Outputs (2)

The role of mesenchymal cells in cholangiocarcinoma (2024)
Journal Article
Sueca-Comes, M., Rusu, E. C., Ashworth, J. C., Collier, P., Probert, C., Ritchie, A., Meakin, M., Mongan, N. P., Egbuniwe, I. U., Andersen, J. B., Bates, D. O., & Grabowska, A. M. (2024). The role of mesenchymal cells in cholangiocarcinoma. Disease Models and Mechanisms, 17(12), Article dmm050716. https://doi.org/10.1242/dmm.050716

The tumour microenvironment (TME) significantly influences tumour formation and progression through dynamic interactions. Cholangiocarcinoma (CCA), a highly desmoplastic tumour, lacks early diagnostic biomarkers and has limited effective treatments o... Read More about The role of mesenchymal cells in cholangiocarcinoma.

Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles (2024)
Journal Article
Brown, T. J., Rutland, C. S., Rutland, C. S., Choi, K. K., Tse, F., Pfeffers, M. J., Peffers, M. J., Mongan, N. P., Arkill, K. P., Ritchie, A., Clarke, P. A., Ratan, H., Allegrucci, C., Grabowska, A. M., & James, V. (2024). Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles. Frontiers in Cell and Developmental Biology, 12, Article 1354606. https://doi.org/10.3389/fcell.2024.1354606

Prostate cancer (PCa) is a leading male malignancy worldwide, often progressing to bone metastasis, with limited curative options. Extracellular vesicles (EVs) have emerged as key players in cancer communication and metastasis, promoting the formatio... Read More about Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles.