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Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume (2024)
Journal Article
Hu, J., Craig, M. S., Knight, S. P., De Looze, C., Meaney, J. F., Kenney, R. A., Chen, X., & Chappell, M. A. (2025). Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume. Magnetic Resonance in Medicine, 93(4), 1807-1820. https://doi.org/10.1002/mrm.30376

Purpose
One possible contributing factor for cerebral blood flow (CBF) decline in normal aging is the increase in partial volume effects due to brain atrophy, as cortical thinning can exacerbate the contamination of gray-matter (GM) voxels by other... Read More about Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume.

Boundary-wise loss for medical image segmentation based on fuzzy rough sets (2024)
Journal Article
Lin, Q., Chen, X., Chen, C., & Garibaldi, J. M. (2024). Boundary-wise loss for medical image segmentation based on fuzzy rough sets. Information Sciences, 661, Article 120183. https://doi.org/10.1016/j.ins.2024.120183

The loss function plays an important role in deep learning models as it determines the model convergence behavior and performance. In semantic segmentation, many methods utilize pixel-wise (e.g. cross-entropy) and region-wise (e.g. dice) losses while... Read More about Boundary-wise loss for medical image segmentation based on fuzzy rough sets.

Fuzzy Uncertainty-Based Out-of-Distribution Detection Algorithm for Semantic Segmentation (2023)
Presentation / Conference Contribution
Lin, Q., Chen, X., Chen, C., Pekaslan, D., & Garibaldi, J. M. (2023, August). Fuzzy Uncertainty-Based Out-of-Distribution Detection Algorithm for Semantic Segmentation. Presented at 2023 IEEE International Conference on Fuzzy Systems (FUZZ), Songdo Incheon, Korea

Deep learning models have achieved high performance in numerous semantic segmentation tasks. However, when the input data at test time do not resemble the training data, deep learning models can not handle them properly and will probably produce poor... Read More about Fuzzy Uncertainty-Based Out-of-Distribution Detection Algorithm for Semantic Segmentation.

A Novel Quality Control Algorithm for Medical Image Segmentation Based on Fuzzy Uncertainty (2022)
Journal Article
Lin, Q., Chen, X., Chen, C., & Garibaldi, J. M. (2022). A Novel Quality Control Algorithm for Medical Image Segmentation Based on Fuzzy Uncertainty. IEEE Transactions on Fuzzy Systems, 31(8), 2532-2544. https://doi.org/10.1109/tfuzz.2022.3228332

Deep learning methods have achieved an excellent performance in medical image segmentation. However, the practical application of deep learning-based segmentation models is limited in clinical settings due to the lack of reliable information about th... Read More about A Novel Quality Control Algorithm for Medical Image Segmentation Based on Fuzzy Uncertainty.

Quality Quantification in Deep Convolutional Neural Networks for Skin Lesion Segmentation using Fuzzy Uncertainty Measurement (2022)
Presentation / Conference Contribution
Lin, Q., Chen, X., Chen, C., & Garibaldi, J. M. (2022, July). Quality Quantification in Deep Convolutional Neural Networks for Skin Lesion Segmentation using Fuzzy Uncertainty Measurement. Presented at 2022 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE), Padua, Italy

Deep convolutional neural networks (DCNN)-based methods have achieved promising performance in semantic image segmentation. However, in practical applications, it is important not only to produce the segmentation result but also to inform the segment... Read More about Quality Quantification in Deep Convolutional Neural Networks for Skin Lesion Segmentation using Fuzzy Uncertainty Measurement.

LMISA: A Lightweight Multi-modality Image Segmentation Network via Domain Adaptation using Gradient Magnitude and Shape Constraint (2022)
Journal Article
Jafari, M., Francis, S., Garibaldi, J. M., & Chen, X. (2022). LMISA: A Lightweight Multi-modality Image Segmentation Network via Domain Adaptation using Gradient Magnitude and Shape Constraint. Medical Image Analysis, 81, Article 102536. https://doi.org/10.1016/j.media.2022.102536

In medical image segmentation, supervised machine learning models trained using one image modality (e.g. computed tomography (CT)) are often prone to failure when applied to another image modality (e.g. magnetic resonance imaging (MRI)) even for the... Read More about LMISA: A Lightweight Multi-modality Image Segmentation Network via Domain Adaptation using Gradient Magnitude and Shape Constraint.

Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review (2021)
Journal Article
Jathanna, N., Podlasek, A., Sokol, A., Auer, D., Chen, X., & Jamil-Copley, S. (2021). Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review. Cardiovascular Digital Health Journal, 2(6), S21-S29. https://doi.org/10.1016/j.cvdhj.2021.11.005

Background: Accurate, rapid quantification of ventricular scar using cardiac magnetic resonance imaging (CMR) carries importance in arrhythmia management and patient prognosis. Artificial intelligence (AI) has been applied to other radiological chall... Read More about Diagnostic utility of artificial intelligence for left ventricular scar identification using cardiac magnetic resonance imaging—A systematic review.

FuzzyDCNN: Incorporating Fuzzy Integral Layers to Deep Convolutional Neural Networks for Image Segmentation (2021)
Presentation / Conference Contribution
Lin, Q., Chen, X., Chen, C., & Garibaldi, J. M. (2021, July). FuzzyDCNN: Incorporating Fuzzy Integral Layers to Deep Convolutional Neural Networks for Image Segmentation. Presented at IEEE International Conference on Fuzzy Systems (FUZZ-IEEE 2021), Luxembourg, Luxembourg

Convolutional neural networks (CNNs) have achieved the state-of-the-art performance in many application areas, due to the capability of automatically extracting and aggregating spatial and channel-wise features from images. Most recent studies have c... Read More about FuzzyDCNN: Incorporating Fuzzy Integral Layers to Deep Convolutional Neural Networks for Image Segmentation.

Deep Learning with Dynamically Weighted Loss Function for Sensor-Based Prognostics and Health Management (2020)
Journal Article
Rengasamy, D., Jafari, M., Rothwell, B., Chen, X., & Figueredo, G. P. (2021). Deep Learning with Dynamically Weighted Loss Function for Sensor-Based Prognostics and Health Management. Sensors, 20(3), Article 723. https://doi.org/10.3390/s20030723

Deep learning has been employed to prognostic and health management of automotive and aerospace with promising results. Literature in this area has revealed that most contributions regarding deep learning is largely focused on the model’s architectur... Read More about Deep Learning with Dynamically Weighted Loss Function for Sensor-Based Prognostics and Health Management.

Dual Adaptive Pyramid Network for Cross-Stain Histopathology Image Segmentation (2019)
Book Chapter
Hou, X., Liu, J., Xu, B., Liu, B., Chen, X., Garibaldi, J., Ilyas, M., Ellis, I., & Qiu, G. (2019). Dual Adaptive Pyramid Network for Cross-Stain Histopathology Image Segmentation. In Medical Image Computing and Computer Assisted Intervention – MICCAI 2019: 22nd International Conference, Shenzhen, China, October 13–17, 2019, Proceedings, Part II (101-109). Springer Verlag. https://doi.org/10.1007/978-3-030-32245-8_12

Supervised semantic segmentation normally assumes the test data being in a similar data domain as the training data. However, in practice, the domain mismatch between the training and unseen data could lead to a significant performance drop. Obtainin... Read More about Dual Adaptive Pyramid Network for Cross-Stain Histopathology Image Segmentation.