Hospital volume, proportion resected and mortality from oesophageal and gastric cancer: A population-based study in England, 2004-2008

Coupland, Victoria H.; Lagergren, Jesper; L�chtenborg, Margreet; Jack, Ruth H.; Allum, William; Holmberg, Lars; Hanna, George B.; Pearce, Neil; M�ller, Henrik

Abstract

Objective: This study assessed the associations between hospital volume, resection rate and survival of oesophageal and gastric cancer patients in England.

Design: 62 811 patients diagnosed with oesophageal or gastric cancer between 2004 and 2008 were identified from a national population-based cancer registration and Hospital Episode Statistics-linked dataset. Cox regression analyses were used to assess all-cause mortality according to hospital volume and resection rate, adjusting for case-mix variables (sex, age, socioeconomic deprivation, comorbidity and type of cancer). HRs and 95% CIs, according to hospital volume, were evaluated for three predefined periods following surgery: 365 days. Analysis of mortality in relation to resection rate was performed among all patients and among the 13 189 (21%) resected patients.

Results Increasing hospital volume was associated with lower mortality (ptrend=0.0001; HR 0.87, 95% CI 0.79 to 0.95 for hospitals resecting 80+ and compared with

Citation

Coupland, V. H., Lagergren, J., Lüchtenborg, M., Jack, R. H., Allum, W., Holmberg, L., …Møller, H. (2013). Hospital volume, proportion resected and mortality from oesophageal and gastric cancer: A population-based study in England, 2004-2008. Gut, 62(7), 961-966. https://doi.org/10.1136/gutjnl-2012-303008

• Journal Article Type: Article
• Acceptance Date: Sep 9, 2012
• Online Publication Date: Jun 6, 2013
• Publication Date: Jul 1, 2013
• Deposit Date: Apr 26, 2021
• Journal: Gut
• Print ISSN: 0017-5749
• Electronic ISSN: 1468-3288
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 62
• Issue: 7
• Pages: 961-966
• DOI: https://doi.org/10.1136/gutjnl-2012-303008
• Public URL: https://nottingham-repository.worktribe.com/output/3223776
• Publisher URL: https://gut.bmj.com/content/62/7/961