Rosa Sanchez Panchuelo
Somatotopy in the human somatosensory system
Sanchez Panchuelo, Rosa; Besle, Julien; Schluppeck, Denis; Humberstone, Miles; Francis, Susan
Authors
Julien Besle
Dr DENIS SCHLUPPECK DENIS.SCHLUPPECK@NOTTINGHAM.AC.UK
ASSOCIATE PROFESSOR
Miles Humberstone
Professor SUSAN FRANCIS susan.francis@nottingham.ac.uk
PROFESSOR OF PHYSICS
Abstract
Previous functional magnetic resonance imaging (fMRI) studies have demonstrated digit somatotopy in primary somatosensory cortex (SI), and even shown that at high spatial resolution it is possible to resolve within-digit somatotopy. However, fMRI studies have failed to resolve the spatial organisation of digit representations in secondary somatosensory cortex (SII). One of the major limitations of high spatial resolution fMRI studies of the somatosensory system has been the long acquisition time needed to acquire slices spanning both SI and SII. Here, we exploit the increased blood oxygenation level dependent contrast of ultra-high-field (7 Tesla) fMRI and the use of multiband imaging to study the topographic organisation in SI and SII with high spatial resolution at the individual subject level. A total of n = 6 subjects underwent vibrotactile stimulation of their face, hand digits and foot (body imaging) and their individual hand digits (digit mapping) for each left and right sides of the body. In addition, n = 2 subjects participated only in the body imaging experiment on both their left and right sides. We show an orderly representation of the face, hand digits and foot in contralateral primary cortex in each individual subject. In SII, there is clear separation of the body areas of the face, hand and foot but the spatial organisation varies across individual subjects. However, separate representation of the individual digits of the hand in SII could not be resolved, even at the spatial resolution of 1.5 mm due to largely overlapping representations.
Citation
Sanchez Panchuelo, R., Besle, J., Schluppeck, D., Humberstone, M., & Francis, S. (2018). Somatotopy in the human somatosensory system. Frontiers in Human Neuroscience, 12, Article 235. https://doi.org/10.3389/fnhum.2018.00235
Journal Article Type | Article |
---|---|
Acceptance Date | May 22, 2018 |
Online Publication Date | Jun 12, 2018 |
Publication Date | Jun 12, 2018 |
Deposit Date | Sep 4, 2018 |
Publicly Available Date | Sep 5, 2018 |
Electronic ISSN | 1662-5161 |
Publisher | Frontiers Media |
Peer Reviewed | Peer Reviewed |
Volume | 12 |
Article Number | 235 |
DOI | https://doi.org/10.3389/fnhum.2018.00235 |
Keywords | primary somatosensory cortex, secondary somatosensory cortex, somatotopy, digits, fMRI, ultra-high field |
Public URL | https://nottingham-repository.worktribe.com/output/1059808 |
Publisher URL | https://www.frontiersin.org/articles/10.3389/fnhum.2018.00235/full |
Contract Date | Sep 4, 2018 |
Files
Fnhum-12-00235
(7 Mb)
PDF
Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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