Mr JESUS MOLINAR DIAZ Jesus.MolinarDiaz3@nottingham.ac.uk
RESEARCH FELLOW
Ferromagnetic Cytocompatible Glass-Ceramic Porous Microspheres for Magnetic Hyperthermia Applications
Molinar‐Díaz, Jesús; Woodliffe, John Luke; Milborne, Benjamin; Murrell, Lauren; Islam, Md Towhidul; Steer, Elisabeth; Weston, Nicola; Morley, Nicola A.; Brown, Paul D.; Ahmed, Ifty
Authors
John Luke Woodliffe
Benjamin Milborne
Lauren Murrell
Md Towhidul Islam
Elisabeth Steer
Nicola Weston
Nicola A. Morley
Professor PAUL BROWN PAUL.BROWN@NOTTINGHAM.AC.UK
PROFESSOR OF MATERIALS CHARACTERISATION
Professor IFTY AHMED ifty.ahmed@nottingham.ac.uk
PROFESSOR OF MATERIALS SCIENCE AND ENGINEERING
Abstract
Highly porous, ferromagnetic glass-ceramic P40-Fe3O4 microspheres (125–212 µm) with enhanced cytocompatibility have been manufactured for the first time via a facile, rapid, single-stage flame spheroidization process. Dispersions of Fe3O4 and Ca2Fe2O5 domains (≈10 µm) embedded within P40 (40P2O5-16CaO-24MgO-20Na2O in mol%) phosphate-based glass matrices show evidence for remanent magnetization (0.2 Am2 kg−1) and provide for controlled induction heating to a constant level of 41.9 °C, making these materials highly appropriate for localized magnetic hyperthermia applications. Complementary, cytocompatibility investigations confirm the suitability of P40-Fe3O4 porous microspheres for biomedical applications. It is suggested that the flame-spheroidization process opens up new opportunities for the development of innovative synergistic biomaterials, toward bone-tissue regenerative applications.
Citation
Molinar‐Díaz, J., Woodliffe, J. L., Milborne, B., Murrell, L., Islam, M. T., Steer, E., Weston, N., Morley, N. A., Brown, P. D., & Ahmed, I. (2023). Ferromagnetic Cytocompatible Glass-Ceramic Porous Microspheres for Magnetic Hyperthermia Applications. Advanced Materials Interfaces, 10(11), Article 2202089. https://doi.org/10.1002/admi.202202089
| Journal Article Type | Article |
|---|---|
| Acceptance Date | Jan 17, 2023 |
| Online Publication Date | Mar 2, 2023 |
| Publication Date | Apr 14, 2023 |
| Deposit Date | Mar 5, 2023 |
| Publicly Available Date | Apr 4, 2023 |
| Journal | Advanced Materials Interfaces |
| Electronic ISSN | 2196-7350 |
| Publisher | Wiley |
| Peer Reviewed | Peer Reviewed |
| Volume | 10 |
| Issue | 11 |
| Article Number | 2202089 |
| DOI | https://doi.org/10.1002/admi.202202089 |
| Keywords | Bioactive glasses; magnetic hyperthermia; magnetic particles; porous microspheres |
| Public URL | https://nottingham-repository.worktribe.com/output/17947142 |
| Publisher URL | https://onlinelibrary.wiley.com/doi/10.1002/admi.202202089 |
Files
Adv Materials Inter - 2023 - Molinar ? D Az - Ferromagnetic Cytocompatible Glass ? Ceramic Porous Microspheres For Magnetic
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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