Outputs (2)

Modelling the distribution of the oxygen-haemoglobin dissociation curve in vivo: An observational study (2025)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., Cruickshank, S., Hammond-Pears, S., Shaw, D., Card, T. R., & Fogarty, A. W. (2025). Modelling the distribution of the oxygen-haemoglobin dissociation curve in vivo: An observational study. Respiratory Physiology and Neurobiology, 333, Article 104400. https://doi.org/10.1016/j.resp.2025.104400

Few studies have explored the variability of the oxygen-haemoglobin dissociation curve in vivo.

96,428 blood gas measurements were obtained (80,376 arterial, 6959 venous) from a cohort of 7656 patients who were admitted to a large UK teaching hosp... Read More about Modelling the distribution of the oxygen-haemoglobin dissociation curve in vivo: An observational study.

COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients (2025)
Journal Article
Crooks, C. J., West, J., Jones, J., Hamilton, W., Bailey, S. E., Abel, G., Banerjea, A., Rees, C. J., Tamm, A., Nicholson, B. D., Benton, S. C., Hunt, N., COLOFIT, R. G., & Humes, D. J. (2025). COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients. Alimentary Pharmacology and Therapeutics, 61(5), 852-864. https://doi.org/10.1111/apt.18459

Background: Colorectal cancer (CRC) is the third most common cancer in the United Kingdom and the second largest cause of cancer death. Aim: To develop and validate a model using available information at the time of faecal immunochemical testing (FIT... Read More about COLOFIT: Development and Internal-External Validation of Models Using Age, Sex, Faecal Immunochemical and Blood Tests to Optimise Diagnosis of Colorectal Cancer in Symptomatic Patients.