuous glucose monitoring, continuous subcutaneous insulin infusion, insulin pump therapy,patient reported outcomes, type 1 diabetes, type 2 diabetes
• Public URL: https://nottingham-repository.worktribe.com/output/39176223
• Publisher URL: https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.15858