Outputs (1547)

The biomolecules of Euglena gracilis: Harnessing biology for natural solutions to future problems (2024)
Journal Article
Bedard, S., Roxborough, E., O'Neill, E., & Mangal, V. (2024). The biomolecules of Euglena gracilis: Harnessing biology for natural solutions to future problems. Protist, 175(4), Article 126044. https://doi.org/10.1016/j.protis.2024.126044

Over the past decade, the autotrophic and heterotrophic protist Euglena gracilis (E. gracilis) has gained popularity across the studies of environmental science, biosynthesis experiments, and nutritional substitutes. The unique physiology and versati... Read More about The biomolecules of Euglena gracilis: Harnessing biology for natural solutions to future problems.

Solvent flashcards: a visualisation tool for sustainable chemistry. (2024)
Journal Article
Heeley, J., Boobier, S., & Hirst, J. D. (2024). Solvent flashcards: a visualisation tool for sustainable chemistry. Journal of Cheminformatics, 16(1), Article 60. https://doi.org/10.1186/s13321-024-00854-9

Selecting greener solvents during experiment design is imperative for greener chemistry. While many solvent selection guides are currently used in the pharmaceutical industry, these are often paper-based guides which can make it difficult to identify... Read More about Solvent flashcards: a visualisation tool for sustainable chemistry..

Spectroscopy Unlocked: An Escape Room activity for Introductory Chemistry Courses (2024)
Journal Article
Mahomed, M., Sisodia, L., Williams, D. P., & Villa-Marcos, B. (2024). Spectroscopy Unlocked: An Escape Room activity for Introductory Chemistry Courses. Journal of Chemical Education, 101(6), 2570–2575. https://doi.org/10.1021/acs.jchemed.3c01320

Spectroscopy Unlocked is an escape room activity cocreated by student and staff authors. The escape room presents students with a series of activities that they must complete in the laboratory in order to reveal a series of codes and clues that can b... Read More about Spectroscopy Unlocked: An Escape Room activity for Introductory Chemistry Courses.

Porous isoreticular non-metal organic frameworks (2024)
Journal Article
O’Shaughnessy, M., Glover, J., Hafizi, R., Barhi, M., Clowes, R., Chong, S. Y., Argent, S. P., Day, G. M., & Cooper, A. I. (2024). Porous isoreticular non-metal organic frameworks. Nature, 630(8015), 102-108. https://doi.org/10.1038/s41586-024-07353-9

Metal–organic frameworks (MOFs) are useful synthetic materials that are built by the programmed assembly of metal nodes and organic linkers1. The success of MOFs results from the isoreticular principle2, which allows families of structurally analogou... Read More about Porous isoreticular non-metal organic frameworks.

Nickel‐Catalysed syn‐Selective Arylnickelation and Cyclisation of Ketone/Imine‐Tethered Terminal Alkynes with Arylboronic Acids (2024)
Journal Article
Morgan, D. M., Lam, H. W., & Guiry, P. J. (2024). Nickel‐Catalysed syn‐Selective Arylnickelation and Cyclisation of Ketone/Imine‐Tethered Terminal Alkynes with Arylboronic Acids. European Journal of Organic Chemistry, 27(23), Article e202400445. https://doi.org/10.1002/ejoc.202400445

Herein we report a syn-arylnickelative cyclisation with ketone- and imine-tethered terminal alkynes (16 examples) in yields of up to 89 %. The reaction proceeds via a syn-aryl nickelation of a terminal alkyne followed by cyclisation of the resulting... Read More about Nickel‐Catalysed syn‐Selective Arylnickelation and Cyclisation of Ketone/Imine‐Tethered Terminal Alkynes with Arylboronic Acids.

Zero-valent iron (ZVI) facilitated in-situ selenium (Se) immobilization and its recovery by magnetic separation: Mechanisms and implications for microbial ecology (2024)
Journal Article
Wang, Z., Lü, C., Wang, Y., Gomes, R. L., Clarke, C. J., & Gomes, H. I. (2024). Zero-valent iron (ZVI) facilitated in-situ selenium (Se) immobilization and its recovery by magnetic separation: Mechanisms and implications for microbial ecology. Journal of Hazardous Materials, 473, Article 134591. https://doi.org/10.1016/j.jhazmat.2024.134591

Selenium (Se(VI)) is environmentally toxic. One of the most popular reducing agents for Se(VI) remediation is zero-valent iron (ZVI). However, most ZVI studies were carried out in water matrices, and the recovery of reduced Se has not been investigat... Read More about Zero-valent iron (ZVI) facilitated in-situ selenium (Se) immobilization and its recovery by magnetic separation: Mechanisms and implications for microbial ecology.

Magnetic structure and properties of the honeycomb antiferromagnet [Na(OH2)3]Mn(NCS)3 (2024)
Journal Article
Geers, M., Gill, T. B., Burnett, A. D., Bassey, E. N., Fabelo, O., Cañadillas-Delgado, L., & Cliffe, M. J. (2024). Magnetic structure and properties of the honeycomb antiferromagnet [Na(OH2)3]Mn(NCS)3. Physical Chemistry Chemical Physics, 26(22), 15844-15849. https://doi.org/10.1039/d4cp01265h

We report the magnetic structure and properties of a thiocyanate-based honeycomb magnet [Na(OH2)3]Mn(NCS)3 which crystallises in the unusual low-symmetry trigonal space group P3̄. Magnetic measurements on powder samples show this material is an antif... Read More about Magnetic structure and properties of the honeycomb antiferromagnet [Na(OH2)3]Mn(NCS)3.

Peptide macrocyclisation via intramolecular interception of visible-light-mediated desulfurisation (2024)
Journal Article
Smith, F. R., Meehan, D., Griffiths, R. C., Knowles, H. J., Zhang, P., Williams, H. E., Wilson, A. J., & Mitchell, N. J. (2024). Peptide macrocyclisation via intramolecular interception of visible-light-mediated desulfurisation. Chemical Science, 15(25), 9612-9619. https://doi.org/10.1039/d3sc05865d

Synthetic methods that enable the macrocyclisation of peptides facilitate the development of effective therapeutic and diagnostic tools. Herein we report a peptide cyclisation strategy based on intramolecular interception of visible-light-mediated cy... Read More about Peptide macrocyclisation via intramolecular interception of visible-light-mediated desulfurisation.

Enabling high-fidelity personalised pharmaceutical tablets through multimaterial inkjet 3D printing with a water-soluble excipient (2024)
Journal Article
Rivers, G., Lion, A., Putri, N. R. E., Rance, G. A., Moloney, C., Taresco, V., Crucitti, V. C., Constantin, H., Evangelista Barreiros, M. I., Cantu, L. R., Tuck, C. J., Rose, F. R., Hague, R. J., Roberts, C. J., Turyanska, L., Wildman, R. D., & He, Y. (2024). Enabling high-fidelity personalised pharmaceutical tablets through multimaterial inkjet 3D printing with a water-soluble excipient. Materials Today Advances, 22, Article 100493. https://doi.org/10.1016/j.mtadv.2024.100493

Additive manufacturing offers manufacture of personalised pharmaceutical tablets through design freedoms and material deposition control at an individual voxel level. This control goes beyond geometry and materials choices: inkjet based 3D printing e... Read More about Enabling high-fidelity personalised pharmaceutical tablets through multimaterial inkjet 3D printing with a water-soluble excipient.

Enantioselective de novo synthesis of 14-hydroxy-6-oxomorphinans (2024)
Journal Article
Moore, J. C., Modell, L., Glenn, J. R., Jones, K. D., Argent, S. P., Lane, J. R., Canals, M., & Lam, H. W. (2024). Enantioselective de novo synthesis of 14-hydroxy-6-oxomorphinans. Chemical Communications, 60(47), 6007-6010. https://doi.org/10.1039/d4cc01788a

The enantioselective de novo synthesis of pharmacologically important 14-hydroxy-6-oxomorphinans is described. 4,5-Desoxynaltrexone and 4,5-desoxynaloxone were prepared using this route and their biological activities against the opioid receptors wer... Read More about Enantioselective de novo synthesis of 14-hydroxy-6-oxomorphinans.