Outputs (93)

Assessing the impact of posture on diaphragm morphology and function using an open upright MRI system – a pilot study (2020)
Journal Article
Safavi, S., Arthofer, C., Cooper, A., Harkin, J. W., Prayle, A. P., Sovani, M. P., Bolton, C. E., Gowland, P. A., & Hall, I. P. (2020). Assessing the impact of posture on diaphragm morphology and function using an open upright MRI system – a pilot study. European Journal of Radiology, 130, Article 109196. https://doi.org/10.1016/j.ejrad.2020.109196

Purpose
The diaphragm is the most important muscle of respiration. Disorders of the diaphragm can have a deleterious impact on respiratory function. We aimed to evaluate the use of an open-configuration upright low-field MRI system to assess diaphra... Read More about Assessing the impact of posture on diaphragm morphology and function using an open upright MRI system – a pilot study.

A nociresponsive specific area of human somatosensory cortex within BA3a: BA3c? (2020)
Journal Article
Sanchez Panchuelo, R. M., Eldeghaidy, S., Marshall, A., McGlone, F., Francis, S. T., & Favorov, O. (2020). A nociresponsive specific area of human somatosensory cortex within BA3a: BA3c?. NeuroImage, 221, Article 117187. https://doi.org/10.1016/j.neuroimage.2020.117187

© 2020 It is well recognized that in primates, including humans, noxious body stimulation evokes a neural response in the posterior bank of the central sulcus, in Brodmann cytoarchitectonic subdivisions 3b and 1 of the primary somatosensory cortex. T... Read More about A nociresponsive specific area of human somatosensory cortex within BA3a: BA3c?.

Dynamic Colon Model (DCM): A Cine-MRI Informed Biorelevant In Vitro Model of the Human Proximal Large Intestine Characterized by Positron Imaging Techniques (2020)
Journal Article
Stamatopoulos, K., Karandikar, S., Goldstein, M., O’Farrell, C., Marciani, L., Sulaiman, S., Hoad, C. L., Simmons, M. J. H., & Batchelor, H. K. (2020). Dynamic Colon Model (DCM): A Cine-MRI Informed Biorelevant In Vitro Model of the Human Proximal Large Intestine Characterized by Positron Imaging Techniques. Pharmaceutics, 12(7), Article 659. https://doi.org/10.3390/pharmaceutics12070659

This work used in vivo MRI images of human colon wall motion to inform a biorelevant Dynamic Colon Model (DCM) to understand the interplay of wall motion, volume, viscosity, fluid, and particle motion within the colon lumen. Hydrodynamics and particl... Read More about Dynamic Colon Model (DCM): A Cine-MRI Informed Biorelevant In Vitro Model of the Human Proximal Large Intestine Characterized by Positron Imaging Techniques.

Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial (2020)
Journal Article
Gunn, D., Murthy, R., Major, G., Wilkinson-Smith, V., Hoad, C., Marciani, L., Remes-Troche, J., Gil, S., Rossi, M., Harris, H. C., Jarvis, J., Warren, F. J., Whelan, K., & Spiller, R. (2020). Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial. American Journal of Clinical Nutrition, 112(3), 595–602. https://doi.org/10.1093/ajcn/nqaa173

Background

Wheat bran, nopal, and psyllium are examples of particulate, viscous and particulate, and viscous fibers, respectively, with laxative properties yet contrasting fermentability.

Objectives

We assessed the fermentability of these fi... Read More about Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial.

Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial (2020)
Journal Article
Tanasescu, R., Tench, C. R., Constantinescu, C. S., Telford, G., Singh, S., Frakich, N., Onion, D., Auer, D. P., Gran, B., Evangelou, N., Falah, Y., Ranshaw, C., Cantacessi, C., Jenkins, T. P., & Pritchard, D. I. (2020). Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial. JAMA Neurology, 77(9), 1089-1098. https://doi.org/10.1001/jamaneurol.2020.1118

© 2020 American Medical Association. All rights reserved. Importance: Studies suggest gut worms induce immune responses that can protect against multiple sclerosis (MS). To our knowledge, there are no controlled treatment trials with helminth in MS.... Read More about Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial.

Development of Disordered Eating Behaviors and Comorbid Depressive Symptoms in Adolescence: Neural and Psychopathological Predictors (2020)
Journal Article
Zhang, Z., Robinson, L., Jia, T., Quinlan, E. B., Tay, N., Chu, C., Barker, E. D., Banaschewski, T., Barker, G. J., Bokde, A. L., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Stringaris, A., Penttilä, J., van Noort, B., …Desrivières, S. (2021). Development of Disordered Eating Behaviors and Comorbid Depressive Symptoms in Adolescence: Neural and Psychopathological Predictors. Biological Psychiatry, 90(12), 853-862. https://doi.org/10.1016/j.biopsych.2020.06.003

BACKGROUND:
Eating disorders are common in adolescence, devastating and strongly comorbid with other psychiatric disorders. Yet, little is known about their etiology to develop effective preventive measures.

METHODS:
Longitudinal assessments of... Read More about Development of Disordered Eating Behaviors and Comorbid Depressive Symptoms in Adolescence: Neural and Psychopathological Predictors.

Multi-channel whole-head OPM-MEG: Helmet design and a comparison with a conventional system (2020)
Journal Article
Hill, R. M., Boto, E., Rea, M., Holmes, N., Leggett, J., Coles, L. A., Papastavrou, M., Everton, S., Hunt, B. A., Sims, D., Osborne, J., Shah, V., Bowtell, R., & Brookes, M. J. (2020). Multi-channel whole-head OPM-MEG: Helmet design and a comparison with a conventional system. NeuroImage, 219, Article 116995. https://doi.org/10.1016/j.neuroimage.2020.116995

© 2020 The Authors Magnetoencephalography (MEG) is a powerful technique for functional neuroimaging, offering a non-invasive window on brain electrophysiology. MEG systems have traditionally been based on cryogenic sensors which detect the small extr... Read More about Multi-channel whole-head OPM-MEG: Helmet design and a comparison with a conventional system.

The haemodynamics of the human placenta in utero (2020)
Journal Article
Dellschaft, N. S., Hutchinson, G., Shah, S., Jones, N. W., Bradley, C., Leach, L., Platt, C., Bowtell, R., & Gowland, P. A. (2020). The haemodynamics of the human placenta in utero. PLoS Biology, 18(5), Article e3000676. https://doi.org/10.1371/journal.pbio.3000676

© 2020 Dellschaft et al. We have used magnetic resonance imaging (MRI) to provide important new insights into the function of the human placenta in utero. We have measured slow net flow and high net oxygenation in the placenta in vivo, which are cons... Read More about The haemodynamics of the human placenta in utero.

Crystal Structure Directed Catalysis by Aluminum Metal-Organic Framework: Mechanistic Insight into the Role of Coordination of Al Sites and Entrance Size of Catalytic Pocket (2020)
Journal Article
Maity, A., Singh, B., Sharma, K., Paul, S., Madhu, P. K., & Polshettiwar, V. (2020). Crystal Structure Directed Catalysis by Aluminum Metal-Organic Framework: Mechanistic Insight into the Role of Coordination of Al Sites and Entrance Size of Catalytic Pocket. ACS Materials Letters, 2(7), 699-704. https://doi.org/10.1021/acsmaterialslett.9b00527

© 2020 American Chemical Society. The use of metal-organic frameworks (MOFs) in the field of catalysis is growing exponentially due to their high surface area and distinctive active sites. In this work, we report a novel understanding of the active s... Read More about Crystal Structure Directed Catalysis by Aluminum Metal-Organic Framework: Mechanistic Insight into the Role of Coordination of Al Sites and Entrance Size of Catalytic Pocket.

Pandemic preparedness of community pharmacies for COVID-19 (2020)
Journal Article
Bahlol, M., & Dewey, R. S. (2021). Pandemic preparedness of community pharmacies for COVID-19. Research in Social and Administrative Pharmacy, 17(1), 1888-1896. https://doi.org/10.1016/j.sapharm.2020.05.009

© 2020 Elsevier Inc. Background: Community pharmacies provide an important healthcare service, which is broadly established, and constitutes the preferred and initial contact for members of the community. The significant value of community pharmacies... Read More about Pandemic preparedness of community pharmacies for COVID-19.