Outputs (67)

Fat emulsion intragastric stability and droplet size modulate gastrointestinal responses and subsequent food intake in young adults (2015)
Journal Article
Hussein, M., Hoad, C., Wright, J., Singh, G., Stephenson, M., Cox, E., Placidi, E., Pritchard, S., Costigan, C., Ribeiro, H., Ciampi, E., Nandi, A., Hedges, N., Sanderson, P., Peters, H., Rayment, P., Spiller, R., Gowland, P., & Marciani, L. (2015). Fat emulsion intragastric stability and droplet size modulate gastrointestinal responses and subsequent food intake in young adults. Journal of Nutrition, 145(6), 1170-1177. https://doi.org/10.3945/jn.114.204339

Background: Intragastric creaming and droplet size of fat emulsions may affect intragastric behavior and gastrointestinal and satiety responses.

Objectives: We tested the hypotheses that gastrointestinal physiologic responses and satiety will be i... Read More about Fat emulsion intragastric stability and droplet size modulate gastrointestinal responses and subsequent food intake in young adults.

A mechanistic multi-centre, parallel group, randomised placebo controlled trial of Mesalazine for treatment of irritable bowel syndrome with diarrhoea (IBS-D) (2015)
Journal Article
Lam, C., Tan, W., Leighton, M., Hastings, M., Lingaya, M., Falcone, Y., Zhou, X., Xu, L., Whorwell, P., Walls, A., Zaitoun, A. M., Montgomery, A., & Spiller, R. C. (2015). A mechanistic multi-centre, parallel group, randomised placebo controlled trial of Mesalazine for treatment of irritable bowel syndrome with diarrhoea (IBS-D). Gut, 65(1), https://doi.org/10.1136/gutjnl-2015-309122

Introduction: Immune activation has been reported in the mucosa of irritable bowel syndrome patients with diarrhoea (IBS-D) and some small studies have suggested that Mesalazine may reduce symptoms. We performed a double blind, randomised placebo con... Read More about A mechanistic multi-centre, parallel group, randomised placebo controlled trial of Mesalazine for treatment of irritable bowel syndrome with diarrhoea (IBS-D).

Aerated drinks increase gastric volume and reduce appetite as assessed by MRI: a randomized, balanced, crossover trial (2015)
Journal Article
Murray, K., Placidi, E., Schuring, E. A. H., Hoad, C. L., Koppenol, W., Arnaudov, L. N., Blom, W. A. M., Pritchard, S. E., Stoyanov, S. D., Gowland, P. A., Spiller, R. C., Peters, H. P. F., & Marciani, L. (2015). Aerated drinks increase gastric volume and reduce appetite as assessed by MRI: a randomized, balanced, crossover trial. American Journal of Clinical Nutrition, 101(2), 270-278. https://doi.org/10.3945/ajcn.114.096974

Magnetic resonance spectroscopy measurements of intragastric fat fraction of oil emulsions in humans (2014)
Journal Article
Hussein, M. O., Hoad, C. L., Stephenson, M. C., Cox, E. F., Placidi, E., Pritchard, S. E., Costigan, C., Ribeiro, H., Ciampi, E., Rayment, P., Nandi, A., Hedges, N., Sanderson, P., Peters, H. P., Kruse, I., Marciani, L., Spiller, R. C., & Gowland, P. A. (2015). Magnetic resonance spectroscopy measurements of intragastric fat fraction of oil emulsions in humans. European Journal of Lipid Science and Technology, 117(1), 31-36. https://doi.org/10.1002/ejlt.201400058

A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea (2013)
Journal Article
Garsed, K., Chernova, J., Hastings, M., Lam, C., Marciani, L., Singh, G., Henry, A. P., Hall, I. P., Whorwell, P., & Spiller, R. C. (2014). A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea. Gut, 63(10), 1617-1625. https://doi.org/10.1136/gutjnl-2013-305989

Background: Irritable bowel syndrome with diarrhoea (IBS-D) is particularly debilitating due to urgency and episodic incontinence. Some 5-hydroxytryptamine 3 (5-HT3) receptor antagonists (5-HT3RAs) have proven effective but have serious side effects.... Read More about A randomised trial of ondansetron for the treatment of irritable bowel syndrome with diarrhoea.

Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit (2013)
Journal Article
Tooth, D., Garsed, K., Singh, G., Marciani, L., Lam, C., Fordham, I., Fields, A., Banwait, R., Lingaya, M., Layfield, R., Hastings, M., Whorwell, P., & Spiller, R. C. (2014). Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit. Gut, 63(5), 753-760. https://doi.org/10.1136/gutjnl-2012-304042

Effects of various food ingredients on gall bladder emptying (2013)
Journal Article
Marciani, L., Cox, E., Hoad, C., Totman, J. J., Costigan, C., Singh, G., Shepherd, V., Chalkley, L., Robinson, M., Ison, R., Gowland, P. A., & Spiller, R. C. (2013). Effects of various food ingredients on gall bladder emptying. European Journal of Clinical Nutrition, 67(11), https://doi.org/10.1038/ejcn.2013.168

Background/objectives: The emptying of the gall bladder in response to feeding is pivotal for the digestion of fat, but the role of various food ingredients in contracting the gall bladder postprandially is not well understood. We hypothesized that d... Read More about Effects of various food ingredients on gall bladder emptying.